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Cell Signaling Technology, Inc. Company Profile

13:07 EDT 24th September 2018 | BioPortfolio

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned from gene expression profiling, and of the need to examine protein expression and activity. Activation-state-specific antibodies have proven to be a convenient and reliable set of tools in the new post-genomic "research toolbox". Cell Signaling Technology, Inc. (CST) is committed to developing innovative new research tools such as these to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

Location

3 Trask Lane
Danvers
Massachusetts
01923
United States of America

Contact

Phone: 978-867-2300
Fax: 978-867-2488
Email: info@cellsignal.com


News Articles [2030 Associated News Articles listed on BioPortfolio]

Uncovering a hidden protein 'tail' that puts the brakes on cell signaling

(Georgia Institute of Technology) Using an informatics tool that identifies "hotspots" of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechan...

Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells

Expression of the B-cell antigen receptor (BCR) is essential not only for the development but also for the maintenance of mature B cells. Similarly, many B-cell lymphomas, including Burkitt lymphoma (...

New chemo-optogenetic method enables multi-directional activity control of cellular processes

Cells need for reactions on environmental changes and a balanced system of signaling cascades within the cell. Proteins outside of the cell, on the cellular surface, inside the cellular membrane, and ...

T cell antigen receptors act alone: Longstanding immunological mystery solved

(Vienna University of Technology) With a standard electron microscope, only dead T cells can be studied. Therefore, it is very hard to figure out the inner workings of the cell. New microscopy techniq...

Human Cell Line for Studies on Signaling and Endocrine Cancer

The first known immortalized cell line with a naturally-occurring inactivating mutation in PRKAR1A, the regulatory subunit type 1A (R1alpha) of protein kinase A (PKA), which is associated with tumor f...

YAP-TEAD signaling promotes basal cell carcinoma development via a c-JUN/AP1 axis

The mammalian Hippo signaling pathway, through its effectors YAP and TAZ, coerces epithelial progenitor cell expansion for appropriate tissue development or regeneration upon damage. Its ability to dr...

Cell Signaling Technology Expands in China

Cell Signaling Technology (CST), a leading provider of antibodies, kits, and services, has opened a new office in Shanghai, China to support the rapidly expanding China life science market and the gro...

Muddied by Mutations, or Drugs, Cell Signaling Can Herald Cancer

The quality of a cell signal, not just its strength, can determine whether a cell will follow a path toward cancer. This finding, which emerged from optogenetic interrogations of both healthy cells an...

PubMed Articles [6444 Associated PubMed Articles listed on BioPortfolio]

B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells.

Type 1 interferon (T1IFN) signaling promotes inflammation and lupus pathology, but its role in autoreactive B cell development in the antibody-forming cell (AFC) and germinal center (GC) pathways is u...

The Domino Effect in EGFR-ERK Signaling.

A gradient of EGFR-ERK signaling has been classically implicated in various developmental processes. In this issue of Developmental Cell, Ogura et al. (2018) show that in the Drosophila tracheal plac...

Wnt signaling in development and tissue homeostasis.

The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication system that is important for stem cell renewal, cell proliferation and cell differentiation both during embr...

Comparative Analysis of Regulatory Role of Notch Signaling Pathway in 8 Types Liver Cell During Liver Regeneration.

Notch signaling is closely related to cell proliferation, cell apoptosis, cell fate decisions, DNA damage repair, and so on. However, the exactly regulatory mechanism of Notch signaling pathway in liv...

Binding of EphrinA5 to RET receptor tyrosine kinase: An in vitro study.

Eph/Ephrin signaling pathways are crucial in regulating a large variety of physiological processes during development, such as cell morphology, proliferation, migration and axonal guidance. EphrinA (e...

Clinical Trials [7912 Associated Clinical Trials listed on BioPortfolio]

Occupational Exposure to Pesticides in the Prognosis of Lymphomas

The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor ...

Osteoclast Inhibition and Bone Formation

This protocol addresses: 1) How gene expression changes in bone cells are affected by aging? 2) Is aging associated with decreased signaling between bone cells? 3) How does treatment with ...

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

The investigators are examining the activation of insulin signaling factors in skeletal muscles of human diabetics. The investigators are characterizing the defects in signaling, and are e...

Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients

The purpose of this study is to demonstrate that orally administered itraconazole, a commonly used antifungal medication, can inhibit Hedgehog pathway signaling in patients with esophageal...

Panitumumab (Vectibix®) in Cutaneous Squamous Cell Carcinoma (SCC)

Squamous Cell Carcinoma (SCC) is one of the most common malignancies in caucasian population. The effect of the immune system on the development of skin tumors has been demonstrated in tra...

Companies [1599 Associated Companies listed on BioPortfolio]

Complexa, Inc.

Complexa, Inc. is a platform biopharmaceutical company researching and developing endogenous human cell signaling technologies targeting an array of prevalent inflammatory and met...

Cell Signaling Technology, Inc.

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned f...

Echelon Biosciences Incorporated

Echelon Biosciences was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, and was incorporated under the laws of the state of Utah as Echelon Research La...

Pulse Biosciences, Inc.

Pulse Biosciences is a medical technology company developing a therapeutic tissue treatment platform based on Nano-Pulse Stimulation, a proprietary cell signaling technology. Publ...

Arbor Vita Corporation.

Arbor Vita is a biopharmaceutical company focused on the discovery, development and commercialization of novel drugs and diagnostics addressing disease through a new family of targets, PDZ proteins. P...

More Information about "Cell Signaling Technology, Inc." on BioPortfolio

We have published hundreds of Cell Signaling Technology, Inc. news stories on BioPortfolio along with dozens of Cell Signaling Technology, Inc. Clinical Trials and PubMed Articles about Cell Signaling Technology, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Cell Signaling Technology, Inc. Companies in our database. You can also find out about relevant Cell Signaling Technology, Inc. Drugs and Medications on this site too.

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