Alnylam Europe AG Company Profile

11:01 EDT 19th September 2018 | BioPortfolio

Alnylam ist ein biopharmazeutisches Unternehmen, das neuartige Therapeutika auf Basis der RNA-Interferenz (RNAi) entwickelt und hierbei eine führende Position inne hat. Die RNAi stellt einen Durchbruch in der Biologie dar. Alnylams Produkt-Pipeline baut auf der RNAi als leistungsfähiger Plattform auf und hat zum Ziel, eine breitgefächerte neue Klasse von Therapeutika zur Behandlung einer Reihe von bedeutenden Erkrankungen hervorzubringen.
Alnylam wurde von führenden Wissenschaftlern gegründet, die zu den Pionieren bei der Entdeckung der RNAi gehören. Das Unternehmen setzt eine Technologie ein, mit der man sehr spezifisch und wirkungsvoll die Expression krankheitsverursachender Gene hemmen kann. Die RNAi ist ein natürlich vorkommender, zellulärer Prozess, durch den Gene spezifisch abgeschaltet werden können. Unter Ausnutzung dieses natürlichen Mechanismus entwickelt Alnylam neuartige Therapeutika, die selektiv solche Gene hemmen, deren Proteine eine schädliche Rolle bei der Krankheitsentstehung spielen.

Alnylam verfügt über hervorragende Voraussetzungen, um das Potenzial der RNAi für therapeutische Anwendungen voll auszuschöpfen. Alnylam ist das weltweit erste Unternehmen, das sich auf RNAi-Therapeutika spezialisiert hat. Es gründet sich auf die führende Expertise ihrer beiden operativen Einheiten, nämlich Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA, gegründet im Jahr 2002, und der Ribopharma AG, Kulmbach, Deutschland, gegründet im Jahr 2000. Letztere firmiert heute unter Alnylam Europe AG und ist ein Tochterunternehmen von Alnylam Pharmaceuticals.


Fritz-Hornschuch-Str. 9


Phone: 49 9221 82762-0
Fax: 49 9221 82762-99

News Articles [248 Associated News Articles listed on BioPortfolio]

RNAi Hits Europe as EMA Follows FDA, Approves Alnylam Drug

The first medicine that uses RNA interference, a method cells employ to mute a gene before it can make a harmful protein, has made its way to Europe. Three weeks after the FDA approved patisiran (Onpa...

Alnylam’s RNA therapy Onpattro bags EU nod

Alnylam’s RNAi therapeutic Onpattro has been approved for use in Europe to treat adults with polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis.

Alnylam Gets Landmark FDA OK For First-Ever RNAi Drug

[Updated at 3:25 pm ET, see below] Alnylam Pharmaceuticals made history this afternoon. The FDA has just approved Alnylam’s patisiran (Onpattro), making it the first medicine specifically cleared to...

Regeneron and Alnylam seek RNAi therapies for NASH

Regeneron and Alnylam are to research treatments for the chronic liver disease non-alcoholic steatohepatitis (NASH), under a new agreement. Alnylam specialises in treatments based around RNA interfer...

Alnylam's Onpattro cleared in Europe as ICER sets pricing battle

Regulators OK'd the first RNA interference therapy in Europe, but a new report finds the list price between 967% and 1,821% above value thresholds.

Alnylam taps Agilent for commercial API supply

The five-year deal will help support Alnylam's planned market launch of its RNAi therapeutic patisiran.

EC OKs Alnylam's hereditary transthyretin-mediated amyloidosis drug

Alnylam Pharmaceuticals' Onpattro, or patisiran, was approved by the European Commission as a treatment for adult patients wi -More- 

Agreement to differ

Approval of Alnylam’s RNAi therapy Onpattro starts a showdown in hATTR amyloidosis, where Alnylam’s legwork on a novel payment model could give it the edge.

Drugs and Medications [4 Associated Drugs and Medications listed on BioPortfolio]

Nizatidine [Dispensing Solutions Inc.]

Nizatidine Capsules USP Rx only


Akne-mycin (Erythromycin)

Manicure by opi - finishing butter [OPI Products, Inc]


Retavase [EKR Therapeutics, Inc.]

Retavase Reteplase, recombinant

PubMed Articles [344 Associated PubMed Articles listed on BioPortfolio]

Alnylam launches era of RNAi drugs.

The genomic history of southeastern Europe.

Farming was first introduced to Europe in the mid-seventh millennium bc, and was associated with migrants from Anatolia who settled in the southeast before spreading throughout Europe. Here, to unders...

Towards the risk of Yellow Fever transmission in Europe.

Yellow fever (YF) is an emerging expanding fatal arboviral disease that has been imported at least six times in Europe during the first half of 2018, while only seven travel-associated YF cases have b...

Infectious disease profiles of Syrian and Eritrean migrants presenting in Europe: A systematic review.

In the past decade, a large influx of migrants presented in Europe. Their country of origin was mainly either Syria or Eritrea. Public health institutions in host countries in Europe are challenged to...

The removal of DAA restrictions in Europe - one step closer to eliminating HCV as a major public health threat.

Of ∼10.2 million people with chronic HCV infection in Europe, most are living in Eastern Europe (6.7 million) followed by Western Europe (2.3 million) and Central Europe (1.2 million). HCV transmiss...

Clinical Trials [597 Associated Clinical Trials listed on BioPortfolio]

In-market Utilisation of Liraglutide Used for Weight Management in Europe: a Retrospective Medical Record Review Study

This study is conducted in Europe. The aim of this study is to investigate usage of liraglutide for weight management in clinical practice.

Description/Characterisation of Asthmatics Eligible for Biologic Therapy Referral in Prim. and Sec. Care in Europe

This is a multi-country, multicentre, observational cross-sectional one-visit study of patients with severe asthma in primary and secondary care settings in Europe

RITE-EUROPE (Radiofrequency-Induced Thermochemotherapy Effect-EUROPE)

This multicenter, prospective, single-arm, phase 3 study will assess the proportion of disease-free patients, starting from administration of the first study treatment to at least 12-month...

EUROpE-RSI (EURopean Online Evaluation RSI Study)

The investigators want to identify and show differences in standards and procedures of in-hospital rapid sequence induction by collecting data with an online survey for anaesthetist in Eur...

A Study Measuring Quality of Life, Treatment Preference and Satisfaction of ADPKD Patients in Europe

This is a prospective, non-interventional study (NIS) measuring health-related quality of life (HRQoL), treatment satisfaction, and other patient-reported outcomes (PROs) of ADPKD patients...

Companies [849 Associated Companies listed on BioPortfolio]

Alnylam Europe AG

Alnylam ist ein biopharmazeutisches Unternehmen, das neuartige Therapeutika auf Basis der RNA-Interferenz (RNAi) entwickelt und hierbei eine führende Position inne hat. Die RNAi stellt einen Durchbru...

Alnylam Pharmaceuticals

Alnylam Pharmaceuticals, a leader in RNAi therapeutics, is a biopharmaceutical company developing novel therapeutics based on a breakthrough in biology known as RNA interference, or RNAi; a discovery ...

Alnylam Pharmaceuticals, Inc.

Alnylam is a biopharmaceutical company developing novel therapeutics based on RNA interference, or RNAi. The company is leading the translation of RNAi as a new class of innovative medicines with a ...

Alnylam Pharmaceuticals, Inc. and The Medicines Company

Europe Unlimited

Europe Unlimited profiles and connects the community of Europe’s best tech entrepreneurs and international capital through research, networking events and consulting. As such, we are in a position t...

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