14:51 EST 19th November 2017 | BioPortfolio




News Articles [1259 Associated News Articles listed on BioPortfolio]

Drug Discovery Today: highlighted review. ‘Metabolite-likeness’ as a criterion in the design and selection of pharmaceutical drug libraries

This highlighted review from Drug Discovery Today by Dobson, Patel and Kell outlines how "metabolite-likeness" in an analogous manner to "drug-likeness" and "lead-likeness" can be used to improve the ...

FDA Denies Approval of PTC’s Duchenne Muscular Dystrophy Drug Translarna

SOUTH PLAINFIELD, N.J., Oct. 25, 2017 /PRNewswire/ — PTC Therapeutics, Inc. (NASDAQ: PTCT) today announced that the Office of Drug Evaluation I of the U.S. Food and Drug Administration (FDA) has...

Drug Discovery Today Citation Classic: The growing impact of click chemistry on drug discovery.

Welcome to the first article in Drug Discovery Today Citation Classics. I would say that it is very hard to predict what articles will make citation classic articles, but I suppose that having a Nobel...

FDA Approves IRWD's Gout Drug, It's A Thumbs Up For ALXN In EU, CRME Crushed

Today's Daily Dose brings you news about European approval of Alexion's Soliris for an additional indication; Alkermes' New Drug Application for a major depressive disorder drug; Astellas' MORPHO tria...

Medical News Today: Could an epilepsy drug help to slow Alzheimer's?

A drug used to reduce seizures has been found to normalize brain wave frequencies in patients with Alzheimer's. Could this drug help to slow the disease?

Drug OK'd for Preventing CMV Infection in Bone Marrow Transplant

(MedPage Today) -- Letermovir is first drug for this indication

FDA Grants Orphan Drug Designation to PhaseRx’s Rare Liver Disease Drug

SEATTLE, Sept. 20, 2017 /PRNewswire/ — PhaseRx, Inc. (NASDAQ: PZRX), a biopharmaceutical company developing mRNA treatments for life-threatening inherited liver diseases in children, today annou...

CMS Puts Brakes on Part B Drug Payment Demo

(MedPage Today) -- Demonstration project would have included a flat fee for drug administration

PubMed Articles [2476 Associated PubMed Articles listed on BioPortfolio]

Computational drug repositioning for rare diseases in the era of precision medicine.

There are tremendous unmet needs in drug development for rare diseases. Computational drug repositioning is a promising approach and has been successfully applied to the development of treatments for ...

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

A considerable number of approved drugs show non-equilibrium binding characteristics, emphasizing the potential role of drug residence times for in vivo efficacy. Therefore, a detailed understanding o...

Safety and Efficacy of Antibacterial Prophylaxis After Craniotomy: A Decision Model Analysis.

Antibiotic prophylaxis has revolutionized the safety of neurosurgical procedures in the last century. Today, the clinician's drug of choice prior surgery is often based on the antibiotic's resistance ...

Dendrimer nanohybrid carrier systems: an expanding horizon for targeted drug and gene delivery.

Highly controllable dendritic structural design means dendrimers are a leading carrier in drug delivery applications. Dendrimer- and other nanocarrier-based hybrid systems are an emerging platform in ...

Targeting survivin for therapeutic discovery: past, present, and future promises.

Survivin, the smallest member of the inhibitor of apoptosis protein (IAP) family, is overexpressed in cells of almost all cancers but not in most normal tissues in adults. Survivin expression is requi...

Clinical Trials [2171 Associated Clinical Trials listed on BioPortfolio]

Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) has sponsored a consortium of investigators to conduct a clinical tr...

Joint Status in Subjects With Severe Hemophilia A in Relation to Different Treatment Regimens

The joint status (knees, ankles) of patients suffering from severe Hemophilia A (too little blood clotting factor VIII in blood) is evaluated in a single magnetic resonance imaging session...

Intra-patient Study With Polymer Free Drug Eluting Stent Versus Abluminal Biodegradable Polymer Drug Eluting Stent With Early OCT (Optical Coherence Tomography) Follow up

The objective of the study is to evaluate the process of early re-endothelialization of the Coroflex® ISAR Drug-eluting stent compared with the Ultimaster® Drug-eluting stent

Basel Stent Kosten Effektivitäts Trial Drug Eluting Balloons vs. Drug Eluting Stents in Small Vessel Interventions

The investigators hypothesize that in a real-world population undergoing percutaneous coronary intervention (PCI) for de-novo stenoses in small native vessels with a diameter

Driving Ability of Drug Dependant Patients in Maintenance Therapy

"Mobility" is a contributing factor in today's society. Drug dependence displays not only a medical but also an economic problem: Especially for an intended reintegration of a drug dependa...

Companies [1911 Associated Companies listed on BioPortfolio]



Lil' Drug Store Products, Inc.

Lil' Drug Store Convenience Division provides a wide variety of products and merchandising vehicles to convenience stores, club stores, and other classes of trade nationwide. Retailers can find everyt...


Verseon is a technology-based pharmaceutical company that employs its proprietary computational drug discovery platform to develop novel therapeutics for today’s challenging ...

National Association of Chain Drug Stores

Founded in 1933 by six chain executives, the National Association of Chain Drug Stores worked to provide the chain drug industry with a unified voice necessary for growth and success. More than 70 yea...

Epic Therapeutics Incorporated

Epic Therapeutics, Inc. has developed a proprietary, protein-matrix drug delivery technology, ProMaxx®, that is produced entirely in water and is substantially more versatile and cost-effective at so...

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