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High Throughput Genomics, Inc Company Profile

14:13 EDT 19th June 2018 | BioPortfolio

High Throughput Genomics (HTG) was founded to: Develop and market ArrayPlate measurement of gene expression, DNA and proteins.
Develop and market gene expression quantitative Nuclease Protection Assays (qNPA™).
Satisfy unmet needs encountered at all levels of drug discovery, clinical development, and clinical practice.
Other commercialized methods for drug discovery lack sensitivity and have poor reproducibility. As a result low and moderately expressed genes that change slightly but significantly in disease states cannot be identified accurately against background assay noise.
HTG introduced the ArrayPlate, its first qNPA product, to measure multiple gene expression targets simultaneously. The ArrayPlate combines the high sample throughput of traditional microplates with HTG's novel Universal Array™ technology, permitting investigators to customize the genes measured in each well using a simple bench-top[ reagent addition procedure, producing self-customized arrays. With the combination of these two technologies, researchers now have access to the excellent sensitivity required to detect small changes and weak activity and the reproducibility of conventional biochemical assays in a multiplexed format permitting the measurement of sets of from 2 to 128 or more genes for high volume profiling of gene expression. In practical terms, this combination provides sensitivity down to 1,000 cells on 0.01 micrograms of total RNA and exceptional reproducibility of 3% to 13% coefficient of variation (C.V.) across the entire assay for cellular in vitro and in vivo tissue assays. The ability to easily measure gene expression from fixed tissue with the same high quality as from cells or frozen tissue is unique to qNPA

Location

6296 E. Grant Road
Tucson
Arizona
85712
United States of America

Contact

Phone: (520) 547-2827
Fax: (520) 547-2837
Email: info@htgenomics.com


News Articles [894 Associated News Articles listed on BioPortfolio]

Creating an Automated High-Throughput Flow Cytometry System

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High Throughput PARP Screening Assay

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Developing a High Throughput Mass Spectrometry Platform for Drug Discovery

Prof. Jonathan Wingfield, AstraZeneca, describes the collaboration with Labcyte and Waters to develop a high throughput mass spectrometry platform.

high throughput screening, fluorescence polarization, analyst, immunoassay, microplates, well plates

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Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening

The authors of a new report illustrate how a magnetic nanoparticle assembly approach is used to increase throughput dramatically while reducing costs

Thermo Scientific and Evosep collaborate to develop and promote robust, high-throughput workflows for clinical proteomics

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Drugs and Medications [0 Results]

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PubMed Articles [1803 Associated PubMed Articles listed on BioPortfolio]

Chemical Genomics Translatability from Unicellular to Multicellular Models.

Chemical genomics has proven to be a useful and successful approach to study complex systems where conventional genetics fails to render feasible results. High-throughput phenotype screenings in model...

Automated growth rate determination in high-throughput microbioreactor systems.

The calculation of growth rates provides basic metric for biological fitness and is standard task when using microbioreactors (MBRs) in microbial phenotyping. MBRs easily produce huge data at high fre...

Applications of Support Vector Machine (SVM) Learning in Cancer Genomics.

Machine learning with maximization (support) of separating margin (vector), called support vector machine (SVM) learning, is a powerful classification tool that has been used for cancer genomic classi...

Droplet-based microfluidic analysis and screening of single plant cells.

Droplet-based microfluidics has been used to facilitate high-throughput analysis of individual prokaryote and mammalian cells. However, there is a scarcity of similar workflows applicable to rapid phe...

Change of Title: Microarrays Becomes High-Throughput.

MDPI's journal Microarrays released its first volume in 2012. Since then, the journal has published 129 articles on the topic of microarrays, including their applications, analysis and new development...

Clinical Trials [2757 Associated Clinical Trials listed on BioPortfolio]

High Throughput Drug Sensitivity and Genomics Data in Developing Individualized Treatment in Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia

This pilot clinical trial studies whether using high throughput drug sensitivity and genomics data is feasible in developing individualized treatment in patients with multiple myeloma or p...

High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia

This clinical trial studies the feasibility of choosing treatment based on a high throughput ex vivo drug sensitivity assay in combination with mutation analysis for patients with acute le...

Optimization of HIV-1 DNA Genotyping by High Throughput Sequencing to Document Antiretroviral Resistant Mutations

The analysis of HIV resistance to antiretrovirals (Sanger sequencing on RNA) is difficult when the viral load is undetectable or during therapeutic breaks. In these situations, the high th...

Screening for Genes in Patients With Congenital Neutropenia

Syndromic congenital neutropenia (SCN) includes a heterogeneous group of diseases characterized by congenital neutropenia associated with the involvement of other organs. Most patients hav...

Contribution of High-throughput Exome Sequencing in the Diagnosis of the Cause Fetal Polymalformation Syndromes

This research concerns the contribution of a new examination, high-throughput exome sequencing, in the diagnosis of the cause of polymalformative fetal syndromes. With currently available ...

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More Information about "High Throughput Genomics, Inc" on BioPortfolio

We have published hundreds of High Throughput Genomics, Inc news stories on BioPortfolio along with dozens of High Throughput Genomics, Inc Clinical Trials and PubMed Articles about High Throughput Genomics, Inc for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of High Throughput Genomics, Inc Companies in our database. You can also find out about relevant High Throughput Genomics, Inc Drugs and Medications on this site too.

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