Applied Molecular Evolution Company Profile

14:35 EDT 22nd September 2018 | BioPortfolio

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME’s principal focus has been on applying its proprietary AMEsystem™ technology platform to the full range of protein therapeutic candidates including antibodies, cytokines, hormones and enzymes to develop novel human biotherapeutic candidates.
Since February 2004, AME has been a wholly-owned subsidiary of Eli Lilly and Company and is an integral part of Lilly’s research organization. Lilly, a leading innovation-driven corporation is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs.

While geographically separate, AME works closely with Lilly colleagues in Indianapolis and around the world, sharing a corporate legacy of integrity and commitment to quality that spans more than a century.


3520 Dunhill street
San Diego
United States of America


Phone: 858.597.4990
Fax: 858.597.4950

News Articles [1050 Associated News Articles listed on BioPortfolio]

Applied BioCode's molecular Dx platform, GI pathogen panel win EU nod

European regulators gave Applied BioCode CE mark approval for its BioCode MDx 3000 high-volume, automated PCR-based molecular -More- 

The evolution of testes

(Max-Planck-Gesellschaft) Molecular vestiges resolve the controversial evolution of the testicular position in mammals.

Applied DNA And Colorcon Sign Definitive Agreements For Molecular Tagging

NewsThe agreements include milestone payments and long-term licensing royalties to be paid to Applied DNA following sales.Contributed Au

Virus found to adapt through newly discovered path of evolution

Biologists have discovered evidence for a new path of evolution, and with it a deeper understanding of how quickly organisms such as viruses can adapt to their environment. The researchers say their f...

Is molecular evolution faster in the tropics?

Publisher Correction: A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

Capsule maker ups track and trace with molecular tagging

ACG says adding Applied DNA Sciencesâ molecular tagging and authentication technology to its capsule products will increase supply chain security.

Maxygen Liceses Directed Evolution Technology from CalTech

Maxygen, Inc. (Redwood City, CA) has obtained an exclusive worldwide license from the California Institute of Technology (Pasadena) for the Staggered Extension Process (StEP) directed evolution techno...

Drugs and Medications [395 Associated Drugs and Medications listed on BioPortfolio]

Soleo organics sunscreen [Skin Elements USA, LLC]

Soleo Organics

Xolegel [Stiefel Laboratories Inc]


Sun savvy solar shield [APPLIED SKIN TECHNOLOGY LLC]


U40 [Kylemore Pharmaceuticals, LLC]

U40 Foam

Mometasone furoate ointment usp, 0.1% [E. FOUGERA and CO.]


PubMed Articles [2632 Associated PubMed Articles listed on BioPortfolio]

Neutral theory and the somatic evolution of cancer.

Kimura's neutral theory argued that positive selection was not responsible for an appreciable fraction of molecular substitutions. Correspondingly, quantitative analysis reveals that the vast majority...

Neutral theory and phenotypic evolution.

Although the neutral theory of molecular evolution was proposed to explain DNA and protein sequence evolution, in principle it could also explain phenotypic evolution. Nevertheless, overall, phenotype...

Protein Evolution is Potentially Governed by Protein Stability: Directed Evolution of an Esterase from the Hyperthermophilic Archaeon Sulfolobus tokodaii.

The study of evolution is important to understand biological phenomena. During evolutionary processes, genetic changes confer amino acid substitutions in proteins, resulting in new or improved functio...

Understanding dengue virus evolution to support epidemic surveillance and counter-measure development.

Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globali...

Different genomic changes underlie adaptive evolution in populations of contrasting history.

Clinical Trials [3227 Associated Clinical Trials listed on BioPortfolio]

Co-adaptation Between HIV and CD8 Cellular Immunity

Our objective here is to characterize the viral evolution and viral factors determining HIV virulence, the evolution of the HIV reservoir in PBMC and the co-evolution of anti-HIV CD8 T cel...

A Prospective Trial to Study the Evolution of Clonal Architecture of Tumors From Patients Treated With Molecular Targeted Agents

This is a prospective study to identify molecular mechanisms of acquired resistance to targeted therapies in patients with unresectable or metastatic cancer. This is a protocol to study c...

Prospective System Analysis of the Seasonal Influenza Virus Transmissions and Evolution in the City of Basel Basel

The project aims to use epidemiological tools to understand the transmission and evolution of influenza viruses at an individual and population level within a small-scale city (Basel) thro...

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

The relationship between shock, ischemia and reperfusion (I/R) injury, hemodynamic instability, systemic inflammatory response syndrome and multiorgan failure has been extensively investig...

Analysis of Clinical and Molecular Genetic Data Influencing the Evolution and Response to Therapy of ADPKD Patients (Autosomal Dominant Polycystic Kidney Disease)

Genkyst is a regional cohort involving up to nephrologists working in private and public nephrology centers in the West of France. It registers clinical and molecular genetic data of all c...

Companies [1342 Associated Companies listed on BioPortfolio]

Applied Molecular

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietar...

Applied Molecular Evolution

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME...

Novasite Pharmaceuticals, Inc

Novasite is a drug discovery company using structure-function relationships in validated G protein coupled receptor targets to find better GPCR modulating drugs.Novasite began as a majority-owned subs...

Lilly Corporate Center

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve <!--LGfEGNT2Lhm-->healthcare by discovering, optimizing and developing human biotherapeutics. ...

Applied DNA Sciences Inc.

Applied DNA is a provider of molecular technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping and DNA mass production fo...

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We have published hundreds of Applied Molecular Evolution news stories on BioPortfolio along with dozens of Applied Molecular Evolution Clinical Trials and PubMed Articles about Applied Molecular Evolution for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Applied Molecular Evolution Companies in our database. You can also find out about relevant Applied Molecular Evolution Drugs and Medications on this site too.

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