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Molecular Templates Inc. Company Profile

21:43 EDT 19th June 2018 | BioPortfolio

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are aimed particularly at melanoma, prostate and other metastatic cancers. Such agents are derived from the sophisticated mutation and selection of Shiga-like toxin (SLT) variants using recombinant DNA and proprietary ‘applied proteomics’ technologies.
New SLT therapeutic agents are created via a systematic approach involving the generation of a large number of mutant SLT genetic sequences that form a permanent combinatorial DNA library. From the library, SLT mutant genes are expressed and the corresponding protein toxins are screened for their ability to kill cancer cell-lines, whilst leaving normal human cell-lines unharmed.

Location

MaRS Centre, 101 College Street, Suite 150
Toronto
Ontario
M5H 3W4
Canada

Contact

Phone: 416 946 2875
Fax: 416 946 6529
Email: randal@moleculartemplates.com


News Articles [483 Associated News Articles listed on BioPortfolio]

Molecular Templates reverse merges with Threshold Pharmaceuticals

Molecular Templates Inc. and Threshold Pharmaceuticals Inc. have reversed merged to form a new entity, which will take the Molecular Templates name and focus on continued development of two key cancer...

Molecular Templates closes $40mm PIPE following reverse merger

Oncology firm Molecular Templates Inc. grossed $40mm through a private placement of 5.8mm units priced at $6.90. Each unit was comprised of one common share and a warrant to purchase 0.50 shares of co...

Molecular Templates Reports First Quarter 2018 Financial Results

Molecular Templates (Nasdaq:MTEM) a clinical-stage oncology company focused on the discovery and development of the company’s proprietary engineered toxin bodies (ETBs), which are differentiated, ta...

Takeda, Molecular Templates collaborate in oncology drug discovery

Takeda Pharmaceutical Co. Ltd., through its Millennium Pharmaceuticals division (now known as Takeda Oncology), and Molecular Templates Inc. (MTI) have agreed to collaborate on multi-target drug disc...

Molecular Templates enters $10mm debt facility with Perceptive; draws down $5mm

Molecular Templates Inc. (developing engineered toxin bodies as cancer therapeutics) closed a $10mm debt facility with Perceptive Advisors. The company drew down a $5mm term loan immediately, and will...

Molecular Templates to Present at the UBS Global Healthcare Conference

AUSTIN, Texas, May 15, 2018 (GLOBE NEWSWIRE) -- Molecular Templates, Inc. (Nasdaq:MTEM) (“Molecular”), a clinical-stage oncology company focused on the discovery and development of the company...

Molecular Templates reports Phase I data for NHL candidate

Molecular Templates, Inc. Reports First Quarter 2018 Financial Results

MT-3724 Phase Ib Ongoing; Combination Studies Expected to Start in 2H18 AUSTIN, Texas, May 14, 2018 (GLOBE NEWSWIRE) -- Molecular Templates, Inc. (Nasdaq:MTEM) (“Molecular”), a clinical-stag...

Drugs and Medications [2 Associated Drugs and Medications listed on BioPortfolio]

Nilandron [sanofi-aventis U.S. LLC]

NILANDRON (nilutamide)Tablets

Salsalate [Libertas Pharma, Inc.]

Salsalate Tablets, USP 500 and 750 mgRx Only

PubMed Articles [695 Associated PubMed Articles listed on BioPortfolio]

Shadow Mask Templates for Site-Selective Metal Exchange in Magnesium Porphyrin Nanorings.

Molecular templates can be used in many different ways to control the outcome of chemical reactions. Here we present a new type of template-directed synthesis. We show that templates can be used as sh...

A new technique of pedicle screw placement with the use of sequential multilevel navigation templates based on patient-specific 3D CT reconstruction model: applicability in spine deformity.

The technique of placement of pedicle screws has gradually improved, but even misplacement observed in 1.2 to 20% of cases, have appeared techniques fluoroscopic, tomographic and electromagnetic navig...

Site-specific adsorption of aromatic molecules on a metal/ metal oxide phase boundary.

Nano-structured surfaces are ideal templates to control the self-assembly of molecular structures towards well-defined functional materials. To understand the initial adsorption process, we have inves...

Evaluation of standardized and study-specific diffusion tensor imaging templates of the adult human brain: Template characteristics, spatial normalization accuracy, and detection of small inter-group FA differences.

Digital diffusion tensor imaging (DTI) templates of the adult human brain are commonly used in neuroimaging research, and their characteristics influence the accuracy of the application. However, a sy...

Combined Layer/Particle Approaches in Surface Molecular Imprinting of Proteins: Signal Enhancement and Competition.

Herein we report novel approaches to the molecular imprinting of proteins utilizing templates sizing around 10 nm and some 100 nm. The first step comprised synthesizing nanoparticles of molecularly im...

Clinical Trials [1248 Associated Clinical Trials listed on BioPortfolio]

Study of Medical Student Use of Templates to Document Outpatient Asthma Care in Electronic Medical Record

The purpose of the study is to measure the effectiveness of a social marketing-based medical education intervention on student use of evidence-based templates for documenting outpatient as...

Accuracy of Dental Implant Placement Using Two Different CBCT-derived Templates

The main purpose of the present study is to evaluate the dental implant placement using two different CBCT-derived templates and to study the related factors that affect accuracy so as to ...

The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI

The purpose of this study is to determine ticagrelor combining with low molecular weight heparin is effective and safe during PCI or not.

In Vivo EGFR Molecular Classification

The investigators developed 18F-MPG as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status.

Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the k...

Companies [864 Associated Companies listed on BioPortfolio]

Molecular Templates

Molecular Templates is a biopharmaceutical company focused on the discovery and development of targeted biologic therapeutics using its novel Engineered Toxin Bodies (ETB) platfor...

Molecular Templates, Inc.

Molecular Templates is a venture-backed biopharmaceutical company focused on the discovery and development of a new class of targeted biologic therapeutics called Engineered Toxin...

Molecular Templates Inc.

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are...

Goldfarb Branham LLP

ABT Molecular Imaging

ABT Molecular Imaging is a medical imaging company marketing its Generator, a production platform which produces unit doses of molecular imaging drugs for positron emission tomogr...

More Information about "Molecular Templates Inc." on BioPortfolio

We have published hundreds of Molecular Templates Inc. news stories on BioPortfolio along with dozens of Molecular Templates Inc. Clinical Trials and PubMed Articles about Molecular Templates Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Molecular Templates Inc. Companies in our database. You can also find out about relevant Molecular Templates Inc. Drugs and Medications on this site too.

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