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GTC Biotherapeutics Company Profile

16:16 EDT 19th September 2018 | BioPortfolio

GTC Biotherapeutics develops, produces, and commercializes therapeutic proteins using transgenic animal technology. ATryn®, recombinant human antithrombin, is the first transgenically produced therapeutic protein approved anywhere in the world, having recently been approved by the European Commission (EMEA) for the prophylactic treatment of deep vein thrombosis in patients with hereditary antithrombin deficiency. ATryn® was approved for hereditary antithrombin deficiency in the United States (FDA) in February 2009, and remains the only recombinant form of the molecule available for clinical use. ATryn® is produced in the milk of goats using micro-injection technology to incorporate a human antithrombin transgene. In addition to ATryn®, GTC is developing additional recombinant proteins and monoclonal antibodies. These products have potential applications in hematology, oncology, and autoimmune diseases. GTC has active development and commercialization relationships with Lundbeck Inc. and LFB Paris.

Location

175 Crossing Blvd.
Framingham
Massachusetts
01702
United States of America

Contact

Phone: (508) 620-9700
Fax: (508) 370-3797


News Articles [232 Associated News Articles listed on BioPortfolio]

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Codexis Appoints Biotherapeutics R&D VP

Dr. Alaoui will be responsible for the biotherapeutics discovery pipeline and acceleration of drug candidates to the clinic

Cancer Research UK launches new research hub for biotherapeutics

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Pall and Celltheon form strategic biotherapeutics partnership

This partnership will deliver integrated manufacturing solutions for customers developing biotherapeutics

BRIEF—Eleven Biotherapeutics changes name to Sesen Bio

USA-based oncology specialist Eleven Biotherapeutics has announced that the company is changing its name…

Gene Biotherapeutics sells Excellagen technology platform to Olaregen

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Deals this week: Aeglea BioTherapeutics, BerGenBio, Evelo Biosciences

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SAB Biotherapeutics closes $10mm Series A-2 round

Infectious disease-focused SAB Biotherapeutics Inc. received $10mm in its Series A-2 financing from T. Denny Sanford, who joins SAB's board.

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Plasma Protein Fraction (Human) 5%, USPPlasmanate®

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PubMed Articles [25 Associated PubMed Articles listed on BioPortfolio]

Synthetic Biology and Engineered Live Biotherapeutics: Toward Increasing System Complexity.

Recent advances in synthetic biology and biological system engineering have allowed the design and construction of engineered live biotherapeutics targeting a range of human clinical applications. In ...

Cell Penetration Profiling Using the Chloroalkane Penetration Assay.

Biotherapeutics are a promising class of molecules in drug discovery, but they are often limited to extracellular targets due to their poor cell penetration. High-throughput cell penetration assays ar...

Integrated BioTherapeutics.

Live bacterial biotherapeutics in the clinic.

Glycosimilarity assessment of biotherapeutics 1: Quantitative comparison of the N-glycosylation of the innovator and a biosimilar version of etanercept.

The carbohydrate moieties on the polypeptide chains in most glycoprotein based biotherapeutics and their biosimilars play essential roles in such major mechanisms of actions as antibody-dependent cell...

Clinical Trials [4 Associated Clinical Trials listed on BioPortfolio]

Safety and Pharmacokinetics Study of Anthrax Immune Globulin Intravenous (AIGIV)

The purpose of this study is to: - evaluate the safety profile of a single intravenous administration of AIGIV (containing either 3.5 mg/kg, 7.0 mg/kg or 14.0 mg/kg anti-PA IgG) a...

A Study to Evaluate the Safety, Tolerability, and Efficacy of Subcutaneous Injections of Elamipretide (MTP-131) in Subjects With Genetically Confirmed Mitochondrial Disease Previously Treated in the Stealth BioTherapeutics SPIMM-201 Study

This is a Phase 2, randomized, double-blind, placebo-controlled crossover study which will enroll up to 36 subjects (anticipated) with genetically confirmed mitochondrial disease who have ...

The Effect of OASIS Ultra on Critical Sized Wound Healing

The aim of this study is to evaluate the speed and quality with which OASIS® Ultra (Healthpoint Biotherapeutics; Fort Worth, Texas) increases wound healing in the critical sized defect. ...

Personalized Immunotherapeutics for Antibiotic-resistant Infection

M. A. suffers from hypogammaglobulinemia that has been complicated by refractory Mycoplasma hominis septic arthritis. He has been receiving the antibiotic valnemulin under Emergency Invest...

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More Information about "GTC Biotherapeutics" on BioPortfolio

We have published hundreds of GTC Biotherapeutics news stories on BioPortfolio along with dozens of GTC Biotherapeutics Clinical Trials and PubMed Articles about GTC Biotherapeutics for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of GTC Biotherapeutics Companies in our database. You can also find out about relevant GTC Biotherapeutics Drugs and Medications on this site too.

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