Applied Molecular Evolution Company Profile

00:15 EST 19th December 2018 | BioPortfolio

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME’s principal focus has been on applying its proprietary AMEsystem™ technology platform to the full range of protein therapeutic candidates including antibodies, cytokines, hormones and enzymes to develop novel human biotherapeutic candidates.
Since February 2004, AME has been a wholly-owned subsidiary of Eli Lilly and Company and is an integral part of Lilly’s research organization. Lilly, a leading innovation-driven corporation is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs.

While geographically separate, AME works closely with Lilly colleagues in Indianapolis and around the world, sharing a corporate legacy of integrity and commitment to quality that spans more than a century.


3520 Dunhill street
San Diego
United States of America


Phone: 858.597.4990
Fax: 858.597.4950

News Articles [1064 Associated News Articles listed on BioPortfolio]

Molecular Phylogenetics: A New Way to Tell the Story of Evolution

The new science of molecular phylogenetics tells the story of evolution with no need to consult the fossil record. It has produced some surprises, including a whole new domain of life, the archaea.

The evolution of testes

(Max-Planck-Gesellschaft) Molecular vestiges resolve the controversial evolution of the testicular position in mammals.

Skin game

(Molecular Biology and Evolution (Oxford University Press)) Medical University of Vienna professor Leopold Eckhart and colleagues have performed one of the largest comparative genomic studies to help ...

Nobel in Chemistry Awarded for Directed Evolution of Enzymes and Antibodies

This year, the Nobel Prize in Chemistry recognizes that when scientists need to improve enzymes and antibodies, scientists sometimes find that the most rational thing they can do is abandon rational d...

ASU research graces cover of ACS journal

(Arizona State University) Gary Moore, an assistant professor in the School of Molecular Sciences and a researcher with the Biodesign Center for Applied Structural Discovery, and his team won the cove...

Nobel for Chemistry Goes to Trio Who Harnessed Molecular Evolution

NewsThe artificial selection of molecules in the laboratory—harnessing evolution to produce targeted enzymes and antibodies—is the revolution that led to this year’s Nobel Prize for Chemistry.

Fruit fly study challenges theories on evolution and high-carb diets

(University of New South Wales) UNSW fruit fly research challenges neutral theory of molecular evolution and suggests one day we may be prescribed diets according to our genes.

Nobel Prize For Chemistry Goes To Three Scientists For Harnessing Sped-Up Evolution For Best-Selling Drug, Biofuels

The winners -- Frances Arnold of the California Institute of Technology, George Smith of the University of Missouri and Gregory Winter of the MRC molecular biology lab in England -- “have taken cont...

Drugs and Medications [395 Associated Drugs and Medications listed on BioPortfolio]

Soleo organics sunscreen [Skin Elements USA, LLC]

Soleo Organics

Xolegel [Stiefel Laboratories Inc]


Sun savvy solar shield [APPLIED SKIN TECHNOLOGY LLC]


U40 [Kylemore Pharmaceuticals, LLC]

U40 Foam

Mometasone furoate ointment usp, 0.1% [E. FOUGERA and CO.]


PubMed Articles [2617 Associated PubMed Articles listed on BioPortfolio]

A Report by the Editor-in-Chief for Molecular Biology and Evolution (MBE), Volume 34.

Evolution of Sex-Biased Gene Expression and Dosage Compensation in the Eye and Brain of Heliconius Butterflies.

The diversity, evolution and epidemiology of plant viruses: A phylogenetic view.

During the past four decades, the scientific community has seen an exponential advance in the number, sophistication, and quality of molecular techniques and bioinformatics tools for the genetic chara...

Spermatogenesis and the Evolution of Mammalian Sex Chromosomes.

Developmental constraint and sexual conflict shape the evolution of heteromorphic sex chromosomes. These contrasting forces are perhaps strongest during spermatogenesis in species with XY males. In th...

Homology in Amniote Brain Evolution: The Rise of Molecular Evidence.

Clinical Trials [3415 Associated Clinical Trials listed on BioPortfolio]

Sweden Cancerome Analysis Network - Breast Recurrence (SCAN-B-rec)

Prospective multicenter observational study to assess molecular drivers of metastatic breast cancer and disease evolution upon therapeutic pressure. The main aim is to develop and validat...

Visual Study of Molecular Genotype in Glioma Evolution

The key molecular changes in the progression of glioma are closely related to tumor heterogeneity, pathological grade, precision treatment and prognosis of glioma. At present, a visually q...

Co-adaptation Between HIV and CD8 Cellular Immunity

Our objective here is to characterize the viral evolution and viral factors determining HIV virulence, the evolution of the HIV reservoir in PBMC and the co-evolution of anti-HIV CD8 T cel...

A Prospective Trial to Study the Evolution of Clonal Architecture of Tumors From Patients Treated With Molecular Targeted Agents

This is a prospective study to identify molecular mechanisms of acquired resistance to targeted therapies in patients with unresectable or metastatic cancer. This is a protocol to study c...

Prospective System Analysis of the Seasonal Influenza Virus Transmissions and Evolution in the City of Basel Basel

The project aims to use epidemiological tools to understand the transmission and evolution of influenza viruses at an individual and population level within a small-scale city (Basel) thro...

Companies [1354 Associated Companies listed on BioPortfolio]

Applied Molecular

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietar...

Applied Molecular Evolution

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME...

Novasite Pharmaceuticals, Inc

Novasite is a drug discovery company using structure-function relationships in validated G protein coupled receptor targets to find better GPCR modulating drugs.Novasite began as a majority-owned subs...

Lilly Corporate Center

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve <!--LGfEGNT2Lhm-->healthcare by discovering, optimizing and developing human biotherapeutics. ...

Applied DNA Sciences Inc.

Applied DNA is a provider of molecular technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping and DNA mass production fo...

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We have published hundreds of Applied Molecular Evolution news stories on BioPortfolio along with dozens of Applied Molecular Evolution Clinical Trials and PubMed Articles about Applied Molecular Evolution for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Applied Molecular Evolution Companies in our database. You can also find out about relevant Applied Molecular Evolution Drugs and Medications on this site too.

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