The Immune Response Corporation Company Profile

15:00 EDT 20th June 2018 | BioPortfolio

The Immune Response Corporation (OTCBB: IMNR.OB) is an immuno-pharmaceutical company focused on developing products to treat autoimmune and infectious diseases. The Company’s lead immune-based therapeutic product candidates are NeuroVax™ for the treatment of MS and IR103 for the treatment of HIV infection. Both of these therapies are in Phase II clinical development and are designed to stimulate pathogen-specific immune responses aimed at slowing or halting the rate of disease progression.
NeuroVax™, which is based on the Company’s patented T-cell receptor (TCR) peptide technology, has shown potential clinical value in the treatment of relapsing forms of MS. NeuroVax™ has been shown to stimulate strong, disease-specific cell-mediated immunity in nearly all patients treated and appears to work by enhancing levels of FOXP3+ Treg cells that are able to down-regulate the activity of pathogenic T-cells that cause MS. Increasing scientific findings have associated diminished levels of FOXP3+ Treg cell responses with the pathogenesis and progression of MS and other autoimmune diseases such as rheumatoid arthritis (RA), psoriasis and Crohn’s disease. In addition to MS, the Company has open Investigational New Drug Applications (IND) with the FDA for clinical evaluation of TCR peptide-based immune-based therapies for RA and psoriasis


5931 Darwin Court
United States of America


Phone: 760-431-7080
Fax: 760-431-8636

News Articles [1329 Associated News Articles listed on BioPortfolio]

Nerve cells found to suppress immune response during deadly lung infections

(Harvard Medical School) Neurons that carry nerve signals to and from the lungs suppress immune response during fatal lung infections with the bacterium Staphylococcus aureus.Animal experiments show t...

Immune Response Tests Enable Rapid Antibiotic Decisions

A novel test uses quantitative multiplex gene expression to analyze a patient's immune system, or the host response, rather than...

Circulating Mitochondrial DNA Alerts Immune System to Danger

In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

Past exposures shape immune response in pediatric acute respiratory infections

(University of Pennsylvania School of Medicine) By analyzing immune cells of children who came to the emergency department with flu symptoms, researchers found that the suite of genes these early-resp...

Two Novel Immune-Response Clusters Identified to RSV

FRIDAY, May 18, 2018 -- Two novel immune-response clusters have been identified to respiratory syncytial virus (RSV), and they are associated with first- and second-year recurrent wheeze, according to...

Adaptive immune response: New cofactor of roquin identified

(Helmholtz Zentrum München - German Research Center for Environmental Health) Roquin has a key role in the adaptive immune response. It controls the activation and differentiation of T cells and thus...

EDs Should Be Aware of Immune-Related Adverse Events From Cancer Treatment

Immune checkpoint inhibitors are novel cancer therapeutics that enhance the anti-tumor immune response to various malignancies.

[Comment] Immunoscore for (colorectal) cancer precision medicine

Immunotherapies targeting immune checkpoints such as CTLA4, PDCD1 (PD-1), and CD274 (PD-L1) have revolutionised oncology.1 High-level microsatellite instability (MSI-high) caused by mismatch repair de...

PubMed Articles [3601 Associated PubMed Articles listed on BioPortfolio]

Immune System and Kidney Transplantation.

The immune system recognises a transplanted kidney as foreign body and mounts immune response through cellular and humoral mechanisms leading to acute or chronic rejection, which ultimately results in...

Rotavirus intestinal infection induces an oral mucosa cytokine response.

Salivary glands are known immune effector sites and considered to be part of the whole mucosal immune system. The aim of the present study was to assess the salivary immune response to rotavirus (RV) ...

The TCR Takes Some Immune Responsibility.

In this issue of Immunity, Van Braeckel-Budimmir et al. (2017) reveal that the pathogenic response of mice to a Plasmodium berghei infection is dominated by a Vβ8.1 T cell response. Mice lacking V...

Immune class regulation as an integrated response of factors related to host, stimulus and context.

Immune class regulation is the response of the immune system to infectious or non-infectious challenges to protect the host. This includes mounting of an appropriate immune response and subsequent res...

Live Imaging of the Skin Immune Responses: Visualization of the Contact Hypersensitivity Response.

A variety of immune cells are involved in cutaneous immune responses. Over the last decade, intravital imaging has become an important technique used to capture the dynamic behavior of immune cells in...

Clinical Trials [5503 Associated Clinical Trials listed on BioPortfolio]

Vitespen (HSPPC-96) for Immune Response Assessment Following Treatment of Resectable Renal Cell Carcinoma

The goal of this clinical research study is to learn if patients receiving HSPPC-96 after surgery have an immune response against kidney cancer and how long the immune system response may ...

Study of the Immune Response to Hepatitis C Virus

The purpose of this study is to investigate the mechanism of a successful immune response to hepatitis C virus (HCV) infection. Currently, it is believed that the immune system is involved...

Performance of the HBV ELISPOT in the Detection of the T Cellular Immune Response in Patients Infected by HBV or Cured

Activation of the immune system against a pathogen can be considered one of the most effective interventions in the field of infectious diseases. Transgene is developing a therapeutic vac...

Immune Durability After VSV-EBOV Vaccination

This prospective observational cohort study will follow the roughly 100 adults who received the VSV-ZEBOV vaccine in the Geneva phase 1 randomized controlled trial in 2014-2015 in order to...

Immune Response to Hepatitis C Virus

The purpose of the study is to investigate the immune response to hepatitis C virus to determine why some people clear the virus and others develop chronic infection. Changes in immune re...

Companies [1009 Associated Companies listed on BioPortfolio]

Immunitor Corporation Co., Ltd

Immunitor Corporation Co., Ltd., is the first private biotech company formed in Thailand Technology developed by Immunitor allows to formulate any desired immunogen or antigen as an or...

Inotrem S.A.

Inotrem is a biotechnology company specialized in the control of excessive immune response that occurs in acute inflammatory syndromes in the critical care setting. It has develop...

Checkmate Pharmaceuticals, Inc.

Checkmate Pharmaceuticals is a research and development company pursuing a novel approach to specifically activating the innate arm of the immune system to recognize and ultimatel...

IRX Therapeutics, Inc.

IRX Therapeutics is a clinical-stage company developing novel immunotherapies focused on reducing the immune suppression that is seen in the cancer tumor micro-environment, restor...

Pharmexa A/S

Pharmexa is a leading company in the field of therapeutic vaccines (pharmaccines) for the treatment of serious chronic diseases. Pharmexa’s proprietary AutoVac™ pharmaccine technology platform is ...

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Autoimmune Disorders
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