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Direct Therapeutics, Inc. Company Profile

16:04 EDT 20th September 2018 | BioPortfolio

Direct Therapeutics, Inc. is a development-stage pharmaceutical company using its patented Solvent-Facilitated Perfusion technology to create new drugs for the localized and regional treatment of solid-tumor cancers. Our products are designed for direct injection to target tissue with minimal invasion of healthy tissue. They contain active ingredients in organic solvent vehicles that facilitate the penetration of the drug throughout tumor tissue and into tumor cells. In contrast to "sustained release" or "controlled release" products, our products rapidly, selectively, and thoroughly saturate tumors with doses of potent chemotherapeutic agents unachievable by other means. We have demonstrated that these products, when directly applied by needle or catheter to solid tumors, perfuse preferentially throughout the tumor, leading to rapid, selective death of cancerous tissue.
We have completed two Phase I/II studies of our lead product, DTI-015 in the United States for the treatment of brain cancer, and will start our first European trial of DTI-015 in Q1 2003. In November 2002 , we received notice from the US FDA that the company had satisfied the necessary requirements to initiate a Phase III product-registration trial of DTI-015 in patients with glioblastoma multiforme, the most common and deadly form of brain cancer. In addition, we are pursuing development of new Solvent-Facilitated Perfusion products, which have shown positive results in pre-clinical studies.

Location

460 Seaport Court, Suite 220
Redwood
California
94063
United States of America

Contact

Email: main@directtherapeutics.com


News Articles [1311 Associated News Articles listed on BioPortfolio]

Recurrence of HCC Following Direct-acting Antiviral Therapy

Might direct-acting antivirals increase risk and aggressiveness of hepatocellular carcinoma recurrence? This review aimed to characterize HCC recurrence patterns after DAA therapy. Alimentary Pharma...

Arch Therapeutics, Inc. $4.5 Million Registered Direct Offering

FRAMINGHAM, Mass., June 29, 2018 (GLOBE NEWSWIRE) -- Arch Therapeutics, Inc. (OTCQB:ARTH) (“Arch” or the “Company”), a developer of innovative materials as hemostatic and wound care device...

VBL Therapeutics Announces Closing of $15.5 Million Registered Direct Offering

TEL AVIV, Israel, June 27, 2018 (GLOBE NEWSWIRE) -- VBL Therapeutics (Nasdaq:VBLT), a clinical-stage biotechnology company focused on the discovery, development and commercialization of first-in-c...

Pain Therapeutics Announces Closing of $11.3 Million Registered Direct Offering

AUSTIN, Texas, Aug. 17, 2018 (GLOBE NEWSWIRE) -- Pain Therapeutics, Inc. (Nasdaq: PTIE), a biopharmaceutical company, today announced the closing of its previously announced registered direct offer...

VBL Therapeutics Announces $15.5 Million Registered Direct Offering Priced At-the-Market

TEL AVIV, Israel, June 26, 2018 (GLOBE NEWSWIRE) -- VBL Therapeutics (Nasdaq:VBLT), a clinical-stage biotechnology company focused on the discovery, development and commercialization of first-in-c...

Pain Therapeutics Announces $11.3 Million Registered Direct Offering Priced At-the-Market

AUSTIN, Texas, Aug. 16, 2018 (GLOBE NEWSWIRE) -- Pain Therapeutics, Inc. (Nasdaq: PTIE), a biopharmaceutical company, today announced that it has entered into definitive agreements with several ins...

Adaptimmune Therapeutics plc Announces Closing of Registered Direct Offering of American Depositary Shares

PHILADELPHIA, Pa. and OXFORD, U.K., Sept. 07, 2018 (GLOBE NEWSWIRE) -- Adaptimmune Therapeutics plc (“Adaptimmune”) (Nasdaq: ADAP), a leader in T-cell therapy to treat cancer, today announced t...

Adaptimmune nets $99.7mm through registered direct offering

Adaptimmune Therapeutics LLC netted $99.7mm through a registered direct offering of 10mm American Depositary Shares (representing 60mm ordinary shares) priced at $10 per ADS. Funds will go towards dev...

PubMed Articles [990 Associated PubMed Articles listed on BioPortfolio]

Role of Direct-Acting Antivirals in Hepatitis C Virus-Positive Castleman Disease.

RNA Therapeutics (Almost) Comes of Age: Targeting, Delivery and Endosomal Escape.

Recent developments in intracellular protein delivery.

Protein therapeutics based on transcription factors, gene editing enzymes, signaling proteins and protein antigens, have the potential to provide cures for a wide number of untreatable diseases, but c...

Myt1l induced direct reprogramming of pericytes into cholinergic neurons.

The cholinergic deficit is thought to underlie progressed cognitive decline in Alzheimer Disease. The lineage reprogramming of somatic cells into cholinergic neurons may provide strategies toward cell...

A Review of Therapeutics in Clinical Development for Respiratory Syncytial Virus and Influenza in Children.

Respiratory syncytial virus (RSV) and influenza are important viral pathogens worldwide. Children, in particular, bear considerable burdens of morbidity and mortality associated with these viruses. Th...

Clinical Trials [1475 Associated Clinical Trials listed on BioPortfolio]

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act...

A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered i...

Direct Anterior Approach Versus Direct Lateral Approach in Total Hip Arthroplasty

The purpose of this study is to compare the direct anterior approach and the direct lateral approach in primary total hip arthroplasty, regarding the postoperative function and pain, compl...

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More Information about "Direct Therapeutics, Inc." on BioPortfolio

We have published hundreds of Direct Therapeutics, Inc. news stories on BioPortfolio along with dozens of Direct Therapeutics, Inc. Clinical Trials and PubMed Articles about Direct Therapeutics, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Direct Therapeutics, Inc. Companies in our database. You can also find out about relevant Direct Therapeutics, Inc. Drugs and Medications on this site too.

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