Steroidogenesis Inhibitors International Company Profile

11:07 EDT 25th September 2018 | BioPortfolio

Drug Discovery


2001 East Flamingo Boulevard Suite 100B
Las Vegas
United States of America


Phone: 702 735 7001
Fax: 702 737 7016

News Articles [771 Associated News Articles listed on BioPortfolio]

DNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells

Hepatotoxicity of Immune Checkpoint Inhibitors

Immune checkpoint inhibitors have proven utility as a new class of anticancer drugs, but carry with them the risk of hepatotoxic and other immune-related adverse events. Liver International

SGLT-2 Inhibitors and GLP-1 Agonists Confer a Survival Benefit in Patients with Type 2 Diabetes

Sodium–glucose cotransporter-2 inhibitors and glucagon-like peptide-1 agonists conferred benefit, but dipeptidyl peptidase 4 inhibitors didn't have this effect.

Aclaris Therapeutics to Support Symposium on JAK Inhibitors at the International Investigative Dermatology 2018 Meeting

WAYNE, Pa., May 15, 2018 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ:ACRS), a dermatologist-led biopharmaceutical company committed to identifying, developing, and commercializing innova...

Development and clinical indications of PARP inhibitors

Dr O’Connor speaks with ecancer about the development and application of PARP inhibitors. He describes his research in treatment tolerability and the overlap of efficacy with observed PARP trapping...

Interleukin-6 (IL-6) Inhibitors Therapeutics Global Pipeline Analysis Report 2017 - Clinical ...

The study analyzed that the IL-6 inhibitors therapeutics pipeline comprises approximately 18 active drug candidates in different stages of development. Interleukin-6 inhibitors acts on the Read mo...

Tumor Necrosis Factor Inhibitors Drug Market, 2024 - Humira and Remicade Have Made it to the ...

Global Tumor Necrosis Factor Inhibitors Drug Market Dosage Price & Clinical Pipeline Outlook 2024 Report Highlights: Global TNF Inhibitors Market Trends Key TNF Inhibitors Drug Read mo...

Are PD-1 and PD-L1 Checkpoint Inhibitors As Good As We Thought?

Checkpoint inhibitors, especially those targeting PD-1 and PD-L1, are exploding in popularity. But how much of it is hype? The pipelines of biotech and pharma are filling up with combination therapie...

Drugs and Medications [437 Associated Drugs and Medications listed on BioPortfolio]

Pvp iodine prep pad [Professional Disposables International, Inc.]

Drug Facts

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PubMed Articles [1786 Associated PubMed Articles listed on BioPortfolio]

Monogenic Disorders of Adrenal Steroidogenesis.

Disorders of adrenal steroidogenesis comprise autosomal recessive conditions affecting steroidogenic enzymes of the adrenal cortex. Those are located within the 3 major branches of the steroidogenic m...

Functional screening of selective mitochondrial inhibitors of Plasmodium.

Phenotypic screening has produced most of the new chemical entities currently in clinical development for malaria, plus many lead compounds active against Plasmodium falciparum asexual stages. However...

A review of bullous pemphigoid associated with PD-1 and PD-L1 inhibitors.

Dermatologic toxicity represents a substantial portion of all immune-related adverse events (irAEs) associated with PD-1/PD-L1 inhibitors. Bullous pemphigoid (BP) is a rare cutaneous side effect of th...

The Role of Proteasome Inhibitor MG132 in 2,4-Dinitrofluorobenzene-Induced Atopic Dermatitis in NC/Nga Mice.

Although immunosuppressants for therapy of atopic dermatitis (AD) are still being sought, proteasome inhibitors are also potential candidates for the treatment of AD. Proteasome inhibitors exert vario...

Evaluation of chitosan and carboxymethyl cellulose as ecofriendly corrosion inhibitors for steel.

The study was aimed at establishing the possibility of using eco-friendly natural polymers to formulate corrosion inhibitors for sweet oil field environment. Against this background, the performance o...

Clinical Trials [2144 Associated Clinical Trials listed on BioPortfolio]

Human Chorionic Gonadotropin Stimulation Effects on Steroidogenesis in Men With Klinefelter Syndrome

The study design included six visits. During the first visit (visit 0), the subjects underwent physical examination(height, weight, body mass index (BMI), arm span, and upper segment measu...

Impact of Renin-Angiotensin System Inhibitors Continuation on Outcome After Major Surgery

More than 200 million major surgical procedures are performed annually worldwide. Many of these patients have comorbidities including hypertension and/or heart failure. Chronic treatment o...

The Malmö International Brother Study (MIBS)

Existing data support the concept that a genetic predisposition for inhibitor development exists. The aim of the Malmö International Brother Study (MIBS) is to evaluate genetic factors a...

Genetic Susceptibility to Factor VIII Inhibitors

This international study will identify genetic factors that may influence the development of inhibitory antibodies in patients with hemophilia A after treatment with factor VIII. Bleeding ...

Effects of Achieving Very Low LDL-Cholesterol After Treatment With Statins on Steroidogenesis and Cognition

We aimed to compare the effect of achieving an LDL-cholesterol

Companies [1436 Associated Companies listed on BioPortfolio]

Steroidogenesis Inhibitors International

Drug Discovery

Amura Holdings Ltd

Amura has two complementary technology platforms which enable rapid and innovative drug discovery. AMcore™, the bicyclic core molecular scaffold chemistry and the computational screening and design...

Step Pharma

Step Pharma is focused on the development of a novel class of oral nucleotide synthesis inhibitors targeting CTPS1 for the improved treatment of a range of autoimmune diseases. Th...

Viamet Pharmaceuticals, Inc.

Viamet discovers and develops novel inhibitors of key metalloenzymes via an innovative and proprietary metal-binding approach, the Metallophile™ Technology. Viamet’s dis...

Amura Therapeutics Ltd

Amura has two complementary technology platforms which enable rapid and innovative drug discovery. AMcore™, the bicyclic core molecular scaffold chemistry and the computational screening and design...

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Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...

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