Biological Mimetics, Inc., Company Profile

05:49 EST 17th December 2018 | BioPortfolio

Biological Mimetics, Inc. (“BMI”) was formed to commercialize innovative pharmaceutical products that will improve the quality of life and overall state of public health by combating resistant and emerging diseases in human and veterinary medicine.
Our mission philosophy is to remain a creative and innovative biotechnology firm dedicated to improving the quality of life and overall state of public health through the application of novel technologies for the development and commercialization of human and veterinary biologics to address a long list of hitherto intractable disease targets involving viruses, bacteria, parasites, and cancer.

Based on the Company’s elucidation of a common vaccine evading mechanism of antigenic variation known as “Deceptive Imprinting” used by microbial pathogens and cancer cells, the company has developed a proprietary core technology termed “Immune Dampening and Refocusing”, which uses immune dampening and refocusing to circumvent such evasion mechanisms to: (1) generate vaccines against pathogens for which no effective vaccine exists and (2) improve on the strain or serotype restricted protection of previously tried and currently licensed and used human and veterinary vaccines. In addition, the technology is able to alter the natural antigenicity and immunogenicity of targeted protein antigens to induce and select for unique monoclonal antibodies that can be used for therapeutic, diagnostic, and research purposes. Therapeutic proteins and biologics can also be immune dampened to improve on their biological half-life and safety profiles.


124 Byte Drive,
United States of America


Phone: (301) 620-7565
Fax: (301) 620-1827

News Articles [263 Associated News Articles listed on BioPortfolio]

HDL Mimetics Do Not Enhance Coronary Artery Plaque Regression

Two HDL mimetics containing apolipoprotein A-I (apoA-I) do not enhance regression of coronary-artery plaque in patients with acute coronary syndrome (ACS), according to results from two randomized cli...

Reducing suboptimal prescribing of glucagon-like peptide mimetics in type 2 diabetes

In 2016, spend on diabetes prescribing — and glucagon-like peptide 1 (GLP-1) mimetics, in particular — at NHS Hastings and Rother Clinical Commissioning Group (CCG) and NHS Eastbourne, Hailsham a...

Combining bh3-Mimetics to target both bcl-2 and mcl1 has potent activity in pre-clinical models of acute myeloid leukemia

Introducing Renishaw’s New RA816 Biological Analyser

The new Renishaw RA816 Biological Analyser is a compact benchtop Raman imaging system, designed for biological and clinical research. This easy-to-use instrument enables the rapid collection of detail...

Mid-infrared biosensor distinguishes multiple analytes in heterogeneous biological samples

Detecting biomolecules, such as lipids, proteins, and nucleic acids and their interactions in heterogeneous biological samples is crucial for understanding a multitude of biological mechanisms in heal...

Exposure to violence early in life associated with faster biological aging

A study in Biological Psychiatry has shown that exposure to violence early in life—such as physical, emotional, or sexual abuse—is associated with faster biological aging, including pubertal devel...

A step towards biological warfare with insects?

(Max-Planck-Gesellschaft) A project by a research agency of the US Department of Defense could easily be misused for developing biological weapons.

Children who experience violence early in life develop faster

(Elsevier) A study in Biological Psychiatry has shown that exposure to violence early in life -- such as physical, emotional, or sexual abuse -- is associated with faster biological aging, including p...

PubMed Articles [559 Associated PubMed Articles listed on BioPortfolio]

Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations.

Induction of apoptosis by selective BH3-mimetics is currently investigated as a novel strategy for cancer treatment. Here, we report that selective BH3-mimetics induce apoptosis in a variety of hemato...

Identification of Smac mimetics as novel substrates for p-glycoprotein.

Multidrug resistance (MDR) in cancer patients undergoing chemotherapy is preventing effective treatment of multiple cancer types including pediatric tumors. Resistance to chemotherapeutic drugs in can...

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

Nuclear factor κB (NF-κB) is a transcription factor important for regulating innate and adaptive immunity, cellular proliferation, apoptosis, and senescence. Dysregulation of NF-κB and its upstream...

Photoswitchable glycolipid mimetics: Synthesis and photochromic properties of glycoazobenzene amphiphiles.

Glycolipids as constituents of cell membranes play an important role in cell membrane functioning. To enable the structural modification of membranes on demand, we wish to embed photosensitive glycoli...

Novel alternatives to extracellular vesicle-based immunotherapy - exosome mimetics derived from natural killer cells.

Exosomes are endogenous nanocarriers that can deliver biological information between cells. They are secreted by all cell types, including immune cells such as natural killer (NK) cells. However, mamm...

Clinical Trials [1617 Associated Clinical Trials listed on BioPortfolio]

B Cell Differentiation in MS

Interventional study with minimal risks and constraints, prospective, monocentric.

Safety and Efficacy of Exenatide Injection in Subjects With Type 2 Diabetes Mellitus

Exenatide is the first in a new class of drugs for the treatment of type 2 diabetes mellitus called incretin mimetics. Exenatide resembles a gut hormone, which increases the insulin secret...

Biological Therapy in Treating Patients With Myelodysplastic Syndrome

RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining different types of biological therapies may kill more cancer...

Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer

RATIONALE: Learning about the effects of chemotherapy and biological therapy on nerve function may help doctors plan treatment and help patients live more comfortably. PURPOSE: This clini...

Development of Clinical and Biological Database

The BCB is a tool: - for research in analytical and public health epidemiology, biological research and for the development of data useful for clinical research and therapeutic tr...

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