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Inte:Ligand Company Profile

10:11 EDT 25th June 2018 | BioPortfolio

The discovery of suitable lead structures for new drugs from an inexhaustibly large reservoir of theoretically possible compounds (order of magnitude: 10100) is one of the biggest challenges for the pharmaceutical industry. The search for the "needle in the haystack" (a drug candidate) nowadays is often performed by using high throughput screening (HTS), neglecting that even high-throughput methods can only cover an extremely small fraction of all possibilities. Inte:Ligand has developed methods to create new drug candidates and assess their development risks in a rational way.

Location

Mariahilferstrasse 74B/11
Vienna
1070
Austria

Contact

Email: office@inteligand.com.


News Articles [112 Associated News Articles listed on BioPortfolio]

Inte bättre – bara dyrare

Höftproteser med mineralbeläggning håller inte längre än de utan. Det visar en registerstudie gjord vid Akademiska sjukhuset.

Impairment of Fas-ligand–caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death

Ooivant Licenses Diabetes Drug From Ligand Pharma

Ligand Pharmaceuticals is licensing LGD-6972, a glucagon receptor antagonist (GRA), to Roivant Sciences for $20 million.

Roivant Licenses Diabetes Drug From Ligand Pharma

Ligand Pharmaceuticals is licensing LGD-6972, a glucagon receptor antagonist (GRA), to Roivant Sciences for $20 million.

Ligand Pharmaceuticals Inc Q4 Income Climbs

WASHINGTON (dpa-AFX) - Ligand Pharmaceuticals Inc (LGND) released a profit for its fourth quarter that increased from last year.The company said its bottom line climbed to $29.63 million, or $1.31...

Ligand In Deal With VenBio To Make OmniA Platform License Accessible

WASHINGTON (dpa-AFX) - Ligand Pharmaceuticals Inc. (LGND) said it has entered into an agreement with venBio Partners, a venture capital group focused on building and funding portfolio companies wi...

Scientists found a way to postpone cell death

(Lomonosov Moscow State University) A team of MSU-scientists and the Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences studied the mechanisms of interaction between t...

Ligand licenses diabetes program to Roivant Sciences

Active deal-maker Ligand Pharmaceuticals has granted Roivant Sciences exclusive global rights to develop…

PubMed Articles [636 Associated PubMed Articles listed on BioPortfolio]

Expanding the Library of Uranyl Amide Derivatives: New Complexes Featuring the tert-Butyldimethylsilylamide Ligand.

New uranyl derivatives featuring the amide ligand, -N(SiHMe)Bu, were synthesized and characterized by X-ray crystallography, multinuclear NMR spectroscopy, and absorption spectroscopies. Steric proper...

Structure determination of protein-ligand complexes by NMR in solution.

In this paper, we discuss methods for determining structures of protein-ligand complexes by NMR in solution. Our discussion is based on small ligands (< 2 kDa) as for example drugs, metabolites or oli...

Epsin-Dependent Ligand Endocytosis Activates Notch by Force.

DSL ligands activate Notch by inducing proteolytic cleavage of the receptor ectodomain, an event that requires ligand to be endocytosed in signal-sending cells by the adaptor protein Epsin. Two classe...

Ligand-Phospholipid Conjugation: a Versatile Strategy for Developing Long-Acting Ligands that Bind to Membrane Proteins by Restricting the Subcellular Localization of the Ligand.

We hypothesized that if drug localization can be restricted to a particular subcellular domain where their target proteins reside, the drugs could bind to their target proteins without being metaboliz...

Multiple binding modes of an unconjugated bis(pyridine) ligand stabilize low-valent Cp*Rh complexes.

The ligand 2,2'-bipyridine (bpy) can support metal centers in low formal oxidation states by delocalization of electron density into its π-system. We show that, in a model rhodium complex supported b...

Clinical Trials [193 Associated Clinical Trials listed on BioPortfolio]

Biological Therapy in Treating Patients With Metastatic Melanoma or Metastatic Kidney Cancer

RATIONALE: Biological therapies such as flt3L and CD40-ligand use different ways to stimulate the immune system and stop cancer cells from growing. Biological therapy may be an effective t...

A Phase III Trial of Recombinant Human Apo-2 Ligand for Injection

The trial is to evaluate the efficacy and safety of recombinant human Apo-2 ligand in treating patients with advanced retreated non-small cell lung cancer

Observational Study Evaluating the Quality of Pegasys and Copegus Treatment for Chronic Hepatitis C in Cooperation With the BNG (Association of German Resident Gastroenterologists)

This observational study will examine the efficacy and safety of Pegasys (pegint erferon alfa-2a), mostly in combination with Copegus (ribavirin) treatment in CH C patients. Quality of car...

Evaluation of PET/MRI Using a Somatostatin Analog Tracer as a Novel Approach to Detecting Pathology in High Risk TB-exposed Contacts

PET/MRI (positron emission tomography/magnetic resonance imaging) with somatostatin analog tracers has the potential to provide an imaging technique targeting subclinical granulomatous dis...

Evaluation of 11C-acetate PET Imaging as a Novel Approach to Detecting Pathology in Pulmonary TB

Imaging using 11C-acetate PET (positron emission tomography) in patients with tuberculosis (TB) may be able to detect non-replicating persister bacilli. This may permit identification of t...

Companies [41 Associated Companies listed on BioPortfolio]

Inte:Ligand

The discovery of suitable lead structures for new drugs from an inexhaustibly large reservoir of theoretically possible compounds (order of magnitude: 10100) is one of the biggest challenges for the p...

Ligand Pharmaceuticals

Ligand is an emerging specialty pharmaceutical company that discovers, develops and markets innovative small molecule drugs to address critical, unmet medical needs. Ligand markets four oncology and d...

Ligand Pharmaceuticals Incorporated

Ligand discovers and develops new drugs that address critical unmet medical needs of patients for a broad spectrum of diseases including hepatitis, muscle wasting, Alzheimer's, in...

Clinical Ligand Assay Society's

The Clinical Ligand Assay Society's mission is to establish and promote high standards in the science and application of ligand assay technology by encouraging research, educating practitioners, and f...

Neurogen Corporation & Ligand Pharmaceuticals

Ligand discovers and develops new drugs that address critical unmet medical needs of patients with muscle wasting, frailty, hormone-related diseases, osteoporosis, inflammatory di...

More Information about "Inte:Ligand" on BioPortfolio

We have published hundreds of Inte:Ligand news stories on BioPortfolio along with dozens of Inte:Ligand Clinical Trials and PubMed Articles about Inte:Ligand for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Inte:Ligand Companies in our database. You can also find out about relevant Inte:Ligand Drugs and Medications on this site too.

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