Cell Signaling Technology, Inc. Company Profile

20:20 EDT 17th June 2018 | BioPortfolio

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned from gene expression profiling, and of the need to examine protein expression and activity. Activation-state-specific antibodies have proven to be a convenient and reliable set of tools in the new post-genomic "research toolbox". Cell Signaling Technology, Inc. (CST) is committed to developing innovative new research tools such as these to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.


3 Trask Lane
United States of America


Phone: 978-867-2300
Fax: 978-867-2488

News Articles [1816 Associated News Articles listed on BioPortfolio]

Uncovering a hidden protein 'tail' that puts the brakes on cell signaling

(Georgia Institute of Technology) Using an informatics tool that identifies "hotspots" of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechan...

Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells

Expression of the B-cell antigen receptor (BCR) is essential not only for the development but also for the maintenance of mature B cells. Similarly, many B-cell lymphomas, including Burkitt lymphoma (...

Graphene Could Strengthen Nerve Signaling in the Brain

ArticleGraphene could hold the key to increasing the strength of nerve cell signaling and enabling nerve cell membranes to pull in more cholesterol.

CiteAb Names Cell Signaling Technology Antibody Company of the Year

“Antibody Company of the Year” and “Antibody Company Succeeding in Cancer Biology" DANVERS, Mass. (PRWEB) February 15, 2018 Cell Signaling Technology. Inc. (CST), a leading provider of ant...

T cell antigen receptors act alone: Longstanding immunological mystery solved

(Vienna University of Technology) With a standard electron microscope, only dead T cells can be studied. Therefore, it is very hard to figure out the inner workings of the cell. New microscopy techniq...

Cell Signaling Technology Expands in China

Cell Signaling Technology (CST), a leading provider of antibodies, kits, and services, has opened a new office in Shanghai, China to support the rapidly expanding China life science market and the gro...

Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival

Non-cell-autonomous function of DR6 in Schwann cell proliferation

Death receptor 6 (DR6) is an orphan member of the TNF receptor superfamily and controls cell death and differentiation in a cell-autonomous manner in different cell types. Here, we report an additiona...

PubMed Articles [6514 Associated PubMed Articles listed on BioPortfolio]

Nuclear inositide signaling and cell cycle.

Phosphatidylinositols (PIs) are responsible for several signaling pathways related to many cellular functions, such as cell cycle regulation at different check-points, cell proliferation, cell differe...

Probing Cilia-Associated Signaling Proteomes in Animal Evolution.

Cilia have evolved to function as essential sensory organelles in animals. To understand why cilia are intimately associated with cell signaling, Sigg et al. (2017) develop and apply a comparative pr...

Wnt signaling in development and tissue homeostasis.

The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication system that is important for stem cell renewal, cell proliferation and cell differentiation both during embr...

The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy.

The Wnt pathway is at the heart of organoid technology, which is set to revolutionize the cancer field. We can now predetermine a patient's response to any given anticancer therapy by exposing tumor o...

MiR-155 regulates lymphoma cell proliferation and apoptosis through targeting SOCS3/JAK-STAT3 signaling pathway.

Janus kinase (JAK)- signal transducer and activator of transcription (STAT) signaling pathway participates in regulating cell proliferation, differentiation, and apoptosis, and related to lymphoma. Su...

Clinical Trials [7454 Associated Clinical Trials listed on BioPortfolio]

Occupational Exposure to Pesticides in the Prognosis of Lymphomas

The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor ...

Osteoclast Inhibition and Bone Formation

This protocol addresses: 1) How gene expression changes in bone cells are affected by aging? 2) Is aging associated with decreased signaling between bone cells? 3) How does treatment with ...

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

The investigators are examining the activation of insulin signaling factors in skeletal muscles of human diabetics. The investigators are characterizing the defects in signaling, and are e...

Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients

The purpose of this study is to demonstrate that orally administered itraconazole, a commonly used antifungal medication, can inhibit Hedgehog pathway signaling in patients with esophageal...

Panitumumab (Vectibix®) in Cutaneous Squamous Cell Carcinoma (SCC)

Squamous Cell Carcinoma (SCC) is one of the most common malignancies in caucasian population. The effect of the immune system on the development of skin tumors has been demonstrated in tra...

Companies [1588 Associated Companies listed on BioPortfolio]

Complexa, Inc.

Complexa, Inc. is a platform biopharmaceutical company researching and developing endogenous human cell signaling technologies targeting an array of prevalent inflammatory and met...

Cell Signaling Technology, Inc.

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned f...

Echelon Biosciences Incorporated

Echelon Biosciences was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, and was incorporated under the laws of the state of Utah as Echelon Research La...

Pulse Biosciences, Inc.

Pulse Biosciences is a medical technology company developing a therapeutic tissue treatment platform based on Nano-Pulse Stimulation, a proprietary cell signaling technology. Publ...

Arbor Vita Corporation.

Arbor Vita is a biopharmaceutical company focused on the discovery, development and commercialization of novel drugs and diagnostics addressing disease through a new family of targets, PDZ proteins. P...

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