ENBREL Company Profile

13:12 EDT 20th March 2018 | BioPortfolio

ENBREL is a type of protein called a tumor necrosis factor (TNF) blocker that blocks the action of a substance your body's immune system makes called TNF. People with an immune disease, such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and psoriasis, have too much TNF in their bodies. ENBREL can reduce the amount of TNF in the body to normal levels, helping to treat your disease. But, in doing so, ENBREL can also lower the ability of your immune system to fight infections.All medicines have side effects, including ENBREL. Possible side effects of ENBREL include:Serious infections
Many occurred in people prone to infection, such as those with advanced or poorly controlled diabetes Some serious infections have been fatal


Thousand Oaks
United States of America



News Articles [33 Associated News Articles listed on BioPortfolio]

Japan/India joint venture set to file for novel Enbrel biosimilar

YL Biologics (YLB) has announced that a Phase III clinical trial of its investigational Enbrel (etanercept)…

Amgen introduces Enbrel Mini single-dose cartridges with reusable auto-injector

Amgen has announced the US launch of Enbrel Mini single-dose prefilled cartridge with AutoTouch reusable autoinjector tp provide additional administration option for Enbrel (Etanercept) users.

Biosimilar shows equivalent efficacy to Enbrel

A Korean study in the Annals of the Rheumatic Diseases found LBEC0101, a biosimilar to Enbrel, or etanercept, was comparable  -More- 

Amgen Launches the Enbrel Mini Reusable Autoinjector That is Ergonomically Designed for Patients

THOUSAND OAKS, Calif., Nov. 17, 2017 /PRNewswire/ — Amgen (NASDAQ: AMGN) announced that the ENBREL Mini™ with AutoTouch™ is now available in the United States (U.S.). Awarded the Arthritis F...

New Warning for Arthritis Drug Enbrel

FDA is advising physicians about new safety concerns regarding the use of etanercept (Enbrel), a product recently approved to treat moderate to severe rheumatoid arthritis (RA)...

Prefilled Drug Cartridge Launched To Treat Arthritis, Other Chronic Conditions

NewsErgonomically designed reusable autoinjector provides an additional administration option for Enbrel (etanercept) users. The new Enbrel Mini with AutoTouch was approved by the FDA in September 201...

Amgen Launches The ENBREL Mini™ Single-Dose Prefilled Cartridge With AutoTouch™ Reusable Autoinjector That Is Ergonomically Designed For Patients

Innovative Reusable Autoinjector Provides Additional Administration Option for Enbrel® (Etanercept) Users Awarded Arthritis Foundation Ease of Use (SM) Commendation THOUSAND OAKS, Calif., Nov. 17,...

Enbrel biosimilar demonstrates comparable safety, efficacy in RA

Yeong Wook SongThe etanercept biosimilar, LBEC0101, demonstrated equivalent clinical efficacy and comparable safety profile to etanercept, and was well tolerated among patients with rheumatoid arthrit...

Drugs and Medications [2 Associated Drugs and Medications listed on BioPortfolio]

Enbrel [Physicians Total Care, Inc.]

These highlights do not include all the information needed to use Enbrel safely and effectively. See full prescribing information for Enbrel.Enbrel (etanercept)Solution for Subcutaneous UseInitial U.S...

Enbrel [Immunex Corporation]

These highlights do not include all the information needed to use Enbrel safely and effectively. See full prescribing information for Enbrel. Enbrel (etanercept)Solution for Subcutaneous UseInitial U....

PubMed Articles [3 Associated PubMed Articles listed on BioPortfolio]

Variability of intended copies for etanercept (Enbrel®): Data on multiple batches of seven products.

Fusion protein and monoclonal antibody-based tumor necrosis factor (TNF) inhibitors represent established treatment options for a range of inflammatory diseases. Regulatory authorities have outlined t...

Manufacturing history of etanercept (Enbrel(ࣨ)): Consistency of product quality through major process revisions.

Etanercept (ETN) (Enbrel®) is a soluble protein that binds to, and specifically inhibits, tumor necrosis factor (TNF), a proinflammatory cytokine. ETN is synthesized in Chinese hamster ovary cells by...

Blau-Jabs Syndrome in a Tertiary Ophthalmologic Center.

In a prospective case series of patients with Blau-Jabs syndrome (BJS) conducted in the Ophthalmology Department/Federal University of Sao Paulo, seven patients with clinical and ophthalmologic manife...

Clinical Trials [69 Associated Clinical Trials listed on BioPortfolio]

Canadian Assessment of Patient Outcomes and Effectiveness of Enbrel in Psoriasis

The purpose of this study is to evaluate the use of Enbrel® (etanercept) in the treatment of psoriasis in patients for a period of up to 1 year.

Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate Therapy

To investigate the changes in MRI-derived markers of joint inflammation and destruction and in biochemical markers of connective tissue metabolism and angiogenesis in rheumatoid arthritis ...

Study Evaluating the Safety and Efficacy of Enbrel (Etanercept) in Japan

The special use-results surveillance is conducted in patients who have never been treated with Enbrel and in whom its long-term therapy may be instituted in the actual setting of use after...

Study Evaluating Enbrel in Patients With Rheumatoid Arthritis

The purpose of this study is to investigate the incidence of adverse events for patients with rheumatoid arthritis treated with Enbrel under usual care settings. In addition, differences ...

Prospective Evaluation of the Radiographic Efficacy of Enbrel

It is known from the COMET-trial that patients who start Enbrel treatment early have a great chance of reaching clinical remission and radiographic nonprogression. It is still unclear, how...

Companies [3 Associated Companies listed on BioPortfolio]


ENBREL is a type of protein called a tumor necrosis factor (TNF) blocker that blocks the action of a substance your body's immune system makes called TNF. People with an immune disease, such as rheuma...

Enbrel® (etanercept)

Enbrel® (etanercept) is a TNF inhibitor approved for the following indications: moderately to severely active rheumatoid arthritis, polyarticular-course juvenile rheumatoid arthritis, psoriatic arthr...


VLST Corporation discovers and develops novel therapeutics for the treatment of inflammatory and autoimmune diseases. Disease areas in which the company’s technology may have utility include multip...

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Cytokine Tumour Necrosis Factor (TNF)
TNF is a compound that is classified as a cytokine which plays a central role in the cellular mechanisms of apoptosis or cell death. However, there are a number of different kinds of TNF, just under twenty, but the family of molecules have very similar a...

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