Donohue Brown Mathewson & Smyth LLC Company Profile

08:55 EST 20th November 2017 | BioPortfolio

Donohue Brown Mathewson & Smyth LLC is one of Chicago’s pre-eminent trial practice boutiques. Founded in 1995 by partners from the worldwide law firm of Baker & McKenzie, the firm successfully tries difficult, high exposure cases in the country’s most challenging jurisdictions. The firm is known as one of the “go to” firms in Chicago for particularly difficult or high stakes cases and, since its founding, no firm in Chicago has tried as many complex cases as successfully as DBM&S LLC. Two partners have been ranked by Chicago Lawyer magazine as among the top 20 tort defense lawyers in Chicago and four partners have been elected as Fellows of The American College of Trial Lawyers.


140 South Dearborn, Suite 800
United States of America


Phone: (312) 422-0900
Fax: (312) 422-0909

News Articles [238 Associated News Articles listed on BioPortfolio]

Brown to study music program for nursing home residents with dementia

(Brown University) Researchers at Brown's Center for Long-Term Care Quality and Innovation landed a $3.7 million grant to conduct a pragmatic cluster randomized trial of the MUSIC & MEMORY program at ...

Enhancing brown fat with NFIA

Brown adipose tissue is a key metabolic organ that oxidizes fatty acids and glucose to generate heat. Through epigenomic analyses of multiple adipose depots, the transcription factor nuclear factor I-...

US renews Brown University addiction center's funding with emphasis on opioids

(Brown University) With a new $3.8 million grant, the federal government has renewed funding for Brown University's New England Addiction Technology Transfer Center for the next five years.

New equipment maps brain activity and blood flow in state-of-the-art neuroscience lab

(University of Alberta) The optical brain-imaging tool, called the Imagent, comes to the University of Alberta as the result of new funding for neuroscientist Kyle Mathewson, from the John R. Evans Le...

NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program

Hiraike et al. identify nuclear factor I-A (NFIA) as a transcriptional regulator of brown fat. NFIA activates cell-type-specific enhancers prior to differentiation and facilitates PPARγ binding to ...

Dong et al. reply

Replying toN. J. L.Brown, C. J.Albers & S. J.RitchieNature546, (2017)In the accompanying Comment, Brown et al. question our analyses and hence the evidence for a ...

New Skin Patch Helps Reduce 'Love Handles' In Mice

The patch delivered browning agents that aim to convert white fat to brown fat. What is brown fat?

Political polarization? Don't blame the web, Brown study says

(Brown University) Despite the popular narrative that the web is to blame for rising political polarization, a study by a Brown University economist has found that recent growth in polarization is gre...

PubMed Articles [235 Associated PubMed Articles listed on BioPortfolio]

Loss of the tumor suppressor gene AIP mediates the browning of human brown fat tumors.

Human brown fat tumors (hibernomas) display concomitant loss of the tumor suppressor genes MEN1 and AIP. In the present study, we hypothesized that the brown fat phenotype is attributed to these mutat...

NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.

Brown fat dissipates energy as heat and protects against obesity. Here, we identified nuclear factor I-A (NFIA) as a transcriptional regulator of brown fat by a genome-wide open chromatin analysis of ...

Out of southern East Asia of the brown rat revealed by large scale genome sequencing.

The geographic origin and migration of the brown rat (Rattus norvegicus) remain subjects of considerable debate. In this study, we sequenced whole genomes of 110 wild brown rats with a diverse world-w...

Brown and brite adipocytes: Same function, but different origin and response.

Inducing brown adipocytes in white adipose tissues is a promising target to combat obesity and its related disorders in human beings. This goal has been especially encouraged by new important discover...

What Ignites UCP1?

We thought we knew how the heat-producing uncoupling protein 1 in brown adipose tissue was activated: by fatty acids released upon lipid droplet breakdown in the brown adipocytes. However, two studies...

Clinical Trials [81 Associated Clinical Trials listed on BioPortfolio]

Cold Induced Activation of Brown Adipose Tissue in Humans

This study investigates cold-induced brown fat activation assessed using PET/MR scans. Subjects will participate in an acute cooling intervention day and a thermoneutral intervention day w...

The Effects of Capsinoids on Brown Adipose Tissue Activation in Obesity

This research study is being done to determine whether taking a dietary supplement called capsinoids, derived from sweet peppers, can activate brown fat that is already present or even gen...

Effect of Fluvastatin on Brown Fat Activity

The purpose of this study is to elucidate the effects of Fluvastatin on brown adipose tissue activity in humans.

HIV Fat Redistribution and the Evaluation of Brown Fat

The specific aims of this study are to determine whether HIV-infected patients with significant fat redistribution and ectopic fat accumulation have increased brown adipose tissue using 18...

Brown Rice Intervention on Metabolic Syndrome (BRIMS)

The specific aim of this study is to determine the effects of substituting brown for white rice on the treatment of metabolic syndrome (MetS).

Companies [62 Associated Companies listed on BioPortfolio]

Donohue Brown Mathewson & Smyth LLC

Donohue Brown Mathewson & Smyth LLC is one of Chicago’s pre-eminent trial practice boutiques. Founded in 1995 by partners from the worldwide law firm of Baker & McKenzie, the firm successfully tries...

Brown & Toland Physicians

Brown & Toland is one of California's largest and most successful physician networks. A leader in providing innovative technological solutions for its physicians, Brown & Toland has earned numerous aw...

Brown Shoe Company, Inc.

Brown Shoe is a $2.2 billion footwear company with global operations. Brown Shoe's Retail division operates Famous Footwear, the more than 1,100-store chain that sells brand name shoes for the family;...


The Sanford-Brown name dates back to 1866 when Rufus C. Crampton, a professor at Illinois College, established a school to meet the growing educational demands of post-Civil War A...

Brown & Toland Medical Group

Brown & Toland Medical Group's 1,500 physicians care for close to 190,000 HMO and approximately 100,000 PPO patients. Brown & Toland receives numerous awards for its medical excellence and preven...

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