Molecular Templates Inc. Company Profile

12:36 EST 14th December 2018 | BioPortfolio

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are aimed particularly at melanoma, prostate and other metastatic cancers. Such agents are derived from the sophisticated mutation and selection of Shiga-like toxin (SLT) variants using recombinant DNA and proprietary ‘applied proteomics’ technologies.
New SLT therapeutic agents are created via a systematic approach involving the generation of a large number of mutant SLT genetic sequences that form a permanent combinatorial DNA library. From the library, SLT mutant genes are expressed and the corresponding protein toxins are screened for their ability to kill cancer cell-lines, whilst leaving normal human cell-lines unharmed.


MaRS Centre, 101 College Street, Suite 150
M5H 3W4


Phone: 416 946 2875
Fax: 416 946 6529

News Articles [474 Associated News Articles listed on BioPortfolio]

Molecular Templates Spikes on Big Pharma Deal

Molecular Templates announced on Wednesday that it will develop a protein-based oncology therapy with Takeda Pharmaceutical. Its share price rose over 50 percent on the news. The post Molecular Templa...

5 Top Weekly NASDAQ Biotech Stocks: Molecular Templates on Top

Molecular Templates, Galectin Therapeutic, Chiasma, ZioPharm Oncology and Caladrius Biosciences were last week's top gainers on the NASDAQ Biotechnology Index. The post 5 Top Weekly NASDAQ Biotech St...

Takeda and Molecular Templates partner on protein-based cancer therapy

Takeda Pharmaceutical has signed a licence, development and commercialisation agreement with drug development firm Molecular Templates to co-develop protein-based treatments...Read More... The post Ta...

Partners Takeda and Molecular Templates pen new joint development deal

Takeda Pharmaceutical Co. Ltd. and Molecular Templates Inc. penned a new co-development deal surrounding CD38-targeted engineered toxin bodies (ETBs) for diseases, including multiple myeloma.

Molecular Templates and Takeda to Take On Multiple Myeloma in Deal Worth up to $632 Million

Shares of Molecular Templates are up more than 52 percent in premarket trading after the company announced it has struck a deal with pharma giant Takeda Pharmaceuticals that could be worth up to $632 ...

Public offering nets $42.4mm for Molecular Templates

Oncology firm Molecular Templates Inc. netted $42.4mm through a public offering of 8.2mm common shares at $5.50. The company is developing immunotoxins based on its engineered toxin bodies (ETB) platf...

Public offering nets $48.8mm for Molecular Templates

Oncology firm Molecular Templates Inc. netted $48.8mm through a public offering of 9.4mm common shares (including the overallotment) at $5.50. The company is developing immunotoxins based on its engin...

Deal Watch: Takeda Teams With Molecular Templates On Anti-CD38 Approach To Multiple Myeloma

Takeda and Molecular Templates will work to develop targeted engineered toxin bodies for multiple myeloma. Celgene decides against optioning OncoMed’s...   

Drugs and Medications [2 Associated Drugs and Medications listed on BioPortfolio]

Nilandron [sanofi-aventis U.S. LLC]

NILANDRON (nilutamide)Tablets

Salsalate [Libertas Pharma, Inc.]

Salsalate Tablets, USP 500 and 750 mgRx Only

PubMed Articles [727 Associated PubMed Articles listed on BioPortfolio]

Shadow Mask Templates for Site-Selective Metal Exchange in Magnesium Porphyrin Nanorings.

Molecular templates can be used in many different ways to control the outcome of chemical reactions. Here we present a new type of template-directed synthesis. We show that templates can be used as sh...

Assembly of multicomponent protein filaments using engineered subunit interfaces.

Exploiting the ability of proteins to self-assemble into architectural templates may provide novel routes for the positioning of functional molecules in nanotechnology. Here we report the engineering ...

Self-Assembled Monolayers as Templates for Linearly Nanopatterned Covalent Chemical Functionalization of Graphite and Graphene Surfaces.

A new approach for nanoscale covalent functionalization of graphite surfaces employing self-assembled molecular monolayers of n-alkanes as templating masks is presented. Linearly aligned aryl groups w...

Design of DNA rolling-circle templates with controlled fork topology to study mechanisms of DNA replication.

Rolling-circle DNA amplification is a powerful tool employed in biotechnology to produce large from small amounts of DNA. This mode of DNA replication proceeds via a DNA topology that resembles a repl...

Site-specific adsorption of aromatic molecules on a metal/ metal oxide phase boundary.

Nano-structured surfaces are ideal templates to control the self-assembly of molecular structures towards well-defined functional materials. To understand the initial adsorption process, we have inves...

Clinical Trials [1390 Associated Clinical Trials listed on BioPortfolio]

Study of Medical Student Use of Templates to Document Outpatient Asthma Care in Electronic Medical Record

The purpose of the study is to measure the effectiveness of a social marketing-based medical education intervention on student use of evidence-based templates for documenting outpatient as...

Accuracy of Dental Implant Placement Using Two Different CBCT-derived Templates

The main purpose of the present study is to evaluate the dental implant placement using two different CBCT-derived templates and to study the related factors that affect accuracy so as to ...

Sleeves Versus Sleeveless Template

To compare virtual planning accuracy of computer-assisted template-based implant placement using CAD/CAM stereolithographic surgical templates with or without metallic sleeves.Furthermore ...

The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI

The purpose of this study is to determine ticagrelor combining with low molecular weight heparin is effective and safe during PCI or not.

In Vivo EGFR Molecular Classification

The investigators developed 18F-MPG as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status.

Companies [878 Associated Companies listed on BioPortfolio]

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Molecular Templates, Inc.

Molecular Templates is a venture-backed biopharmaceutical company focused on the discovery and development of a new class of targeted biologic therapeutics called Engineered Toxin...

Molecular Templates Inc.

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are...

Goldfarb Branham LLP

ABT Molecular Imaging

ABT Molecular Imaging is a medical imaging company marketing its Generator, a production platform which produces unit doses of molecular imaging drugs for positron emission tomogr...

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