Cell Signaling Technology, Inc. Company Profile

16:04 EDT 24th March 2018 | BioPortfolio

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned from gene expression profiling, and of the need to examine protein expression and activity. Activation-state-specific antibodies have proven to be a convenient and reliable set of tools in the new post-genomic "research toolbox". Cell Signaling Technology, Inc. (CST) is committed to developing innovative new research tools such as these to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.


3 Trask Lane
United States of America


Phone: 978-867-2300
Fax: 978-867-2488

News Articles [1681 Associated News Articles listed on BioPortfolio]

Graphene Could Strengthen Nerve Signaling in the Brain

ArticleGraphene could hold the key to increasing the strength of nerve cell signaling and enabling nerve cell membranes to pull in more cholesterol.

CiteAb Names Cell Signaling Technology Antibody Company of the Year

“Antibody Company of the Year” and “Antibody Company Succeeding in Cancer Biology" DANVERS, Mass. (PRWEB) February 15, 2018 Cell Signaling Technology. Inc. (CST), a leading provider of ant...

Human Cell Line for Studies on Signaling and Endocrine Cancer

The National Institute of Child and Human Development seeks interested parties to further co-developa cell line with mutations in PRKAR1A, associated with tumor formation, for use a diagnostic or rese...

Compound Found in Red Wine Boosts Immune Cell Function

A low doses, resveratrol enhanced human T cell activity in vitro, while at high doses it interfered with cell signaling.

Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation

Study links mutations in notch gene to role in B cell cancers

In B cell tumors, mutated overactive versions of the Notch protein directly drive the expression of the Myc gene and many other genes that participate in B cell signaling pathways, researchers have fo...

Corvus Pharmaceuticals Announces Presentation of New Data from Preclinical Study of Novel T-Cell Signaling Pathway Inhibitor at 10th Annual T-Cell Lymphoma Forum

BURLINGAME, Calif., Feb. 01, 2018 (GLOBE NEWSWIRE) -- Corvus Pharmaceuticals, Inc. (NASDAQ:CRVS), a clinical-stage biopharmaceutical company focused on the development and commercialization of pr...

Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion

The Fos-related antigen 1 (FRA-1) transcription factor promotes tumor cell growth, invasion and metastasis. Phosphorylation of FRA-1 increases protein stability and function. We identify a novel signa...

PubMed Articles [6622 Associated PubMed Articles listed on BioPortfolio]

Signaling network-based functional cell design.

Cellular signaling networks act as the central processor to deal with environmental signals and regulate cell function, and determine cell fate. Using synthetic biology approach to engineer cell signa...

Nuclear inositide signaling and cell cycle.

Phosphatidylinositols (PIs) are responsible for several signaling pathways related to many cellular functions, such as cell cycle regulation at different check-points, cell proliferation, cell differe...

Probing Cilia-Associated Signaling Proteomes in Animal Evolution.

Cilia have evolved to function as essential sensory organelles in animals. To understand why cilia are intimately associated with cell signaling, Sigg et al. (2017) develop and apply a comparative pr...

Stem Cell Smart Technology, where are we now and how far we have to go?

Approximately eight million people in the United States have peripheral arterial disease, which increases exponentially with age. There have been a plethora of available treatments including surgery, ...

The Central Role of Wnt Signaling and Organoid Technology in Personalizing Anticancer Therapy.

The Wnt pathway is at the heart of organoid technology, which is set to revolutionize the cancer field. We can now predetermine a patient's response to any given anticancer therapy by exposing tumor o...

Clinical Trials [7184 Associated Clinical Trials listed on BioPortfolio]

Occupational Exposure to Pesticides in the Prognosis of Lymphomas

The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor ...

Osteoclast Inhibition and Bone Formation

This protocol addresses: 1) How gene expression changes in bone cells are affected by aging? 2) Is aging associated with decreased signaling between bone cells? 3) How does treatment with ...

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

The investigators are examining the activation of insulin signaling factors in skeletal muscles of human diabetics. The investigators are characterizing the defects in signaling, and are e...

Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients

The purpose of this study is to demonstrate that orally administered itraconazole, a commonly used antifungal medication, can inhibit Hedgehog pathway signaling in patients with esophageal...

Panitumumab (Vectibix®) in Cutaneous Squamous Cell Carcinoma (SCC)

Squamous Cell Carcinoma (SCC) is one of the most common malignancies in caucasian population. The effect of the immune system on the development of skin tumors has been demonstrated in tra...

Companies [1573 Associated Companies listed on BioPortfolio]

Complexa, Inc.

Complexa, Inc. is a platform biopharmaceutical company researching and developing endogenous human cell signaling technologies targeting an array of prevalent inflammatory and met...

Cell Signaling Technology, Inc.

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned f...

Echelon Biosciences Incorporated

Echelon Biosciences was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, and was incorporated under the laws of the state of Utah as Echelon Research La...

Pulse Biosciences, Inc.

Pulse Biosciences is a medical technology company developing a therapeutic tissue treatment platform based on Nano-Pulse Stimulation, a proprietary cell signaling technology. Publ...

Arbor Vita Corporation.

Arbor Vita is a biopharmaceutical company focused on the discovery, development and commercialization of novel drugs and diagnostics addressing disease through a new family of targets, PDZ proteins. P...

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Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...

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