Steroidogenesis Inhibitors International Company Profile

19:21 EST 23rd November 2017 | BioPortfolio

Drug Discovery


2001 East Flamingo Boulevard Suite 100B
Las Vegas
United States of America


Phone: 702 735 7001
Fax: 702 737 7016

News Articles [478 Associated News Articles listed on BioPortfolio]

HAT Inhibitors: Interpret With Care

There are quite a few histone deacetylase inhibitors out there, from research tools to FDA-approved drugs. Those inhibit the enzymes that remove the acetyl epigenetic markers from histone proteins ...

Novel therapy decreases incidence of bleeding by 87% in hemophilia A patients with inhibitors

An international team of hematologists including Guy Young, MD, of Children's Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a novel therapy called emicizumab, dec...

HIV Drug Market by Medication class multiclass combination drugs, nucleoside reverse transcriptase inhibitors NRTIs, nonnucleoside reverse transcriptase inhibitors NNRTIs, protease inhibitors PIs, fusion inhibitors FI, entry inhibitors, and HIV integrase

Human Immunodeficiency Virus Hiv Attacks The Bodys Immune System, Making The Host System Susceptible To Infection, And Thus Leading To Complete Damage. The Virus Attacks The Cd4 Cells, Which Help The ...

Prolonged use of cancer inhibitors can lead to severe cardiovascular problems

Plk1 inhibitors have recently been acknowledged as an "Innovative Therapy for leukaemia" by the US Food and Drug Administration.

New Drug Classes for Diabetes Mean New Options

Dr Cyrus Desouza reviews GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT2 inhibitors, offering advice on which patients may benefit from each class. Endocrine Society

NewLink inks deal with AstraZeneca to test Imfinzi combo

IDO inhibitors like NewLink's indoximod are seen as a potentially fruitful pairing for PD-L1 inhibitors.   

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia

ACE-inhibitors and statins do not impact albuminuria in adolescents with type 1 diabetes mellitus: The AdDIT trial

1. In adolescents with type 1 diabetes mellitus, the albumin-to-creatinine ratio was not significantly changed by angiotensin-converting-enzyme (ACE) inhibitors alone, statins alone, or the two in com...

Drugs and Medications [437 Associated Drugs and Medications listed on BioPortfolio]

Pvp iodine prep pad [Professional Disposables International, Inc.]

Drug Facts

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PubMed Articles [1947 Associated PubMed Articles listed on BioPortfolio]

Neglected issues concerning teaching human adrenal steroidogenesis in popular biochemistry textbooks.

In the human body, the adrenal steroids collectively regulate a plethora of fundamental functions, including electrolyte and water balance, blood pressure, stress response, intermediary metabolism, in...

Steroidogenic disruptive effects of the serotonin-noradrenaline reuptake inhibitors duloxetine, venlafaxine and tramadol in the H295R cell assay and in a recombinant CYP17 assay.

The aim of this study was to determine the steroidogenic endocrine disrupting effect of the three most widely used serotonin-noradrenaline reuptake inhibitors duloxetine, venlafaxine and tramadol, usi...

NF-κB-vimentin is involved in steroidogenesis stimulated by mono-butyl phthalate in primary cultured ovarian granulosa cells.

Di-n-butyl phthalate (DBP) and its active metabolite, monobutyl phthalate (MBP) are the most common endocrine disrupting chemicals. Many studies indicated the effects of MBP on male steroidogenesis, h...

SAVE-AMD: Safety of VEGF Inhibitors in Age-Related Macular Degeneration.

To determine whether intraocular treatment with vascular endothelial growth factor (VEGF) inhibitors change systemic endothelial function (EF) in patients with neovascular age-related macular degenera...

International multi-centre study of pregnancy outcomes with interleukin-1 inhibitors.

To provide outcome data concerning pregnancies exposed to the Interleukin-1 (IL-1) inhibitors prior to conception in both men and women, during pregnancy and breast feeding.

Clinical Trials [1793 Associated Clinical Trials listed on BioPortfolio]

Human Chorionic Gonadotropin Stimulation Effects on Steroidogenesis in Men With Klinefelter Syndrome

The study design included six visits. During the first visit (visit 0), the subjects underwent physical examination(height, weight, body mass index (BMI), arm span, and upper segment measu...

The Malmö International Brother Study (MIBS)

Existing data support the concept that a genetic predisposition for inhibitor development exists. The aim of the Malmö International Brother Study (MIBS) is to evaluate genetic factors a...

Genetic Susceptibility to Factor VIII Inhibitors

This international study will identify genetic factors that may influence the development of inhibitory antibodies in patients with hemophilia A after treatment with factor VIII. Bleeding ...

Effects of Achieving Very Low LDL-Cholesterol After Treatment With Statins on Steroidogenesis and Cognition

We aimed to compare the effect of achieving an LDL-cholesterol

Effect of Aromatase Inhibitors on Bones and Genes

The primary objective of this 2-year pilot project is to test the hypothesis that skeletal response to aromatase inhibitors is determined by polymorphisms of the CYP19 gene.

Companies [1386 Associated Companies listed on BioPortfolio]

Steroidogenesis Inhibitors International

Drug Discovery

Amura Holdings Ltd

Amura has two complementary technology platforms which enable rapid and innovative drug discovery. AMcore™, the bicyclic core molecular scaffold chemistry and the computational screening and design...

Step Pharma

Step Pharma is focused on the development of a novel class of oral nucleotide synthesis inhibitors targeting CTPS1 for the improved treatment of a range of autoimmune diseases. Th...

Viamet Pharmaceuticals, Inc.

Viamet discovers and develops novel inhibitors of key metalloenzymes via an innovative and proprietary metal-binding approach, the Metallophile™ Technology. Viamet’s dis...

Amura Therapeutics Ltd

Amura has two complementary technology platforms which enable rapid and innovative drug discovery. AMcore™, the bicyclic core molecular scaffold chemistry and the computational screening and design...

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