BioTechNews Denmark Company Profile

09:05 EDT 21st March 2018 | BioPortfolio

TopoTarget and CuraGen Announce Initiation of NCI-sponsored Phase II Clinical Trial with PXD101 for MesotheliomaTopoTarget A/S and CuraGen Corporation announced today the initiation of patient dosing in a Phase II clinical trial evaluating the activity of PXD101, a small molecule histone deacetylase (HDAC) inhibitor, for the treatment of mesothelioma. This trial is being sponsored by the National Cancer Institute (NCI) under a Clinical Trials Agreement.
The Phase II clinical trial is an open-label study being led by Suresh Ramalingam, M.D., Assistant Professor of Medicine at the University of Pittsburgh School of Medicine, in Pittsburgh, PA, USA. Patients with unresectable malignant pleuralm esothelioma, w,ho have failed one prior line of chemotherapy, will be enrolled and receive PXD101by intravenous infusion every three weeks. The primary endpoint for the study is response rate, with secondary endpoints evaluating safety and measuring both the time to treatment failure and survival. A total of approximately 37 patients are expected to be enrolled into this study at multiple sites across the United States.


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News Articles [143 Associated News Articles listed on BioPortfolio]

Cohaesio to Become a Part of Sentia Group, Consolidating Its Market Position in Denmark

COPENHAGEN, Denmark, March 5, 2018/PRNewswire/ -- Cohaesio, a leading IT outsourcer in Denmark, and Sentia Group, a European leader in business-critical application Read more...

Male trout are now real males again

(University of Southern Denmark) The media has been telling us about feminised male fish for decades, but now researchers at SDU announce that this feminisation has completely disappeared in certain p...

Huawei Partners with Intel to Build a Supercomputing Cluster for Technical University of Denmark(DTU)

SHENZHEN, China, Nov. 2, 2017 /PRNewswire/ -- For almost two centuries DTU, Technical University of Denmark, has been dedicated to fulfilling the vision of H.C. Orsted - the father of electromagne...

Maize fields entice geese to winter in Denmark

(Aarhus University) More and more geese remain in Denmark for the winter. They forage in the growing number of maize fields all over the country. Researchers warn that, in the long term, the many gees...

Popular blood pressure medicine linked with increased risk of skin cancer

(University of Southern Denmark Faculty of Health Sciences) Recently published research from the University of Southern Denmark and the Danish Cancer Society shows a connection between one of the most...

Popular Blood Pressure Med Linked To Increased Risk Of Skin Cancer

NewsRecently published research from the University of Southern Denmark and the Danish Cancer Society shows a connection between one of the most common medications for hypertension and skin cancer.

H. Lundbeck A/S: Lundbeck increases its share capital by 116,330 shares (0.0585 % of outstanding shares) as a result of exercise of employee warrants

Valby, Denmark, 2017-11-21 11:28 CET (GLOBE NEWSWIRE) -- Valby, Denmark, 21 November 2017 - H. Lundbeck A/S (Lundbeck) today announced that it has decided to increase its share capital by DKK 581,6...

H. Lundbeck A/S: Transactions with shares and linked securities in H. Lundbeck A/S made by executives and their closely associated parties

Valby, Denmark, 2017-11-17 18:55 CET (GLOBE NEWSWIRE) -- Valby, Denmark, 17 November 2017 - H. Lundbeck A/S (Lundbeck) hereby publishes and reports transactions made by executives and persons close...

Drugs and Medications [3 Associated Drugs and Medications listed on BioPortfolio]

Total truth [Ole Henriksen of Denmark]

Total Truth Eye Cream SPF 15

Baza protect [Coloplast Manufacturing US, LLC]

Baza Protect Skin ProtectantMoisture Barrier Cream

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Protect the Truth SPF 50

PubMed Articles [84 Associated PubMed Articles listed on BioPortfolio]


The authors would like to correct the error in the publication of the original article with the inclusion of an additional author (Dr. Henrik Nielsen). The corrected detail is published with this erra...

Adaptation of a tool to assess non-technical skills of scrub practitioners in Denmark.

The aim of this study was to adapt the Scottish tool, Scrub Practitioners List of Intraoperative Non-Technical Skills, to Danish organisation and culture. With an explorative and qualitative approach,...

Mood Disorders and Risk of Herpes Zoster in Two Population-Based Case-Control Studies in Denmark and the United Kingdom.

We examined the association between mood disorders and risk of herpes zoster in two case-control studies using data from nationwide Danish registries and practices in the UK Clinical Practice Research...

Cost analysis of bariatric surgery in Denmark made with a decision-analytic model.

Bariatric surgery offers effective obesity treatment. The aim of this study was to evaluate the cost-effectiveness of bariatric surgery in Denmark from a third-party payer perspective in the mid- (ten...

Association of common comorbidities with osteonecrosis: a nationwide population-based case-control study in Denmark.

To examine recent time trends in the incidence of osteonecrosis (ON) in Denmark and to investigate different common comorbidities association with ON in a population-based setting.

Clinical Trials [166 Associated Clinical Trials listed on BioPortfolio]

Central Nervous System Infections in Denmark

The Danish Study Group of Infections of the Brain is a collaboration between all departments of infectious diseases in Denmark. The investigators aim to monitor epidemiological trends in c...

Health-Related Quality of Life in Upper Secondary Schools in Denmark

Measuring Quality of Life in an upper secondary school in Denmark

Post ICU Follow up: A Questionnaire Survey of Aftercare in Denmark

This study aims to investigate current aftercare activities in Denmark after intensive care unit (ICU) treatment. The hypothesis is that a large number of hospitals offer aftercare, and th...

The Danish General Rural Population Study

The study is a epidemiological, cross-sectional study in a mainly rural area of Denmark in Denmark. Life expectancy is shorter, morbidity is higher, and social problems more prevalent than...

Long-term Consequences of Necrotizing Enterocolitis in the Newborn Period

Aim The aim of this study is to determine consequences at school age of the diagnosis of NEC in the neonatal period. Methods This is a case-control study, with case-group be...

Companies [112 Associated Companies listed on BioPortfolio]

Invest in Denmark, Ministry of Foreign Affairs of Denmark


PBN MEDICALS Denmark A/S is a company in the international InterV group, owned by Canadian Angiotech Pharmaceuticals Inc., Vancouver. InterV is the combined name for the PBN MEDICALS (Denmark) and MD ...

Venture Cup Danmark

Venture Cup Denmark is a yearly held professional business plan competition. Teams must have at least one person related to a university or business school in Denmark [as a student at bachelor level,...

BioTechNews Denmark

TopoTarget and CuraGen Announce Initiation of NCI-sponsored Phase II Clinical Trial with PXD101 for MesotheliomaTopoTarget A/S and CuraGen Corporation announced today the initiation of patient dosing ...


The Science Park Association in Denmark is an organization of science parks and innovative incubators in Denmark. The Association is a nationwide forum for exchange of experience and opinion formation...

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