Cell Signaling Technology, Inc. Company Profile

01:07 EST 25th November 2017 | BioPortfolio

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned from gene expression profiling, and of the need to examine protein expression and activity. Activation-state-specific antibodies have proven to be a convenient and reliable set of tools in the new post-genomic "research toolbox". Cell Signaling Technology, Inc. (CST) is committed to developing innovative new research tools such as these to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.


3 Trask Lane
United States of America


Phone: 978-867-2300
Fax: 978-867-2488

News Articles [1766 Associated News Articles listed on BioPortfolio]

Cell Signaling Technology Announces European Operations Changes

Cell Signaling Technology (CST), a leading provider of antibodies, kits, and services, has announced changes in part of its European operations. Danvers, MA (PRWEB) September 05, 2017 Cell Signaling ...

Sending the right signals

(University of Pittsburgh) Warren Ruder, assistant professor in the Department of Bioengineering at the University of Pittsburgh Swanson School of Engineering, is developing microparticles that carry ...

Manipulating 'signaling' molecules to control cell migration

A mechanism in amoebae that rapidly changes the way cells migrate by resetting their sensitivity to the naturally occurring internal signaling events that drive such movement has now been discovered b...

Compound Found in Red Wine Boosts Immune Cell Function

A low doses, resveratrol enhanced human T cell activity in vitro, while at high doses it interfered with cell signaling.

Integrin {alpha}v{beta}3 enhances the suppressive effect of interferon-{gamma} on hematopoietic stem cells

Hematopoietic homeostasis depends on the maintenance of hematopoietic stem cells (HSCs), which are regulated within a specialized bone marrow (BM) niche. When HSC sense external stimuli, their adhesio...

Nonimmune cells equipped with T-cell-receptor-like signaling for cancer cell ablation

Scientists Manipulate 'Signaling' Molecules to Control Cell Migration

NewsExperiments in single-celled organisms have implications for blocking cancer metastasis and other disease-related cell movements.

Acid sphingomyelinase mediates human CD4+ T-cell signaling: potential roles in T-cell responses and diseases

PubMed Articles [6626 Associated PubMed Articles listed on BioPortfolio]

Signaling network-based functional cell design.

Cellular signaling networks act as the central processor to deal with environmental signals and regulate cell function, and determine cell fate. Using synthetic biology approach to engineer cell signa...

Nuclear inositide signaling and cell cycle.

Phosphatidylinositols (PIs) are responsible for several signaling pathways related to many cellular functions, such as cell cycle regulation at different check-points, cell proliferation, cell differe...

Application of single-cell technology in cancer research.

In this review, we have outlined the application of single-cell technology in cancer research. Single-cell technology has made encouraging progress in recent years and now provides the means to detect...

Stem Cell Smart Technology, where are we now and how far we have to go?

Approximately eight million people in the United States have peripheral arterial disease, which increases exponentially with age. There have been a plethora of available treatments including surgery, ...

Notch inhibitors and their role in the treatment of triple negative breast cancer: promises and failures.

Notch signaling is a highly evolutionarily conserved cell-to-cell communication system that is involved in a number of pivotal cellular processes, such as development, stem cell maintenance, cell fate...

Clinical Trials [6707 Associated Clinical Trials listed on BioPortfolio]

Occupational Exposure to Pesticides in the Prognosis of Lymphomas

The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor ...

Osteoclast Inhibition and Bone Formation

This protocol addresses: 1) How gene expression changes in bone cells are affected by aging? 2) Is aging associated with decreased signaling between bone cells? 3) How does treatment with ...

Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

The investigators are examining the activation of insulin signaling factors in skeletal muscles of human diabetics. The investigators are characterizing the defects in signaling, and are e...

Itraconazole as a Targeted Therapy for Inhibiting Hedgehog Pathway Signaling in Esophageal Cancer Patients

The purpose of this study is to demonstrate that orally administered itraconazole, a commonly used antifungal medication, can inhibit Hedgehog pathway signaling in patients with esophageal...

Panitumumab (Vectibix®) in Cutaneous Squamous Cell Carcinoma (SCC)

Squamous Cell Carcinoma (SCC) is one of the most common malignancies in caucasian population. The effect of the immune system on the development of skin tumors has been demonstrated in tra...

Companies [1559 Associated Companies listed on BioPortfolio]

Complexa, Inc.

Complexa, Inc. is a platform biopharmaceutical company researching and developing endogenous human cell signaling technologies targeting an array of prevalent inflammatory and met...

Cell Signaling Technology, Inc.

The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned f...

Echelon Biosciences Incorporated

Echelon Biosciences was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, and was incorporated under the laws of the state of Utah as Echelon Research La...

Pulse Biosciences, Inc.

Pulse Biosciences is a medical technology company developing a therapeutic tissue treatment platform based on Nano-Pulse Stimulation, a proprietary cell signaling technology. Publ...

Arbor Vita Corporation.

Arbor Vita is a biopharmaceutical company focused on the discovery, development and commercialization of novel drugs and diagnostics addressing disease through a new family of targets, PDZ proteins. P...

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