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In the 1980s, Tanox scientists discovered a novel approach for the treatment of allergic disease by reducing the levels of immunoglobulin E (IgE) in the blood. IgE is one of a class of antibodies that is responsible for causing allergic reactions. In June 2003, an anti-IgE therapy, Xolair® (Omalizumab) For Subcutaneous Use, received approval from the U.S. Food and Drug Administration for the treatment of adults and adolescents (12 years of age and above) with moderate-to-severe persistent asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and whose symptoms are inadequately controlled with inhaled corticosteroids. In October of 2005, Xolair was approved for marketing in all 25 European Union states and is the first monoclonal antibody approved for the treatment of asthma in Europe. Tanox is committed to becoming a world leader in providing effective therapies for immune-mediated diseases, infectious disease, inflammation and cancer. Through the development and use of innovative technologies, we create products that address unmet medical needs by treating the underlying cause of disease.
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In the 1980s, Tanox scientists discovered a novel approach for the treatment of allergic disease by reducing the levels of immunoglobulin E (IgE) in the blood. IgE is one of a class of antibodies that...
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An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens. Examples of antigens include microorganisms (such as bacteria, fungi, parasites, and viruses) and chemicals. Antibodies may be produc...
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...