Infinity Pharmaceuticals Company Profile

15:16 EST 11th December 2018 | BioPortfolio

The mission of Infinity Pharmaceuticals, Inc. (NASDAQ: INFI) is to discover, develop, and deliver to patients best-in-class medicines for the treatment of cancer and related conditions. We have built a pipeline of innovative product candidates for multiple cancer indications, all of which represent proprietary applications of our expertise in small molecule drug technologies. We believe that our small molecule discovery and development capabilities, strategic partnerships, team of highly experienced management and scientists, and corporate culture form the basis of our potential long-term competitive advantage in seeking to deliver best-in-class medicines to patients. IPI-504, our lead product candidate, is currently being studied in two disease-focused Phase I clinical trials. IPI-504 is a proprietary, targeted cancer therapy that inhibits heat shock protein 90, or Hsp90. We believe that the inhibition of Hsp90 has broad therapeutic potential for patients with solid and hematological tumors, including cancers that are resistant to other drugs, and that our small molecule technologies and expertise have resulted in a drug candidate with the potential to be a best-in-class Hsp90 inhibitor. Our next most advanced program is directed against the Hedgehog cell signaling pathway. The Hedgehog pathway is believed to play a central role in allowing the proliferation and survival of certain cancer-causing cells, and is implicated in many of the most deadly cancers. We believe the application of our chemistry expertise has resulted in drug candidates that have the potential to be best-in-class systemic inhibitors of the Hedgehog pathway, actively interfering with its deleterious effects. The goal of our third program is to identify small molecule compounds that inhibit the Bcl-2 family of proteins. Using our proprietary small molecule drug discovery technologies, we have identified selective inhibitors of Bcl-2 and its related protein family member, Bcl-xL. We also have other research programs that target cancer and related conditions.


780 Memorial Drive
United States of America


Phone: 617-453-1000
Fax: 617-453-1001

News Articles [350 Associated News Articles listed on BioPortfolio]

Infinity Pharma Appoints Samuel Agresta Chief Medical Officer

Samuel Agresta has been appointed chief medical officer of Cambridge, MA-based Infinity Pharmaceuticals (NASDAQ: INFI). Agresta comes to Infinity from Agios Pharmaceuticals (NASDAQ: AGIO), where he wa...

Bristol-Myers, Infinity Pharma To Evaluate Opdivo In Combination With IPI-549

Bristol-Myers Squibb Co. (BMY) and Infinity Pharmaceuticals, Inc. (INFI) on Monday announced a clinical trial collaboration to evaluate Bristol-Myers Squibb's Opdivo in combination with Infinity's IPI...

Bristol-Myers Squibb and Infinity Pharmaceuticals Collaborate to Evaluate Opdivo in Combination with IPI-549 in Urothelial Cancer

NEW YORK & CAMBRIDGE, Mass.–(BUSINESS WIRE)–Bristol-Myers Squibb Company (NYSE: BMY) and Infinity Pharmaceuticals, Inc. (NASDAQ: INFI) today announced a clinical trial collaboration t...

Bristol-Myers and Infinity partner for trial of opdivo and IPI-549

Bristol-Myers Squibb Company and Infinity Pharmaceuticals have collaborated to conduct a Phase II MARIO-275 clinical trial to evaluate the effect of...Read More... The post Bristol-Myers and Infinity...

Infinity Reports Clinical and Translational Data from Expansion Cohorts of MARIO‑1 Phase 1b ...

CAMBRIDGE, Mass., Nov. 10, 2018 /PRNewswire/ -- Infinity Pharmaceuticals, Inc. (NASDAQ: INFI) announced that data to be presented today at the 33rd Annual Meeting of Read more...

BMS and Infinity trial immunotherapy combo in bladder cancer

Bristol-Myers Squibb has broadened a collaboration with Infinity Pharmaceuticals as it seeks to find combinations that boost the potency of its cancer immunotherapy, Opdivo. Along with its arch-rival...

Medtronic introduces Infinity OCT spinal system in US

The Infinity OCT system has been developed to simplify posterior cervical spine surgery. The spinal system is a complete procedural solution, which incorporates navigation and biologics with the The ...

Arcus, Infinity to evaluate two triple combination therapies in selected tumor types

Arcus Biosciences and Infinity Pharmaceuticals have entered into a clinical collaboration to evaluate two triple combination therapies in certain tumor types which typically show minimal response to c...

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PubMed Articles [152 Associated PubMed Articles listed on BioPortfolio]

Calibrating a paracatadioptric camera by the property of the polar of a point at infinity with respect to a circle.

Two methods are presented for calibrating a paracatadioptric camera. A sphere in 3D space is projected to two parallel circles on which two tangents of a point and its antipode are parallel on the uni...

Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals.

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects ...

Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective.

Chiral pharmaceuticals (CPs), including non-steroid anti-inflammatory drugs (NSAIDs), β-blockers and some herbicide and pesticides, are widely used in aquaculture, clinical treatment and many other f...

Horizon Hair of Extremal Black Holes and Measurements at Null Infinity.

It is shown that the conserved charges on the event horizon and the Cauchy horizon associated with scalar perturbations on extremal black holes are externally measurable from null infinity. This sugge...

Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: Hourly variation.

The removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency clos...

Clinical Trials [240 Associated Clinical Trials listed on BioPortfolio]

Clinical Evaluation of the Infinity DBS System

The purpose of this post market study is to support the chronic clinical performance of the Infinity Deep Brain Stimulation (DBS) Implantable Pulse Generator (IPG), DBS leads, extensions a...

INFINITY™Total Ankle Replacement Follow-up

Study Title INFINITY™Total Ankle Replacement Follow-up (ITAR) Study Design Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary/Unilateral and/or ...

UK Infinity, Post-Market Clinical Follow-up Study

Study Title UK Post-Market Clinical Follow-Up Of The INFINITY® Total Ankle System Study Design Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary...

Prospective Evaluation Comparing the Effects of Constant Current Versus Constant Voltage in Deep Brain Stimulation Using Hybrid Systems

This post-marketing evaluation has been designed to consistently investigate the subject's preference when switching from a Medtronic® constant voltage or constant current device to a St ...

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic®20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sep...

Companies [1353 Associated Companies listed on BioPortfolio]

Infinity Pharmaceuticals, Inc.

Infinity is an innovative drug discovery and development company seeking to discover, develop, and deliver to patients best-in-class medicines for difficult-to-treat diseases. Inf...

Infinity Info Systems

Founded in 1987, Infinity Info Systems develops customer relationship management (CRM) and business analytics solutions for clients in the financial, life sciences, business services, media and manufa...

Infinity Group

Infinity Group is an RMB fund pioneer and the leader in cross border China RMB and dollar private equity funds. It is also the founder of the Infinity IP Bank, the hub for IP deve...

Infinity Technology, Inc

We realize both IT and corporate management play vital roles in the success of an organization, but speak different languages. Infinity Technology, Inc. has crafted everything necessary to unite these...

Infinity Healthcare Services LLC

Infinity Healthcare Services, LLC is a healthcare company formed to own and operate medical Imaging equipment throughout the United States. The company works directly with hospita...

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