A-Viral ASA Company Profile

19:36 EST 13th December 2018 | BioPortfolio

The company was formally registered in 1986, but there were little activity until 1997. Then the company acquired its first patent application. The company had its first major public offering in the fall of 1998, at the same time when Einar Stokke became CEO. Since then more than 7 million Euros has been used for research, by far the major part of it on AV 1101.Numerous laboratory tests took place at the National Institute of Public Health in Oslo from 1998. Later laboratory testing has shifted towards our research partner, CLB-Sanquin in Amsterdam , which has been the centre for our lab. research for several years now.
Through studies of OxyPhenylButazone (OBP) AV 1101 was discovered. AV 1101 is 4-Hydroxy-OxyPhenylButazone. The chemical itself is known through literature only as a metabolite from PhenylButazone (PB), and A-Viral has a patent application for AV 1101 and many closely related forms for all therapeutic use in humans and animals. AV 1101 has recently acquired a patent grant in USA for use against inflammatory and autoimmune diseases.
(read more: Patents)
In 2001 A-Viral started to have its lab research done at CLB – Sanquin. A research group under professor Lucien Aarden (specialist in cellular immunology) started the work to find the basic functions of AV 1101. They perform a lot of testing with AV 1101, and measures how various blood cells react to AV 1101 under different conditions, measuring cell activation, proliferation and cytokine production. In the beginning they also tested on how HIV would propagate in the presence of AV 1101. They have also checked out metabolites of and conjugates from AV 1101, and tested which are still active. Assays for measuring AV 1101 in blood have been developed. New related substances are synthesized and tested, etc. This research is the basis for our understanding of AV 1101, and it is the platform on which we build our clinical research. And our team at CLB does additional analysis with blood samples from our clinical studies, retrieving important information about the function of AV 1101


Postboks 1780


Phone: 47 23118953
Fax: 47 23118959

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