The Immune Response Corporation Company Profile

04:23 EST 19th December 2018 | BioPortfolio

The Immune Response Corporation (OTCBB: IMNR.OB) is an immuno-pharmaceutical company focused on developing products to treat autoimmune and infectious diseases. The Company’s lead immune-based therapeutic product candidates are NeuroVax™ for the treatment of MS and IR103 for the treatment of HIV infection. Both of these therapies are in Phase II clinical development and are designed to stimulate pathogen-specific immune responses aimed at slowing or halting the rate of disease progression.
NeuroVax™, which is based on the Company’s patented T-cell receptor (TCR) peptide technology, has shown potential clinical value in the treatment of relapsing forms of MS. NeuroVax™ has been shown to stimulate strong, disease-specific cell-mediated immunity in nearly all patients treated and appears to work by enhancing levels of FOXP3+ Treg cells that are able to down-regulate the activity of pathogenic T-cells that cause MS. Increasing scientific findings have associated diminished levels of FOXP3+ Treg cell responses with the pathogenesis and progression of MS and other autoimmune diseases such as rheumatoid arthritis (RA), psoriasis and Crohn’s disease. In addition to MS, the Company has open Investigational New Drug Applications (IND) with the FDA for clinical evaluation of TCR peptide-based immune-based therapies for RA and psoriasis


5931 Darwin Court
United States of America


Phone: 760-431-7080
Fax: 760-431-8636

News Articles [1441 Associated News Articles listed on BioPortfolio]

Team work and balance can keep a gut healthy

A signi

Childhood adversity increases susceptibility to addiction via immune response

(Elsevier) Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the ...

Researchers Focus on Putting the STING Back Into Immune Response

Recently, immuno-oncologists have turned their attention to the role of the second arm of the immune response—the more rough-and-ready innate arm, which serves as the body’s frontline defe...

Enzyme lays the foundations for allergic immune response

(Ruhr-University Bochum) While in search of the causes of allergies and asthma, a chance discovery has yielded new clues: researchers led by Dr Marcus Peters have ascertained that the enzyme guanylate...

Early childhood adversity increases sensitivity of the body's immune response to cocaine

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa...

IgM response against amyloid-beta in aging: a potential peripheral protective mechanism

The immune system plays a major role in the pathogenesis of age-related dementia, including Alzheimer’s disease (AD). An insight into age-associated changes in the immune response to amyloid-beta (A...

Live probiotics can re-balance the gut microbiome and modify immune system response

(Cello Health PR) New research published in the International Journal of Pharmaceutics demonstrates that 'good' bacteria in the live probiotic SymproveTM can successfully reach and colonise the gut, w...

Medical News Today: Vision loss in glaucoma may be due to immune response

Glaucoma is a condition that leads to progressive loss of vision, but its root causes remain unclear. New research says an immune response may be to blame.

PubMed Articles [3538 Associated PubMed Articles listed on BioPortfolio]

Progress in research of influence of gene polymorphisms on immune response.

Genes play an important role in the immune system response, and different gene loci may result in different vaccine immune response rates. This review focuses on the correlation between gene polymorph...

Immune response and within-host viral evolution: immune response can accelerate evolution.

The objectives of this paper are to explore the impact of immune response on within-host viral evolution towards higher Darwinian fitness and, in particular, to verify a hypothesis that immune respons...

The role of immune cells in atrial fibrillation.

Atrial fibrillation (AF) is the most common sustained arrhythmia, but its mechanisms are poorly understood. Recently, accumulating evidence indicates a link between immune response and AF, but the pre...

Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery.

Post-operative infections occur frequently following major surgery. The magnitude of the post-operative immune response is associated with an increased risk of post-operative infections, although the ...

Immune response mediated by Th1 / IL-17 / caspase-9 promotes evolution of periodontal disease.

Periodontitis is characterized by inflammatory mediators beyond T lymphocyte function and phenotype (Th1/Th2/Th17). The clinical diversity in periodontitis makes it difficult to characterize the immun...

Clinical Trials [6024 Associated Clinical Trials listed on BioPortfolio]

Vitespen (HSPPC-96) for Immune Response Assessment Following Treatment of Resectable Renal Cell Carcinoma

The goal of this clinical research study is to learn if patients receiving HSPPC-96 after surgery have an immune response against kidney cancer and how long the immune system response may ...

Study of the Immune Response to Hepatitis C Virus

The purpose of this study is to investigate the mechanism of a successful immune response to hepatitis C virus (HCV) infection. Currently, it is believed that the immune system is involved...

Performance of the HBV ELISPOT in the Detection of the T Cellular Immune Response in Patients Infected by HBV or Cured

Activation of the immune system against a pathogen can be considered one of the most effective interventions in the field of infectious diseases. Transgene is developing a therapeutic vac...

Immune Durability After VSV-EBOV Vaccination

This prospective observational cohort study will follow the roughly 100 adults who received the VSV-ZEBOV vaccine in the Geneva phase 1 randomized controlled trial in 2014-2015 in order to...

Immune Response to Hepatitis C Virus

The purpose of the study is to investigate the immune response to hepatitis C virus to determine why some people clear the virus and others develop chronic infection. Changes in immune re...

Companies [1042 Associated Companies listed on BioPortfolio]

Immunitor Corporation Co., Ltd

Immunitor Corporation Co., Ltd., is the first private biotech company formed in Thailand Technology developed by Immunitor allows to formulate any desired immunogen or antigen as an or...

Inotrem S.A.

Inotrem is a biotechnology company specialized in the control of excessive immune response that occurs in acute inflammatory syndromes in the critical care setting. It has develop...

Checkmate Pharmaceuticals, Inc.

Checkmate Pharmaceuticals is a research and development company pursuing a novel approach to specifically activating the innate arm of the immune system to recognize and ultimatel...

IRX Therapeutics, Inc.

IRX Therapeutics is a clinical-stage company developing novel immunotherapies focused on reducing the immune suppression that is seen in the cancer tumor micro-environment, restor...

Pharmexa A/S

Pharmexa is a leading company in the field of therapeutic vaccines (pharmaccines) for the treatment of serious chronic diseases. Pharmexa’s proprietary AutoVac™ pharmaccine technology platform is ...

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