Applied Molecular Evolution Company Profile

20:21 EDT 17th June 2018 | BioPortfolio

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME’s principal focus has been on applying its proprietary AMEsystem™ technology platform to the full range of protein therapeutic candidates including antibodies, cytokines, hormones and enzymes to develop novel human biotherapeutic candidates.
Since February 2004, AME has been a wholly-owned subsidiary of Eli Lilly and Company and is an integral part of Lilly’s research organization. Lilly, a leading innovation-driven corporation is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs.

While geographically separate, AME works closely with Lilly colleagues in Indianapolis and around the world, sharing a corporate legacy of integrity and commitment to quality that spans more than a century.


3520 Dunhill street
San Diego
United States of America


Phone: 858.597.4990
Fax: 858.597.4950

News Articles [990 Associated News Articles listed on BioPortfolio]

Applied BioCode's molecular Dx platform, GI pathogen panel win EU nod

European regulators gave Applied BioCode CE mark approval for its BioCode MDx 3000 high-volume, automated PCR-based molecular -More- 

Applied DNA And Colorcon Sign Definitive Agreements For Molecular Tagging

NewsThe agreements include milestone payments and long-term licensing royalties to be paid to Applied DNA following sales.Contributed Au

Collaboration Aims To Thwart Counterfeits With Molecular Tagging Of Capsules

NewsApplied DNA Sciences and ACG have signed a memorandum of understanding that will allow ACG to utilize Applied DNA’s molecular tagging and authentication technologies to develop molecularly-tagge...

Applied DNA & ACG Sign Agreement

ACG will use Applied DNA's SigNature molecular tagging & authentication technologies to develop empty hard-shell capsules

Cockroach Ancient Geographic and Genomic History Traced Back to Last Supercontinent

NewsResearchers have used the latest in genomic data to gain the most detailed information yet of the evolutionary history of cockroaches.

Convergent evolution of gene regulation in humans and mice

Organisms that aren't closely related may evolve similar traits as they adapt to similar challenges. It's called convergent evolution, and familiar examples include the wings of birds, bats, and insec...

New insights into human evolution

The evolution of human biology should be considered part and parcel with the evolution of humanity itself, proposes an assistant professor of biological sciences. She explores an interdisciplinary app...

Study finds convergent evolution of gene regulation in humans and mice

(University of California - Santa Cruz) Organisms that aren't closely related may evolve similar traits as they adapt to similar challenges. It's called convergent evolution, and familiar examples inc...

Drugs and Medications [395 Associated Drugs and Medications listed on BioPortfolio]

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Soleo Organics

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Sun savvy solar shield [APPLIED SKIN TECHNOLOGY LLC]


U40 [Kylemore Pharmaceuticals, LLC]

U40 Foam

Mometasone furoate ointment usp, 0.1% [E. FOUGERA and CO.]


PubMed Articles [2642 Associated PubMed Articles listed on BioPortfolio]

Neutral theory and the somatic evolution of cancer.

Kimura's neutral theory argued that positive selection was not responsible for an appreciable fraction of molecular substitutions. Correspondingly, quantitative analysis reveals that the vast majority...

Neutral theory and phenotypic evolution.

Although the neutral theory of molecular evolution was proposed to explain DNA and protein sequence evolution, in principle it could also explain phenotypic evolution. Nevertheless, overall, phenotype...

Protein Evolution is Potentially Governed by Protein Stability: Directed Evolution of an Esterase from the Hyperthermophilic Archaeon Sulfolobus tokodaii.

The study of evolution is important to understand biological phenomena. During evolutionary processes, genetic changes confer amino acid substitutions in proteins, resulting in new or improved functio...

Understanding dengue virus evolution to support epidemic surveillance and counter-measure development.

Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological context of globali...

Different genomic changes underlie adaptive evolution in populations of contrasting history.

Clinical Trials [3019 Associated Clinical Trials listed on BioPortfolio]

Co-adaptation Between HIV and CD8 Cellular Immunity

Our objective here is to characterize the viral evolution and viral factors determining HIV virulence, the evolution of the HIV reservoir in PBMC and the co-evolution of anti-HIV CD8 T cel...

A Prospective Trial to Study the Evolution of Clonal Architecture of Tumors From Patients Treated With Molecular Targeted Agents

This is a prospective study to identify molecular mechanisms of acquired resistance to targeted therapies in patients with unresectable or metastatic cancer. This is a protocol to study c...

Prospective System Analysis of the Seasonal Influenza Virus Transmissions and Evolution in the City of Basel Basel

The project aims to use epidemiological tools to understand the transmission and evolution of influenza viruses at an individual and population level within a small-scale city (Basel) thro...

Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock

The relationship between shock, ischemia and reperfusion (I/R) injury, hemodynamic instability, systemic inflammatory response syndrome and multiorgan failure has been extensively investig...

Analysis of Clinical and Molecular Genetic Data Influencing the Evolution and Response to Therapy of ADPKD Patients (Autosomal Dominant Polycystic Kidney Disease)

Genkyst is a regional cohort involving up to nephrologists working in private and public nephrology centers in the West of France. It registers clinical and molecular genetic data of all c...

Companies [1327 Associated Companies listed on BioPortfolio]

Applied Molecular

Applied Molecular Evolution, Inc. (AME) is a leader in the application of directed molecular evolution to improve healthcare by optimizing and developing human biotherapeutics. AME uses its proprietar...

Applied Molecular Evolution

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME...

Novasite Pharmaceuticals, Inc

Novasite is a drug discovery company using structure-function relationships in validated G protein coupled receptor targets to find better GPCR modulating drugs.Novasite began as a majority-owned subs...

Lilly Corporate Center

Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve <!--LGfEGNT2Lhm-->healthcare by discovering, optimizing and developing human biotherapeutics. ...

Applied BioCode, Inc.

Applied BioCode, Inc. is a privately held biotechnology company with headquarters located in Santa Fe Springs, California. Applied BioCode develops, manufactures, and markets high...

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We have published hundreds of Applied Molecular Evolution news stories on BioPortfolio along with dozens of Applied Molecular Evolution Clinical Trials and PubMed Articles about Applied Molecular Evolution for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Applied Molecular Evolution Companies in our database. You can also find out about relevant Applied Molecular Evolution Drugs and Medications on this site too.

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