Molecular Neurolmaging,LLc Company Profile

09:41 EDT 21st September 2018 | BioPortfolio

MNI was founded in 2000 by Drs. Kenneth Marek and John Seibyl to create a unique clinical research company that combines excellence in clinical neuroscience with state-of-art imaging using custom radiopharmaceuticals for diagnosis and monitoring of neurological and neuropsychiatric disorders. This fusion of internationally-recognized expertise in the clinical and imaging arenas into a unified research-dedicated organization allowed MNI to efficiently develop and execute large-scale diagnosis, progression and disease monitoring trials that stress quantitative imaging outcome measures. Drs. Marek and Seibyl has previously established their collaboration while faculty at Yale University and founded MNI with twenty staff members with long-term experience in clinical imaging trials. MNI is a privately-held, limited liability company incorporated in the state of Connecticut. MNI has developed a number of strategic alliances and corporate partnerships and contracts with major pharmaceutical companies, including Pfizer, Novartis, Boehinger-Ingelheim, Cephalon, Lilly, and GE Healthcare, among othersMolecular NeuroImaging, LLC (MNI) is a neuroimaging services company specializing in the efficient application of scintigraphic biomarkers in drug development and clinical research for neurodegenerative and neuropsychiatric disorders. MNI provides services across the pre-clinical and clinical spectrum including radioligand development, design and implementation of Phase 1 to Phase 4 clinical imaging trials, and customized clinical imaging site coordination and management in multi-site imaging studies. Our strong emphasis is on using investigational radiotracers with quantitative imaging outcome measures as diagnostic tools and/or for assessing disease mechanism or progression. Our focus is on developing radioligands as tools for human research. Clinical imaging studies conducted at our research dedicated imaging center include initial human biodistribution and dosimetry assessment, imaging outcome measure validation, in vivo occupancy and displacement studies, and Phase IIb/III/IV multi-center clinical trials to assess diagnostic accuracy, disease mechanism, or disease progression. MNI also has experience in coordinating multi-site imaging studies. We have developed a comprehensive clinical imaging site coordination and management program including site selection and set-up, training and management, core imaging lab services to acquire and analyze multi-center quantitative imaging data, and data management and regulatory compliance services.


60 Temple Street Suite 8A
New Haven
United States of America


Phone: 203.401.4300
Fax: 203.789

News Articles [468 Associated News Articles listed on BioPortfolio]

The Molecular Autopsy: Not Ready Yet for Prime Time

Although I have always been a strong advocate for sophisticated molecular and genomic testing, I tend to get a severe case of indigestion when I see references to the molecular autopsy (see: Can Inter...

Molecular Health introduces MH Mendel to help geneticists in diagnosing hereditary diseases

Molecular Health, a leading biomedical company that is transforming molecular data into clinically actionable information for efficient and safer cancer treatment options based on its proprietary Data...

One Type Of Data Is Not Enough In Personalized Medicine

ArticleThe big challenge in cancer is that each patient's disease is different from a molecular point of view and has a unique set of molecular features that have led to its development, according to ...

Molecular switches are not just 'on' or 'off'

(Aarhus University) It is not always easy to see if a switch is on or off! A new study shows that the same can be true of a molecular switch. This knowledge gives a new insight into the molecular swit...

New Molecular Wires for Single-Molecule Electronic Devices

NewsScientists have designed a new type of molecular wire doped with organometallic ruthenium to achieve unprecedentedly higher conductance than earlier molecular wires.

Ratchet up the pressure: Molecular machine exploits motion in a single direction

(Osaka University) A Japanese research team led by Osaka University developed a 'ratchet-like molecular machine,' which promotes uni-directional molecular motion during reactions. Inspired by dumbbell...

News from Molecular & Cellular Proteomics

(American Society for Biochemistry and Molecular Biology) These are research highlights from Molecular & Cellular Proteomics: proteostasis and cancer in a collagen-deficient skin disease; chemical too...

All wired up: New molecular wires for single-molecule electronic devices

(Tokyo Institute of Technology) Scientists at Tokyo Tech designed a new type of molecular wire doped with organometallic ruthenium to achieve unprecedentedly higher conductance than earlier molecular ...

Drugs and Medications [2 Associated Drugs and Medications listed on BioPortfolio]

Nilandron [sanofi-aventis U.S. LLC]

NILANDRON (nilutamide)Tablets

Salsalate [Libertas Pharma, Inc.]

Salsalate Tablets, USP 500 and 750 mgRx Only

PubMed Articles [606 Associated PubMed Articles listed on BioPortfolio]

Electrostatic Gate Control in Molecular Transistors.

Molecular transistors, in which single molecules serve as active channel components in a three-terminal device geometry, constitute the building blocks of molecular scale electronic circuits. To demon...

pywindow: Automated Structural Analysis of Molecular Pores.

Structural analysis of molecular pores can yield important information on their behaviour in solution and in the bulk. We developed pywindow, a python package that allows for the automated analysis of...

Molecular imaging and molecular diagnostics: two sides of the same coin?

Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches.

The aim of this article is to discuss how allergen-specific immunotherapy (AIT) can be improved through molecular approaches. We provide a summary of next-generation molecular AIT approaches and of th...

Molecular Illustration in Research and Education: Past, Present, and Future.

2D illustration is used extensively to study and disseminate the results of structural molecular biology. Molecular graphics methods have been and continue to be developed to address the growing needs...

Clinical Trials [1311 Associated Clinical Trials listed on BioPortfolio]

The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI

The purpose of this study is to determine ticagrelor combining with low molecular weight heparin is effective and safe during PCI or not.

In Vivo EGFR Molecular Classification

The investigators developed 18F-MPG as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status.

Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the k...

Validation of a Molecular Prognostic Test for Eye Melanoma

Up to half of patients with ocular melanoma (also called iris, choroidal or uveal melanoma) develop metastasis. We have found that certain molecular features of the eye tumor can be detect...

LCC-CARIS-01: Molecular Profiling in Gynaecological Cancer

This is a pilot feasibility study assessing the use of a commercial molecular profiling service in the UK's National Health Service (NHS). The impact of knowledge of a patient's molecular ...

Companies [850 Associated Companies listed on BioPortfolio]

ABT Molecular Imaging

ABT Molecular Imaging is a medical imaging company marketing its Generator, a production platform which produces unit doses of molecular imaging drugs for positron emission tomogr...

HTG Molecular Diagnostics

HTG Molecular Diagnostics is a leading provider of molecular-based solutions for gene expression profiling, miRNA and mRNA measurement, translational medicine and diagnostic appli...

Natural Molecular Testing Corp.

Natural Molecular Testing Corporation (NMTC) is a privately-owned, high-complexity molecular testing facility. NMTC provides genetic testing services and resources for our clinica...

Boron Molecular Inc

Boron Molecular Pty Ltd (?Boron Molecular?) is a specialist fine chemicals manufacturing company providing unique building-block compounds and specialist chemistry services to the global pharmaceutica...

Molecular Diversity Preservation International

Molecular Diversity Preservation International (MDPI) is a Swiss based nonprofit organization for deposit and exchange of molecular and biomolecular samples. MDPI is also an open access publisher in c...

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Stress is caused by your perception of situations around you and then the reaction of your body to them. The automatic stress response to unexpected events is known as 'fight or flight'. Discovered by Walter Cannon in 1932, it is the release of h...

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Commercial and academic collaborations are used throughout the biotechnology and pharmaceutical sector to enhance research and product development. Collaborations can take the form of research and evaluation agreements, licensing, partnerships etc. ...

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