High Throughput Genomics, Inc Company Profile

18:03 EDT 19th March 2018 | BioPortfolio

High Throughput Genomics (HTG) was founded to: Develop and market ArrayPlate measurement of gene expression, DNA and proteins.
Develop and market gene expression quantitative Nuclease Protection Assays (qNPA™).
Satisfy unmet needs encountered at all levels of drug discovery, clinical development, and clinical practice.
Other commercialized methods for drug discovery lack sensitivity and have poor reproducibility. As a result low and moderately expressed genes that change slightly but significantly in disease states cannot be identified accurately against background assay noise.
HTG introduced the ArrayPlate, its first qNPA product, to measure multiple gene expression targets simultaneously. The ArrayPlate combines the high sample throughput of traditional microplates with HTG's novel Universal Array™ technology, permitting investigators to customize the genes measured in each well using a simple bench-top[ reagent addition procedure, producing self-customized arrays. With the combination of these two technologies, researchers now have access to the excellent sensitivity required to detect small changes and weak activity and the reproducibility of conventional biochemical assays in a multiplexed format permitting the measurement of sets of from 2 to 128 or more genes for high volume profiling of gene expression. In practical terms, this combination provides sensitivity down to 1,000 cells on 0.01 micrograms of total RNA and exceptional reproducibility of 3% to 13% coefficient of variation (C.V.) across the entire assay for cellular in vitro and in vivo tissue assays. The ability to easily measure gene expression from fixed tissue with the same high quality as from cells or frozen tissue is unique to qNPA


6296 E. Grant Road
United States of America


Phone: (520) 547-2827
Fax: (520) 547-2837

News Articles [956 Associated News Articles listed on BioPortfolio]

healthcare, bioinformatics, molecular evolution, chemoinformatics, antisense, tissue sealants

Provider,of,conferences, and, publications, on, combinatorial, chemistry, high, throughput, screening, bioinformatics, drug, discovery, and, genomics

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High Throughput PARP Screening Assay

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Unchained Labs Lunatic batch quantification system for proteomics and genomics

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Google releases AI tool for understanding the human genome

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Berry Genomics Collaborates with 10X Genomics for Next-Gen Prenatal Tests

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PubMed Articles [1831 Associated PubMed Articles listed on BioPortfolio]

Synthetic genomics: the art of design and synthesis.

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Clinical Trials [2631 Associated Clinical Trials listed on BioPortfolio]

High Throughput Drug Sensitivity and Genomics Data in Developing Individualized Treatment in Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia

This pilot clinical trial studies whether using high throughput drug sensitivity and genomics data is feasible in developing individualized treatment in patients with multiple myeloma or p...

High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia

This clinical trial studies the feasibility of choosing treatment based on a high throughput ex vivo drug sensitivity assay in combination with mutation analysis for patients with acute le...

Screening for Genes in Patients With Congenital Neutropenia

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Contribution of High-throughput Exome Sequencing in the Diagnosis of the Cause Fetal Polymalformation Syndromes

This research concerns the contribution of a new examination, high-throughput exome sequencing, in the diagnosis of the cause of polymalformative fetal syndromes. With currently available ...

Improving Genetic Counseling for Patients With Spina Bifida Using Next Generation Sequencing

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