Cortical Pty Ltd Company Profile

22:01 EDT 21st June 2018 | BioPortfolio

Inflammatory diseases can be successfully targeted with anti-cytokine therapies. Small molecule cytokine antagonists have never previously been developed, but may provide a valuable combination of effectiveness in treatment, potential oral administration, and a cost which may allow more patients to receive the treatment. In addition such molecules have the potential for formulation for use as a topical treatment or as an aerosol.


27-31 Wright StClayton


Phone: 613 9594 7300
Fax: 613 9594 7311

News Articles [52 Associated News Articles listed on BioPortfolio]

Cortical bone loss may contribute to fractures in post-menopausal women

A new study in Journal of Bone and Mineral Research looked at the relative contributions of the two types of bone-cortical, or compact bone, and trabecular, or spongy bone-to total bone loss.

Relapse in Major Depression Linked to Brain Cortical Changes

THURSDAY, March 29, 2018 -- For patients with major depressive disorder (MDD), relapse is associated with brain cortical changes over two years, according to a study published online March 28 in JAMA ...

A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study

The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer’s disease.

Kessler Foundation receives grant to study cortical changes in youth with brain injury

(Kessler Foundation) Drs. Kiran Karunakaran and Karen Nolan have won a $35,000 grant from New Jersey Health Foundation to study the cortical changes in children and young adults with lower extremity m...

First patient receives Orion cortical visual prosthesis

The first human patient was implanted with the Orion cortical visual prosthesis system, according to a press release from Second Sight Medical Products.The implantation was completed by Nader Pouratia...

Developmental diversification of cortical inhibitory interneurons

Profiling changes in cortical astroglial cells following chronic stress

Control of synaptic plasticity in deep cortical networks

Drugs and Medications [20 Associated Drugs and Medications listed on BioPortfolio]

Zonegran [Eisai Inc.]

ZONEGRAN (zonisamide) capsulesRx Only

Zonisamide capsules [ALPHAPHARM PARTY LTD]

Zonisamide Capsules

Lamotrigine tablets (chewable, dispersible) [Dr. Reddy's Laboratories Ltd]

Lamotrigine Tablets (chewable, dispersible)

Lamotrigine [American Health Packaging]


Zonisamide [AvPAK]

Zonisamide 100mg

PubMed Articles [685 Associated PubMed Articles listed on BioPortfolio]

PET staging of amyloidosis using striatum.

Amyloid PET data are commonly expressed as binary measures of cortical deposition. However, not all individuals with high cortical amyloid will experience rapid cognitive decline. Motivated by postmor...

Deterioration of Cortical Bone Microarchitecture: Critical Component of Renal Osteodystrophy Evaluation.

Cortical bone is a significant determinant of bone strength and its deterioration contributes to bone fragility. Thin cortices and increased cortical porosity have been noted in patients with chronic ...

New developments in understanding focal cortical malformations.

Focal cortical dysplasias (FCDs) represent common cortical malformations that are frequently associated with epilepsy. They have so far not been well understood in terms of their molecular pathogenesi...

A Multimodal Approach For Radical Excision Of Focal Cortical Dysplasia By Combining Advanced Mri Data To Intraoperative Ultrasound, Electrocorticography And Cortical Stimulation: A Preliminary Experience.

Type II focal cortical dysplasia is the most common malformation of cortical development associated with drug resistant epilepsy and susceptible to surgical resection. Although advanced imaging modali...

Bone Area Histomorphometry.

Quantifying the amount of cortical bone loss is one variable used in histological methods of adult age estimation. Measurements of cortical area tend to be subjective and additional information regard...

Clinical Trials [416 Associated Clinical Trials listed on BioPortfolio]

Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation

Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbala...

Age Influence on Cortical Bone Measured by Ultrasound

The study of this study is to evaluate the age influence on cortical bone strength properties by two methods:HR-pQCT (HighResolution-peripheral quantitativeComputedTomography) and ultrasou...

The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia

The primary objective of this study is to determine if NAC, added to existing antipsychotic treatment, is superior to placebo for cortical erosion in patients with early stage psychosis. T...

Pathophysiology of Neuronal Oscillations Within Subthalamo-cortical Loops in Parkinson's Disease

Neuronal activity in circuits between the basal ganglia (BG) and motor cortical areas is abnormally synchronised and rhythmic. The oscillatory activity prevails at 8-30 Hz in untreated Par...

Cortical Plasticity Assessment in Athletes With Multiple Concussions

The purpose of this research is to determine whether athletes with concussion have changes in cortical excitability. Single and paired transcranial magnetic stimulation (TMS) can be used ...

Companies [4 Associated Companies listed on BioPortfolio]

Cortical Pty Ltd

Inflammatory diseases can be successfully targeted with anti-cytokine therapies. Small molecule cytokine antagonists have never previously been developed, but may provide a valuable combination of eff...


Orthovita is a unique spine/orthopaedic surgical biomaterials company offering advanced bone regeneration and soft tissue healing technologies. Our experience lies in developing and distributing novel...

iPierian, Inc.

iPierian is a pioneering biopharmaceutical company focusing on harnessing the power of induced pluripotent stem cells (iPSCs) to discover novel therapies that are effective in add...

Orthovita, Inc.

Orthovita, Inc. is a specialty spine and orthopedic company with a portfolio of orthobiologic and biosurgery products. Our products are based on novel and unique proprietary bioma...

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Relevant Topics

Cytokine Tumour Necrosis Factor (TNF)
TNF is a compound that is classified as a cytokine which plays a central role in the cellular mechanisms of apoptosis or cell death. However, there are a number of different kinds of TNF, just under twenty, but the family of molecules have very similar a...

Cytokines include chemokines, lymphokines, and monokines. Cells of the immune system communicate with one another by releasing and responding to chemical messengers called cytokines. These proteins are secreted by immune cells and act on other cells to...

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