Molecular Insight Pharmaceuticals Company Profile

17:39 EST 15th December 2018 | BioPortfolio

Molecular Insight Pharmaceuticals, Inc. is focused on the research, development and commercialization of innovative molecular imaging pharmaceuticals and targeted radiotherapeutics to diagnose, treat and manage disease. The company's two lead compounds, Zemivaâ„¢ and Azedraâ„¢, are in advancing clinical programs. Molecular Insight has completed a Phase 2b clinical trial for its lead cardiology product candidate, Zemivaâ„¢ (Iodofiltic acid I 123, also known as BMIPP) and intends to begin a pivotal registration trial for Zemivaâ„¢ in the second half of 2006. Zemivaâ„¢ is a molecular imaging pharmaceutical in later stage clinical development for its first targeted indication to rapidly diagnose cardiac ischemia, or insufficient blood flow to the heart, in chest pain patients in the hospital emergency department setting. Approximately five to eight million patients in the United States present to emergency departments each year complaining of chest pain. Molecular Insight Pharmceuticals' lead oncology product candidate is a radiotherapeutic for cancer, Azedraâ„¢ (Ultratraceâ„¢ MIBG), an FDA-designated Orphan Drug with a Fast Track designation to treat metastatic neuroendocrine tumors. The company also has molecular imaging programs in cardiology, oncology and neurology. Molecular Insight's pipeline leverages proprietary technologies to target, visualize, treat and monitor disease.


160 Second Street
United States of America


Phone: 617.492.5554
Fax: 617.492.5664

News Articles [989 Associated News Articles listed on BioPortfolio]

Molecular switches are not just 'on' or 'off'

(Aarhus University) It is not always easy to see if a switch is on or off! A new study shows that the same can be true of a molecular switch. This knowledge gives a new insight into the molecular swit...

Studies provide insight into molecular changes prior to onset of arthritis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future...

New insight into molecular processes

(University of Freiburg) Freiburg researchers are applying 2D-spectroscopy to isolated molecular systems for the first time.

Insight into the molecular mechanism behind PEG-mediated stabilization of biofluid lipases

Forming 3D Neuronal Models of the Brain

In this interview, conducted at SfN 2018, Grischa Chandy from Molecular Devices provides insight on 3D imaging solutions for neuroscience research.

Vasopressin Receptor Antagonist – Pipeline Insight Report 2018 Featuring Astellas, Bayer, Biovie, Azevan Pharmaceuticals, Ferring & Roche –

DUBLIN–(BUSINESS WIRE)–The “Vasopressin Receptor Antagonist – Pipeline Insight, 2018” drug pipelines has been added to’s offering. ‘Vas...

Chitinase as 'burnt-bridge' Brownian monorail efficiently hydrolyzing recalcitrant biomass

(National Institutes of Natural Sciences) Serratia marcescens Chitinase A (SmChiA) is a molecular motor efficiently hydrolyzing recalcitrant crystalline chitin by moving on the surface processively. B...

Molecular Health introduces MH Mendel to help geneticists in diagnosing hereditary diseases

Molecular Health, a leading biomedical company that is transforming molecular data into clinically actionable information for efficient and safer cancer treatment options based on its proprietary Data...

PubMed Articles [1282 Associated PubMed Articles listed on BioPortfolio]

Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals.

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects ...

Impact of Pharmaceuticals on the Environment: Risk Assessment Using QSAR Modeling Approach.

An extensive use of pharmaceuticals and the widespread practices of their erroneous disposal measures have made these products contaminants of emerging concern (CEC). Especially, active pharmaceutical...

Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective.

Chiral pharmaceuticals (CPs), including non-steroid anti-inflammatory drugs (NSAIDs), β-blockers and some herbicide and pesticides, are widely used in aquaculture, clinical treatment and many other f...

Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: Hourly variation.

The removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency clos...

Dislocations in molecular crystals.

Dislocations in molecular crystals remain terra incognita. Owing to the complexity of molecular structure, dislocations in molecular crystals can be difficult to understand using only the foundational...

Clinical Trials [1996 Associated Clinical Trials listed on BioPortfolio]

Role of IL-37 Genetic Variants in Modulating Innate Immune Response to Periodontal Pathogens

This study will provide mechanistic insight into the underlying causes and molecular level pathogenesis of periodontal diseases. We will identify key mechanisms that confer risk and protec...

Bioequivalence Study of Torrent Pharmaceuticals Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic®20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sep...

Bioequivalence Study of Torrent Pharmaceuticals's Ltd's Nebivolol 20 mg Tablet

Subjects to compare the single dose bioavailability of Torrent's Nebivolol Tablets 20 mg and Bystolic 20 mg Tablets of Forest Pharmaceuticals Inc., USA. Dosing periods of studies were sepa...

Cognate Patient Care Insight Scale

Schizophrenia is a disease of young adults that affects 1% of the general population. According to numerous studies, it has been estimated that between 50% and 80% of patients with schizop...

Study Comparing Citalopram Hydrobromide Tablets 40 mg (Torrent Pharmaceuticals Ltd) and RLD Tablets 40 mg (Manufactured By Forest Pharmaceuticals Inc, Missouri) in 24+2 Normal Healthy Male Subjects in Fed Condition

- Objective: - The objective of this study is to compare the rate and extent of absorption of the Test Product, Citalopram Hydrobromide 40 mg (Torrent Pharmaceutical Li...

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Clincial Trials
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...

Cardiology is a specialty of internal medicine.  Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...

Cardiovascular disease (CVD)
Acute Coronary Syndromes (ACS) Blood Cardiovascular Dialysis Hypertension Stent Stroke Vascular Cardiovascular disease (CVD) includes all the diseases of the heart and circulation including coronary heart disease (angina...

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