Aegera Therapeutics Inc Company Profile

19:12 EDT 18th March 2018 | BioPortfolio

Aegera Therapeutics Inc. (“Aegera”) is a clinical stage biotechnology company focused on developing drugs that control apoptosis to address major unmet medical needs. Our two lead clinical programs are in development to induce apoptosis to kill cancer cells and to prevent apoptosis to save injured neuronal cells. AEG35156 targets the anti-apoptotic protein XIAP, and is currently in multiple human clinical trials for the treatment of solid tumors and leukemia; this same drug candidate may also have significant potential for the treatment of autoimmune diseases. Aegera’s second drug product, AEG33783, is a neuroprotective agent in Phase I clinical trials for the treatment of neuropathies induced by chemotherapy or diabetes. Building on our knowledge of apoptosis, neuronal signaling and the IAP protein family (Inhibitor of Apoptosis Proteins), Aegera is also working on the development of small molecule IAP inhibitors for the treatment of multiple cancers, inflammatory and autoimmune diseases.


810 chemin du Golf île des Soeurs (Montreal),
H3E 1A8


Phone: 514.288.5532
Fax: 514.288.9280

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PubMed Articles [404 Associated PubMed Articles listed on BioPortfolio]

Recent developments in intracellular protein delivery.

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Alternative therapeutics for self-limiting infections-An indirect approach to the antibiotic resistance challenge.

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Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

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