Inte:Ligand Company Profile

06:56 EST 20th November 2018 | BioPortfolio

The discovery of suitable lead structures for new drugs from an inexhaustibly large reservoir of theoretically possible compounds (order of magnitude: 10100) is one of the biggest challenges for the pharmaceutical industry. The search for the "needle in the haystack" (a drug candidate) nowadays is often performed by using high throughput screening (HTS), neglecting that even high-throughput methods can only cover an extremely small fraction of all possibilities. Inte:Ligand has developed methods to create new drug candidates and assess their development risks in a rational way.


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News Articles [147 Associated News Articles listed on BioPortfolio]

Inte bättre – bara dyrare

Höftproteser med mineralbeläggning håller inte längre än de utan. Det visar en registerstudie gjord vid Akademiska sjukhuset.

Ligand Pharma Makes Offer To Buy Vernalis For About $43 Mln In Cash

LONDON (dpa-AFX) - Ligand Pharmaceuticals Inc. (LGND)and Vernalis plc (VER.L) announce that Ligand has declared its firm intention to acquire the entire issued and to be issued shares of Vernalis ...

Ligand to buy UK biotech Vernaliss for $43 million

San Diego-based Ligand would acquire programmes in respiratory, oncology and CNS

M&As this week: Ligand Pharmaceuticals, CVS Health, Mundipharma

Ligand Pharmaceuticals has acquired Vernalis for $42.3m giving the former access to a portfolio of eight fully funded programmes, as...Read More... The post M&As this week: Ligand Pharmaceuticals...

With Vernalis Buy, Ligand Adds to Portfolio, Establishes U.K. Presence

Ligand Pharmaceuticals said Wednesday that its acquisition of U.K.-based biotech Vernalis has closed. The $42.3 million deal netted the San Diego company eight partner programs and a 70-person R&D...

WuXi Bio Pays $47 Million to Alter OmniAb Pact with Ligand Pharma

WuXi Biologics paid San Diego's Ligand Pharma $47 million in a single payment to re-negotiate its agreement for use of Ligand's OmniAb platform. Because of the payment, WuXi will not have to pay a per...

Ligand, WuXi Biologics Amend Agreement

Ligand has received $47M as a result of signing an amendment relating to its OmniAb platform agreement

#news #biotech Vernalis, weakened by FDA rejections, accepts £33M Ligand bid 

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Vernalis, weakened by FDA rejections, accepts £33M Ligand bid  .Ligand Phar...

PubMed Articles [647 Associated PubMed Articles listed on BioPortfolio]

Using Fluorescence Anisotropy for Ligand Binding Kinetics of Membrane Proteins.

Determining ligand binding kinetics provides an indirect route to probe the functional capabilities of the binding pocket of a membrane protein receptor. Presented in this unit are four ligand-binding...

Deprotonation of a formato ligand by a cis-coordinated carbyne ligand within a bis(phenolate) tungsten complex.

Deprotonation of a formato ligand by a cis-coordinated propylidyne ligand in a tungsten(vi) complex [(OSSO)W([triple bond, length as m-dash]CEt)(OCHO)] (3) that contains a tetradentate bis(phenolato) ...

Lanthanide Complexes with Photochromic Organoboron Ligand: Synthesis and Luminescence Study.

A novel, photochromic N^C-chelate organoboron functionalized dipicolinic acid (HL) has been designed and synthesized. Lanthanide(III) complexes based on this ligand (L) with the general formula [NBu][...

Adenine protonation enables cyclic-di-GMP binding to cyclic-GAMP sensing riboswitches.

In certain structural or functional contexts, RNA structures can contain protonated nucleotides. However, a direct role for stably protonated nucleotides in ligand binding and ligand recognition has n...

Intramolecular metal-ligand electron transfer triggered by co-ligand substitution.

The possibility of directed stimulation of intramolecular electron transfer between a metal and a redox-active ligand in a molecular coordination compound is the key to its application in molecular ca...

Clinical Trials [217 Associated Clinical Trials listed on BioPortfolio]

Soluble CD95 Ligand Role in the Pathophysiology of Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

The study aims at defining the role of soluble CD95 Ligand in the physiopathology of a rare group of inflammatory diseases: ANCA associated vasculitis. Soluble CD95 Ligand might have a pro...

Biological Therapy in Treating Patients With Metastatic Melanoma or Metastatic Kidney Cancer

RATIONALE: Biological therapies such as flt3L and CD40-ligand use different ways to stimulate the immune system and stop cancer cells from growing. Biological therapy may be an effective t...

A Phase III Trial of Recombinant Human Apo-2 Ligand for Injection

The trial is to evaluate the efficacy and safety of recombinant human Apo-2 ligand in treating patients with advanced retreated non-small cell lung cancer

Observational Study Evaluating the Quality of Pegasys and Copegus Treatment for Chronic Hepatitis C in Cooperation With the BNG (Association of German Resident Gastroenterologists)

This observational study will examine the efficacy and safety of Pegasys (pegint erferon alfa-2a), mostly in combination with Copegus (ribavirin) treatment in CH C patients. Quality of car...

Evaluation of PET/MRI Using a Somatostatin Analog Tracer as a Novel Approach to Detecting Pathology in High Risk TB-exposed Contacts

PET/MRI (positron emission tomography/magnetic resonance imaging) with somatostatin analog tracers has the potential to provide an imaging technique targeting subclinical granulomatous dis...

Companies [42 Associated Companies listed on BioPortfolio]


The discovery of suitable lead structures for new drugs from an inexhaustibly large reservoir of theoretically possible compounds (order of magnitude: 10100) is one of the biggest challenges for the p...

Ligand Pharmaceuticals

Ligand is an emerging specialty pharmaceutical company that discovers, develops and markets innovative small molecule drugs to address critical, unmet medical needs. Ligand markets four oncology and d...

Ligand Pharmaceuticals Incorporated

Ligand discovers and develops new drugs that address critical unmet medical needs of patients for a broad spectrum of diseases including hepatitis, muscle wasting, Alzheimer's, in...

Clinical Ligand Assay Society's

The Clinical Ligand Assay Society's mission is to establish and promote high standards in the science and application of ligand assay technology by encouraging research, educating practitioners, and f...

Neurogen Corporation & Ligand Pharmaceuticals

Ligand discovers and develops new drugs that address critical unmet medical needs of patients with muscle wasting, frailty, hormone-related diseases, osteoporosis, inflammatory di...

More Information about "Inte:Ligand" on BioPortfolio

We have published hundreds of Inte:Ligand news stories on BioPortfolio along with dozens of Inte:Ligand Clinical Trials and PubMed Articles about Inte:Ligand for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Inte:Ligand Companies in our database. You can also find out about relevant Inte:Ligand Drugs and Medications on this site too.

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Drug Discovery
Clinical Approvals Clinical Trials Drug Approvals Drug Delivery Drug Discovery Generics Drugs Prescription Drugs In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...

Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...

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