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Alnylam Pharmaceuticals Company Profile

07:37 EDT 22nd June 2018 | BioPortfolio

Alnylam Pharmaceuticals, a leader in RNAi therapeutics, is a biopharmaceutical company developing novel therapeutics based on a breakthrough in biology known as RNA interference, or RNAi; a discovery that enables the creation of a broad new class of human therapeutics. Using RNAi, Alnylam has built a product platform to develop a deep pipeline of drug products to treat a wide array of important diseases.
Founded by leading scientists who pioneered the discovery of RNAi, Alnylam is developing technology with the potential to specifically and potently silence disease-causing genes. RNA interference is a natural cellular process for selectively turning off the activity of genes by targeting RNA, the key intermediate between DNA and proteins. By harnessing this natural process, Alnylam is developing novel therapeutics that will utilize the natural RNAi mechanism to selectively suppress genes that produce proteins that play harmful roles in disease.

Alnylam is uniquely positioned to leverage the full potential of RNAi for therapeutic applications. Growing from its foundation as the world's first company focused on RNAi therapeutics, the company is built around the leading capabilities of its two operating units, Alnylam Pharmaceuticals of Cambridge, Massachusetts, and Alnylam Europe of Kulmbach, Germany. The company's leading position in the field of RNAi is supported by its preeminent founders and advisors and its strengths in fundamental patents, technology, and know-how relating to RNAi. These patents and patent applications broadly cover compositions, methods and uses of small interfering RNAs or siRNAs, the molecules that mediate RNAi. Alnylam's IP estate has been leveraged today with licenses to numerous companies for therapeutic and research market applications. Alnylam has assembled an experienced management team, strong financial resources, and world class collaborators to build a pipeline of RNAi therapeutics using both Direct RNAiTM and Systemic RNAiTM approaches. Alnylam has formed major alliances with Merck, Medtronic and Novartis.

Location

300 Third Street, 3rd Floor
Cambridge
2142
United States of America

Contact

Phone: 617-551-8200
Fax: 617-551-8101


News Articles [643 Associated News Articles listed on BioPortfolio]

Patisiran a launching pad for Alnylam venture into NASH research

Regeneron Pharmaceuticals and Alnylam Pharmaceuticals will collaborate to identify RNAi therapeutics…

Alnylam gains rights to Sanofi's transthyretin-mediated amyloidosis candidates

Sanofi and Alnylam Pharmaceuticals amended their 2012 deal to give Alnylam global development and marketing rights to transth -More- 

Alnylam Pharmaceuticals wartet auf die Zulassung

Alnylam Pharmaceuticals (WKN:A0CBCK), das kurz vor der Zulassung des ersten Medikaments stehts, meldete die Zahlen zum vierten Quartal und brachte die Investoren über seine RNAi-Medikamente auf den.....

U.S. biotech companies Alnylam, Dicerna settle trade secrets case

Dicerna Pharmaceuticals Inc on Friday said that it will pay $15 million plus stock to Alnylam Pharmaceuticals Inc to resolve a lawsuit claiming it stole trade secrets about gene-silencing technology u...

Regeneron, Alnylam partner to discover new treatments for NASH

Regeneron Pharmaceuticals and Alnylam Pharmaceuticals have entered into collaboration to identify RNAi therapeutics for the chronic liver disease nonalcoholic steatohepatitis (NASH) and potentially ot...

EMA accepts for review Alnylam's hereditary ATTR amyloidosis drug

Alnylam Pharmaceuticals' marketing application for patisiran, which is being developed as a treatment for patients with hered -More- 

Regeneron and Alnylam Team up to Tackle NASH Liver Disease

Regeneron Pharmaceuticals and Alnylam Pharmaceuticals signed a collaboration deal to identify RNAi therapies for nonalcoholic steatohepatitis (NASH) and other possibly related liver diseases.

Alnylam and Sanofi enter into strategic restructuring

Alnylam Pharmaceuticals, Inc. and Sanofi announced a strategic restructuring of their RNAi therapeutics alliance to streamline and optimize development and commercialization of certain products for th...

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PubMed Articles [134 Associated PubMed Articles listed on BioPortfolio]

With Alnylam's amyloidosis success, RNAi approval hopes soar.

Letter--Incorporating Real-World Evidence and Patient Value Criteria into Value-Based Frameworks for Relapsed/Refractory Multiple Myeloma.

Orlowski has received research funding from Amgen, BioTheryX, Bristol-Myers Squibb, Celgene Corporation, and Takeda Pharmaceuticals; honoraria from Amgen, Bristol-Myers Squibb, Celgene Corporation, Ja...

Genetics of familial hypercholesterolemia: a tool for development of novel lipid lowering pharmaceuticals?

Familial hypercholesterolemia is characterized by high LDL cholesterol and an elevated risk to develop coronary heart disease. Mutations in LDL receptor-mediated cholesterol uptake are the main cause ...

Post-production handling and administration of protein pharmaceuticals and potential instability issues.

The safety and efficacy of protein pharmaceuticals depend not only on biological activity, but also on purity levels. Impurities may be process related due to limitations in manufacturing, or product ...

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines and Pharmaceuticals.

Methods to incorporate deuterium and tritium atoms into organic molecules are valuable for medicinal chemistry. The prevalence of pyridines and diazines in pharmaceuticals means that new ways to label...

Clinical Trials [216 Associated Clinical Trials listed on BioPortfolio]

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic®20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sep...

Bioequivalence Study of Torrent Pharmaceuticals's Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic 20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sepa...

Study Comparing Citalopram Hydrobromide Tablets 40 mg (Torrent Pharmaceuticals Ltd) and RLD Tablets 40 mg (Manufactured By Forest Pharmaceuticals Inc, Missouri) in 24+2 Normal Healthy Male Subjects in Fed Condition

- Objective: - The objective of this study is to compare the rate and extent of absorption of the Test Product, Citalopram Hydrobromide 40 mg (Torrent Pharmaceutical Li...

Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Rosuvastatin Calcium Tablets Under Fed Conditions

Subjects to compare the single dose bioavailability of Torrent's Rosuvastatin Calcium Tablets 40 mg and Crestor® 40 mg Tablets of AstraZeneca Pharmaceuticals LP, USA. Dosing periods of st...

Cilostazol 50 mg Tablets Under Fasting Conditions

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Alnylam Europe AG

Alnylam ist ein biopharmazeutisches Unternehmen, das neuartige Therapeutika auf Basis der RNA-Interferenz (RNAi) entwickelt und hierbei eine führende Position inne hat. Die RNAi stellt einen Durchbru...

Alnylam Pharmaceuticals

Alnylam Pharmaceuticals, a leader in RNAi therapeutics, is a biopharmaceutical company developing novel therapeutics based on a breakthrough in biology known as RNA interference, or RNAi; a discovery ...

Alnylam Pharmaceuticals, Inc. and The Medicines Company

Alnylam Pharmaceuticals, Inc.

Alnylam is a biopharmaceutical company developing novel therapeutics based on RNA interference, or RNAi. The company is leading the translation of RNAi as a new class of innovative medicines with a ...

The Medicines Company and Alnylam Pharmaceuticals, Inc.

The Medicines Company is a biopharmaceutical company driven by an overriding purpose – to save lives, alleviate suffering and contribute to the economics of healthcare. The C...

More Information about "Alnylam Pharmaceuticals" on BioPortfolio

We have published hundreds of Alnylam Pharmaceuticals news stories on BioPortfolio along with dozens of Alnylam Pharmaceuticals Clinical Trials and PubMed Articles about Alnylam Pharmaceuticals for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Alnylam Pharmaceuticals Companies in our database. You can also find out about relevant Alnylam Pharmaceuticals Drugs and Medications on this site too.

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