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Erimos Technologies, LLC Company Profile

19:34 EST 19th November 2017 | BioPortfolio

Erimos has exclusive license for nordihydroguaiaretic acid (NDGA) derivatives from The Johns Hopkins University. We have developed a novel process to extract NDGA from the resin of the leaves of Larrea tridentata, a desert plant indigenous to the southwestern US and Mexico. EM-1421, our lead candidate, is a semi-synthetic derivative of NDGA. It is designed to target specific differences between normal human cells and those cells that are abnormally aggressively dividing. Our goal is to develop effective medicines with a low toxicity profile for serious diseases with high unmet medical need. An intravenous formulation of EM-1421 is currently being evaluated for safety and effectiveness in a Phase I study in patients with solid tumors refractory to standard therapy. An intravaginal formulation of EM-1421 is in a Phase II pilot study evaluating its use for Cervical Intraepithelial Neoplasia (CIN). CIN, also called cervical dysplasia and squamous intraepithelial lesions (SIL) of the cervix, is the abnormal growth of epithelial tissue at the surface of the cervix, widely recognized as the precursor to cervical cancer. In addition, research is ongoing to develop an oral formulation of EM-1421 which could allow for sustained or combination therapy in oncology, and for convenient dosing for patients requiring chronic therapy.

Location

9600 Bellaire Blvd., Suite 228
Houston
Texas
77036
United States of America

Contact

Phone: (713) 541-2000
Fax: (713) 541-2005


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PubMed Articles [339 Associated PubMed Articles listed on BioPortfolio]

Health technology assessments conducted in health care facilities: A strategic practice? Findings from a content analysis of HTA reports.

In this paper, we test the hypothesis that health technology assessment units located in hospitals tend to be more optimistic toward technologies that are currently in use in their organization than t...

Enhancing the Gaming Experience Using 3D Spatial User Interface Technologies.

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A brief review of single-cell transcriptomic technologies.

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Technologies to Support Community-Dwelling Persons With Dementia: A Position Paper on Issues Regarding Development, Usability, Effectiveness and Cost-Effectiveness, Deployment, and Ethics.

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Clinical Trials [329 Associated Clinical Trials listed on BioPortfolio]

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Testing Latest Version of NidekRS3000Adv

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The mission of this project is to develop novel systems of care that can provide efficacious, scalable, cost-effective, participant friendly technology assisted behavioral interventions (T...

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