Dendritic NanoTechnologies Inc Company Profile

09:25 EST 22nd November 2017 | BioPortfolio

Dendritic NanoTechnologies Inc. (DNT) is the world’s leading developer and provider of advanced dendritic polymers. DNT has breakthrough technology that provides the vehicle — the targeting and delivery mechanisms — for a vast array of diagnostics and therapeutics currently in development in the biotechnology and pharmaceutical industries.DNT is a U.S. company incorporated in 2003 and located in Mount Pleasant, Michigan on the campus of Central Michigan University (CMU). DNT is developing and commercializing dendrimers — a type of polymer. These new types of nanostructures (particles so small they allow us to build new structures, literally, atom-by-atom) hold great promise for real-world applications, such as biotechnology and pharmaceuticals. DNT's business strategies are based on a broad technology platform advanced by DNT's founder, Donald A. Tomalia, Ph.D. from his initial discovery of dendrimers in 1979.


2625 Denison Drive
Mount Pleasant
United States of America


Phone: (989) 774-4199
Fax: (989) 774-2322

News Articles [45 Associated News Articles listed on BioPortfolio]

Enhanced IFN-α production is associated with increased TLR7 retention in the lysosomes of palasmacytoid dendritic cells in systemic lupus erythematosus

Interferon-α (IFN-α) is increased and plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Plasmacytoid dendritic cells (pDCs) are the main producer of IFN-α, but thei...

Dendritic cells 'divide and conquer' to elude viral infection while promoting immunity

A research team led by Jackson Laboratory (JAX) Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a lo...

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-sta...

Order in disorder: A key feature of dendritic organization in the brain

(Max Planck Florida Institute for Neuroscience) Fitzpatrick and colleagues find that synaptic inputs in the visual cortex are locally -- but not globally -- organized. This local functional synaptic c...

PAR-1 promotes microtubule breakdown during dendrite pruning in Drosophila

Pruning of unspecific neurites is an important mechanism during neuronal morphogenesis. Drosophila sensory neurons prune their dendrites during metamorphosis. Pruning dendrites are severed in their pr...

Lineage specification of human dendritic cells is marked by IRF8 expression in hematopoietic stem cells and multipotent progenitors

Liu and colleagues show that specification of the dendritic-cell lineage occurs in parallel with specification of the myeloid and lymphoid lineages in or around the hematopoietic-stem-cell stage, star...

Dendritic cells: Managing migration

Fetal dendritic cells give mum a break

Drugs and Medications [9 Associated Drugs and Medications listed on BioPortfolio]

Viroptic [Monarch Pharmaceuticals, Inc]

VIROPTIC Ophthalmic Solution, 1% Sterile(trifluridine ophthalmic solution)

Zirgan [Bausch & Lomb Incorporated]

These highlights do not include all the information needed to use ZIRGAN safely and effectively. See full prescribing information for ZIRGAN.ZIRGAN (ganciclovir ophthalmic gel) 0.15%Initial U.S. Appro...

Trifluridine [Falcon Pharmaceuticals, Ltd.]


Statrol®neomycin and polymyxin bsulfates ophthalmic ointment, usp [ALCON LABORATORIES, INC.]

Statrol®neomycin and polymyxin Bsulfates ophthalmic ointment, USP

Statrol®neomycin and polymyxin bsulfates ophthalmic solution, usp [Alcon]

Statrol®neomycin and polymyxin Bsulfates ophthalmic solution, USP

PubMed Articles [344 Associated PubMed Articles listed on BioPortfolio]

Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation.

We discuss the state of the art and innovative micro- and nanoscale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applic...

Drebrin and Spine Formation.

Dendritic spines are the postsynaptic receptive regions of most excitatory synapses in the central nervous system. Thus, spines are supposed to act as a fundamental unit for information processing of ...

Non-neoplastic histiocytic and dendritic cell disorders in lymph nodes.

Benign and malignant proliferations of histiocytes and dendritic cells may be encountered in lymph nodes. Reactive histiocytic and dendritic cell infiltrates occur in response to diverse stimuli and i...

Antigenic GM3 Lactone Mimetic Molecule Integrated Mannosylated Glycopeptide Nanofibers for the Activation and Maturation of Dendritic Cells.

The ability of dendritic cells to coordinate innate and adaptive immune responses makes them essential targets for vaccination strategies. Presentation of specific antigens by dendritic cells is requi...

Nanoantibiotics: a new paradigm for the treatment of surgical infection.

Infections following orthopedic device implantations often impose a substantial health burden and result in high medical costs. Currently, preventative methods are often employed following an orthoped...

Clinical Trials [297 Associated Clinical Trials listed on BioPortfolio]

Tumor Lysate Pulsed Dendritic Cell Immunotherapy for Patients With Brain Tumors

This research is being determine whether vaccinations with your own immune cells called " dendritic cells " can activate your immune system to fight your brain tumor.

Dendritic Cell Vaccine Study (DC/PC3) for Prostate Cancer

The purpose of this study is to assess the safety and activity of DC/PC3, a dendritic cell vaccine used as immunotherapy for prostate cancer. The vaccine is made with each participants' o...

A Pilot Study of Immunization With HIV-1 Antigen Pulsed Allogenic Dendritic Cells in HIV-Infected Asymptomatic Patients With CD4+ T Cells > 350 Cells/mm3

To define the safety and efficacy of sibling-supplied, HIV antigen-pulsed dendritic cells in increasing the immune response in HIV-infected patients. Dendritic cells are a type of white b...

Alpha-Type 1 Dendritic Cell (DC)-Based Vaccines Loaded With Allogeneic Prostate Cell Lines in Combination With Androgen Ablation in Patients With Prostate Cancer

Dendritic cells or "DCs" are special white blood cells that stimulate the immune system. This study is being done to test the feasibility, safety and efficacy of a specific type of dendrit...

Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme

Adult patients who have surgical resection of newly diagnosed glioblastoma multiforme will be treated with radiotherapy/chemotherapy followed by dendritic cell vaccine. Chemotherapy will ...

Companies [30 Associated Companies listed on BioPortfolio]

Dendritic NanoTechnologies Inc

Dendritic NanoTechnologies Inc. (DNT) is the world’s leading developer and provider of advanced dendritic polymers. DNT has breakthrough technology that provides the vehicle — the targeting and de...

BioTime, Inc. and Asterias Biotherapeutics, Inc.

Asterias Biotherapeutics, Inc. is a leading biotechnology company in the emerging field of regenerative medicine. The company’s proprietary, industry leading platforms are ba...


DCPrime develops off-the-shelf dendritic cell-based vaccines for a broad range of cancer types, based on its unique, proprietary technology platform, DCOne™. DCOne-based dend...

MagForce Nanotechnologies AG

MagForce Nanotechnologies AG is a world-leading company in the area of nanotechnology-based cancer treatment. Its patented Nano-Cancer® therapy enables the targeted destruction...

The Project on Emerging Nanotechnologies

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A diagnostic test is any kind of medical test performed to aid in the diagnosis or detection of disease. For example: to diagnose diseases to measure the progress or recovery from disease to confirm that a person is free from disease Clin...

Antibodies Antisense Assays Biochips Bioinformatics Biological Therapy Biomarkers Biomaterials Bioscience Cell Culture Cloning Cytokine Diagnostics Dna Extraction Dna Sequencing Dna Transform...

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"using living things to create products or to do tasks for humans" About Biotechnology - Biotech Biotechnology is the practice of using plants, animals and micro-organisms such as bacteria, as well as biological processes - such as the ripen...

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