BioStratum Incorporated Company Profile

21:46 EST 11th December 2018 | BioPortfolio

BioStratum is focused on the discovery, development and commercialization of novel therapeutic agents for the treatment of diabetes and diabetic complications. BioStratum's pipeline is led by Pyridorin™ a small molecule drug for the treatment of diabetic kidney disease, followed by pre-clinical compounds that will treat other diabetic complications and cancer. Pyridorin has been granted Fast Track status by the FDA and has been shown to be safe and potentially effective in treating diabetic patients with kidney disease. In our recently completed Phase II studies, Pyridorin decreased in a statistically significant manner the rate of rise in serum creatinine, a leading indicator of diabetic kidney disease progression. We believe these results validate BioStratum's approach to treating diabetic complications by inhibiting the formation of harmful advanced glycation endproducts or "AGEs", and support the aggressive ongoing campaign to identify and develop second-generation AGE inhibitors


2300 Englert Drive; Suite G
North Carolina
United States of America


Phone: 919-433-1000
Fax: 919-433-1010

News Articles [1 Associated News Articles listed on BioPortfolio]

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Companies [38 Associated Companies listed on BioPortfolio]

BioStratum Incorporated

BioStratum is focused on the discovery, development and commercialization of novel therapeutic agents for the treatment of diabetes and diabetic complications. BioStratum's pipeline is led by Pyridori...


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Drug Discovery
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...

Nephrology - kidney function
Nephrology is a specialty of medicine and pediatrics that concerns itself with the study of normal kidney function, kidney problems, the treatment of kidney problems and renal replacement therapy (dialysis and kidney transplantation). Systemic conditions...

Diabetes is a lifelong condition that causes a person's blood sugar level to become too high. The two main types of diabetes are: type 1 diabetes type 2 diabetes In the UK, diabetes affects approximately 2.9 million people. There are a...

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