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Biological Mimetics, Inc., Company Profile

01:41 EST 18th November 2017 | BioPortfolio

Biological Mimetics, Inc. (“BMI”) was formed to commercialize innovative pharmaceutical products that will improve the quality of life and overall state of public health by combating resistant and emerging diseases in human and veterinary medicine.
Our mission philosophy is to remain a creative and innovative biotechnology firm dedicated to improving the quality of life and overall state of public health through the application of novel technologies for the development and commercialization of human and veterinary biologics to address a long list of hitherto intractable disease targets involving viruses, bacteria, parasites, and cancer.

Based on the Company’s elucidation of a common vaccine evading mechanism of antigenic variation known as “Deceptive Imprinting” used by microbial pathogens and cancer cells, the company has developed a proprietary core technology termed “Immune Dampening and Refocusing”, which uses immune dampening and refocusing to circumvent such evasion mechanisms to: (1) generate vaccines against pathogens for which no effective vaccine exists and (2) improve on the strain or serotype restricted protection of previously tried and currently licensed and used human and veterinary vaccines. In addition, the technology is able to alter the natural antigenicity and immunogenicity of targeted protein antigens to induce and select for unique monoclonal antibodies that can be used for therapeutic, diagnostic, and research purposes. Therapeutic proteins and biologics can also be immune dampened to improve on their biological half-life and safety profiles.

Location

124 Byte Drive,
Frederick
Maryland
21702
United States of America

Contact

Phone: (301) 620-7565
Fax: (301) 620-1827
Email: info@bmi-md.com


News Articles [284 Associated News Articles listed on BioPortfolio]

Hyperosmotic stress enhances cytotoxicity of SMAC mimetics

BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells

Physicochemical and biological characterization study of copy biological tocilizumab

Researchers in China have developed a copy biological of F. Hoffmann-La Roche’s  (Roche) arthritis treatment Actemra (tocilizumab). A recent study compares it to the originator, finding it to b...

Regulatory pathways for approval of biological products in Brazil

Up until 2002, Brazil had no specific guidance for biological products. In 2002 guidelines for biological products were published (RDC 80/2002), which had to be followed by both originator biologicals...

Combination approach improves power of new cancer therapy

An international research team has found a way to improve the anti-cancer effect of a new medicine class called 'Smac mimetics'.

Men are affected by the biological clock as well, researchers find – The Guardian

The GuardianMen are affected by the biological clock as well, researchers findThe GuardianAn ultrasound of a twenty-week old foetus. Scientists have found that a couple's chance of having a baby falls...

Salk Institute for Biological Studies Scientists Solve Longstanding Biological Mystery Of DNA Organization

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Long-term sustained effect of biological psoriasis treatment

Biological treatment of psoriasis shows a good efficacy in clinical trials. Since most analyses have focused on short-term outcomes of single biological agents, little has been known about long-term o...

PubMed Articles [619 Associated PubMed Articles listed on BioPortfolio]

Beyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis.

The emergence of novel binding proteins or antibody mimetics capable of binding to ligand analytes in a manner analogous to that of the antigen-antibody interaction has spurred increased interest in t...

Thrombopoietin mimetics for patients with myelodysplastic syndromes.

Myelodysplastic syndrome (MDS) is one of the most frequent haematologic malignancies of the elderly population and characterised by progenitor cell dysplasia with ineffective haematopoiesis and a high...

Conformation-based design and synthesis of apratoxin A mimetics modified at the α,β-unsaturated thiazoline moiety.

We have demonstrated design, synthesis, and biological evaluation of apratoxin A mimetics. In the first generation, the moCys moiety was replaced with seven simple amino acids as their 3D structures c...

Protein Epitope Mimetics: From New Antibiotics to Supramolecular Synthetic Vaccines.

Protein epitope mimetics provide powerful tools to study biomolecular recognition in many areas of chemical biology. They may also provide access to new biologically active molecules and potentially t...

Synthesis of cyclic peptide mimetics via the successive ring expansion of lactams.

A successive ring expansion protocol is reported that enables the controlled insertion of natural and non-natural amino acid fragments into lactams. Amino acids can be installed into macrocycles via a...

Clinical Trials [1291 Associated Clinical Trials listed on BioPortfolio]

Biological Therapy in Treating Patients With Myelodysplastic Syndrome

RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining different types of biological therapies may kill more cancer...

Safety and Efficacy of Exenatide Injection in Subjects With Type 2 Diabetes Mellitus

Exenatide is the first in a new class of drugs for the treatment of type 2 diabetes mellitus called incretin mimetics. Exenatide resembles a gut hormone, which increases the insulin secret...

Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer

RATIONALE: Learning about the effects of chemotherapy and biological therapy on nerve function may help doctors plan treatment and help patients live more comfortably. PURPOSE: This clini...

Biological Therapy in Treating Women With Stage IV Breast Cancer

RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining different types of biological therapies may kill more tumor ...

Biological Therapy in Treating Patients With Metastatic Cancer

RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. PURPOSE: Phase I trial to study the effectiveness of biological thera...

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