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Researchers in the U.S. and U.K. have uncovered a link between an antimicrobial toxin that is produced by common gut bacteria to fend off their rivals and inflammatory bowel disease (IBD). The studies...
Felids are the only definitive hosts of Toxoplasma gondii. To lay a foundation for screening the T. gondii-felids interaction factors, we have developed a reproducible primary culture method for cat i...
Rationale-endothelial cells (ECs) play important roles in various regeneration processes and can be used in a variety of therapeutic applications, such as cardiac regeneration, gene therapy, tissue-en...
Three-dimensional (3D) pseudoislets (PIs) can be used for the study of insulin-producing β-cells in free-floating islet-like structures similar to that of primary islets. Previously, we demonstrated ...
Genome-wide association studies have identified risk loci associated with the development of inflammatory bowel disease, while epidemiological studies have emphasized that pathogenesis likely involves...
The caspase activation and recruitment domain (CARD)-based inflammasome sensors NLRP1b and NLRC4 induce caspase-1-dependent pyroptosis independent of the inflammasome adaptor ASC. Here, we show that N...
has been founded in 1960 as a research institution of the Latvian Academy of Sciences. The founder and the first director (from 1960 till 1992) of IECS was Professor Eduard Yakubaitis. Since 1997 IECS...
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