Synergy Pharmaceuticals, Inc. Company Profile

21:22 EST 16th December 2018 | BioPortfolio

Synergy is a biopharmaceutical company focused on the development of new drugs to treat gastrointestinal disorders and diseases. Synergy's proprietary drug SP-304 is a synthetic analog of the human gastrointestinal hormone uroguanylin, and acts by activating the guanylate cyclase C (GC-C) receptor on epithelial cells of the GI tract. SP-304 has completed a Phase I clinical trial in volunteers and is presently in a Phase 2a clinical trial of SP-304 in patients to treat chronic constipation. The Company expects to obtain topline data from this trial in 2010, and use those data to begin a Phase 2b 28-day repeated-oral-dose, placebo-controlled trial in SP-304 in CC patients in early 2011 and a Phase 2b 90-day repeated-oral-dose, placebo-controlled trial of SP-304 in IBS-C patients in the second quarter of 2011. More information is available at

News Articles [421 Associated News Articles listed on BioPortfolio]

Bausch Health makes $200m bid for bankrupt Synergy Pharmaceuticals

Canada-based Bausch Health Companies (previously Valeant Pharmaceuticals) has entered into a definitive agreement to acquire select assets of Synergy Pharmaceuticals...Read More... The post Bausch Hea...

Bausch Health Enters into a Definitive Agreement to Acquire Certain Assets of Synergy Pharmaceuticals

LAVAL, Quebec, Dec. 12, 2018 /PRNewswire/ — Bausch Health Companies Inc. (NYSE/TSX: BHC) (“Bausch Health” or the “Company”) announced today that it has entered into a def...

Bausch Health signs stalking horse agreement to buy Synergy Pharmaceuticals

Synergy filed a voluntary petition for reorganization under Chapter 11 of the U.S. Code (the Bankruptcy Code) with the US Bankruptcy Court for the Southern District of New The post Bausch Health sign...

Synergy Pharmaceuticals Announces License Agreement with Luoxin Pharmaceutical Group for TRULANCE (plecanatide) in China

Synergy Pharmaceuticals (NASDAQ:SGYP) announced today that the company has entered into a license agreement with Luoxin Pharmaceutical Group Shandong (Luoxin) providing Luoxin exclusive rights to deve...

Synergy Pharma Struggles Despite Promising Market Opportunities in 2019

After providing an update of its ongoing strategic review, New York-based Synergy Pharmaceuticals’ stock plunged more than 71 percent.

To Cover Debts, Synergy Inks $200M Bankruptcy Sale to Bausch Health

Synergy Pharmaceuticals has spent years looking for a buyer. The developer of a struggling drug for two types of chronic constipation finally has one—now that it’s gone bankrupt. New York-base...

Synergy Pharma Hit By Double Whammy, Shares Plunge 71%

Shares of Synergy Pharmaceuticals Inc. (SGYP) slumped over 71% in extended trading on Thursday, following a disappointing business update.

Bausch Health buy bankrupt Synergy Pharmaceuticals for $200m

Bankrupt drug developer Synergy Pharmaceuticals has announced that the company is to be acquired by Canadian speciality pharma firm Bausch Health for approximately $200 million in cash. The New York-b...

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PubMed Articles [232 Associated PubMed Articles listed on BioPortfolio]

The cooperation of pharmacologic-dose ascorbate with ceftriaxone against Staphylococcus aureus through bactericidal synergy and enhanced macrophage killing activity.

Ascorbate is a low-cost compound with a known bactericidal-synergy to antibitics. However, the synergy depends on concentrations and organisms. Thus, the synergy test by time-kill assay might be appro...

Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals.

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects ...

Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective.

Chiral pharmaceuticals (CPs), including non-steroid anti-inflammatory drugs (NSAIDs), β-blockers and some herbicide and pesticides, are widely used in aquaculture, clinical treatment and many other f...

Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: Hourly variation.

The removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency clos...

Synergy between chemical permeation enhancers and drug permeation across the tympanic membrane.

Chemical permeation enhancers (CPEs) can enable antibiotic flux across the tympanic membrane. Here we study whether combinations of CPEs (sodium dodecyl sulfate, limonene, and bupivacaine hydrochlorid...

Clinical Trials [322 Associated Clinical Trials listed on BioPortfolio]

A 2x2 Factorial Randomized Controlled Trial of Colchicine and Spironolactone in Patients With STEMI Who Have Undergone PCI With SYNERGY Stent Registry

The CLEAR SYNERGY trial will study the long term effects of three multidisciplinary treatments following PCI to treat ST elevation myocardial infarction. These treatments address both the ...

IRIS-Synergy Cohort in the IRIS-DES Registry

The purpose of this study is to evaluate the relative effectiveness and safety of Synergy stent compared to other drug eluting stents.

Safety and Performance Evaluation of CircuLite Synergy

The purpose of the study is to demonstrate the safety and functionality of the CircuLite Synergy Pocket Circulatory Assist Device.

Registry Experience at the Washington Hospital Center With Drug Eluting Stents - Synergy

To compare the incidence of major adverse cardiac events among a series of patients receiving the Synergy drug-eluting stent with bioabsorbable polymer to historical controls who have rece...

SYNERGY China: Assess SYNERGY Stent in China

Prospective, multicenter, single-arm study, enroll 100 patients in no more than 10 sites across China, the primary endpoint is Technical success.

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Synergy Pharmaceuticals, Inc.

Synergy is a biopharmaceutical company focused on the development of new drugs to treat gastrointestinal disorders and diseases. Synergy's proprietary drug SP-304 is a synthetic a...

Synergy Pharmaceuticals Inc.

Synergy Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development of new drugs to treat patients with gastrointestinal (GI) diseases and disorders. Synergyâ...

Synergy Health Concepts

The team at Pacific Interventionalists launched Synergy Health Concepts to focus specifically on CCSVI treatment and care. Chronic Cerebro-Spinal Venous Insufficiency (CCSVI) is c...

Synergy Strips Corp.

Synergy Strips Corp. (OTCQB:SNYR) is a consumer health care company, that is in the process of building a portfolio of best-in- class consumer product brands. Synergy's strategy i...

BIND Therapeutics and Synergy Pharmaceuticals

More Information about "Synergy Pharmaceuticals, Inc." on BioPortfolio

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Biopharmaceuticals are medical drugs produced using biotechnology. They include proteins (including antibodies), nucleic acids (DNA, RNA or antisense oligonucleotides) and living microorganisms like virus and bacteria where the virulance of viruses and b...

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