The Binding Site Inc Company Profile

05:48 EST 22nd November 2017 | BioPortfolio

We at are dedicated to supplying quality purified proteins and biologicals to the Biotechnology Industry. We have been providing these products to the Biotechnology industry since 1988 and have recently expanded both our product line and our team of experienced, reliable professionals.


5889 Oberlin Drive Suite 101
San Diego
United States of America


Phone: 858-453-9177
Fax: 858-453-9189

News Articles [421 Associated News Articles listed on BioPortfolio]

New Recombinant Parvovirus Antigens Now Available from Binding Site

Binding Site’s Immunologicals Group is pleased to announce the addition of eight new recombinant antigens to its broad offering of products for in-vitro diagnostic (IVD) manufacturing and resear...

Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists

PCSK9 binds to and promotes degradation of LDLR, thus regulating serum levels of LDL. An accessible groove in PCSK9, adjacent to the LDLR-binding site, can be targeted by peptides that disrupt the LDL...

Binding Site launches new antigens and antibodies for infectious/contagious diseases

The Immunologicals Group of The Binding Site is pleased to announce the launch of a number of new monoclonal antibodies and recombinant antigens focused on a variety of infectious/contagious disease s...

Researchers uncover new molecular binding site that can influence electrical impulses in nerves

Researchers at Linköping University in Sweden have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves.

Model This?

Via Ash Jogalekar on Twitter, I came across this new paper from researchers at AstraZeneca (and collaborators in Sweden, the UK, and Denmark) on the synthesis and activity of some plasmin inhibitors....

De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy

The first demonstration of a protein designed entirely from first principles that binds a small-molecule cofactor in a precisely predetermined orientation has now been described. The design method uti...

Zinc-binding is vital for regulating pH levels in the brain

Researchers in Oslo, Norway, have discovered that Zinc-binding plays an important role in the sensing and regulation of pH in the human brain. The findings come as one of the first studies that dire...

Binding Site Expands Monoclonal Antibody Product Offerings

Availability of these products will enhance the needs of biopharmaceutical, clinical, and life science researchers, along with IVD manufacturer

PubMed Articles [2720 Associated PubMed Articles listed on BioPortfolio]

Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates plasma LDL cholesterol (LDL-c) levels by promoting the degradation of liver LDL receptors (LDLRs). Antibodies that inhibit PCSK9 binding...

Non-canonical Binding Site for Bacterial Initiation Factor 3 on the Large Ribosomal Subunit.

Canonical translation initiation in bacteria entails the assembly of the 30S initiation complex (IC), which binds the 50S subunit to form a 70S IC. IF3, a key initiation factor, is recruited to the 30...

Quantitative specificity of STAT1 and several variants.

The quantitative specificity of the STAT1 transcription factor was determined by measuring the relative affinity to hundreds of variants of the consensus binding site including variations in the lengt...

Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A.

We have previously identified a cyclic peptide called meditope which binds to the central cavity of the Fab portion of cetuximab and shown that this peptide binding site can be grafted, or 'meditope-e...

Mapping the binding site for escitalopram and paroxetine in the human serotonin transporter using genetically-encoded photocrosslinkers.

In spite of the important role of the human serotonin transporter (hSERT) in depression treatment, the molecular details of how antidepressant drugs bind are still not completely understood, in partic...

Clinical Trials [1606 Associated Clinical Trials listed on BioPortfolio]

Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH Campus

Plasma histidine-rich glycoprotein (HRG) binds to platelets in the presence of zinc (1). This binding is totally blocked by a monoclonal antibody directed against platelet membrane CD36. ...

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

This clinical trial studies the side effects of 18F-alphavbeta6-binding-peptide and how well it works in imaging patients with primary or cancer that has spread to the breast, colorectal, ...

Study of the Role of Soluble Inhibitor of Interleukin 22, Interleukin 22 Binding Protein (IL-22BP), in Chronic Inflammatory Bowel Disease

IL-22 is an IL-10 family cytokine that plays major actions to increase intestinal epithelial barrier function and regeneration during experimental colitis. IL-22 binding protein is a small...

Specific Effects of Escitalopram on Neuroendocrine Response

Citalopram, a selective serotonin reuptake inhibitor (SSRI), is used as a neuroendocrine probe in human subjects to assess serotonin (5-hydroxytryptamine; 5-HT) function as reflected in pr...

Study on Mannan Binding Lectin (MBL) Substitution in MBL-Deficient Children With Chemotherapy-Induced Neutropenia

The pharmacokinetics, and clinical and biological effects of MBL replacement therapy in MBL-deficient children during chemotherapy-induced neutropenia were studied.

Companies [988 Associated Companies listed on BioPortfolio]

Binding Site

Binding Site is committed to improving patient lives worldwide through education, collaboration and innovation. The company focuses on research, development, manufacture and distr...

The Binding Site Group

Sangamo BioSciences, Inc.

Sangamo BioSciences, Inc. is focused on the research and development of novel DNA-binding proteins for therapeutic gene regulation and modification. The most advanced ZFP Therapeutic(TM) development p...

BioHesion Inc.

BioHesion is pleased to offer a custom cloning and protein expression service. We recognize a large number of applications exist for Gold Binding Fusion proteins. We believe that our technology provid...

Civilized Software, Inc.

MLAB is an ideal tool for mathematical and statistical exploration, and for solving simulation and modeling problems such as chemical kinetics, pharmacological compartmental models, multiple site liga...

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