Oligomer Oy Company Profile

17:19 EDT 24th September 2018 | BioPortfolio



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News Articles [4 Associated News Articles listed on BioPortfolio]

Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide

Amyloid oligomer interactions and polymorphisms: disease-relevant distinct assembly of α-synuclein and tau

Cognition Therapeutics Initiates NIA-Funded SNAP Study of Elayta™ to Measure Toxic Oligomer Displacement and Clearance in Alzheimer's Disease

Pittsburgh, June 05, 2018 (GLOBE NEWSWIRE) -- Cognition Therapeutics, Inc., a clinical stage neuroscience company focused on the development of innovative therapeutics for the treatment of Alzheime...

Alzheon Scientists Discover Endogenous Substance in Human Brain That Inhibits Formation of Toxic Beta Amyloid Oligomers, Key Driver of Alzheimer’s Disease

Publication Details Discovery of 3-Sulfopropanoic Acid, the Primary Metabolite of Tramiprosate and its Prodrug ALZ-801, in Cerebrospinal Fluid of Healthy Subjects as well as Alzhe...

Drugs and Medications [0 Results]


PubMed Articles [78 Associated PubMed Articles listed on BioPortfolio]

Preparation of a Well-Defined and Stable β-Barrel Pore-Forming Aβ42 Oligomer.

The formation of amyloid-β peptide (Aβ) oligomers at the cellular membrane is considered a crucial process that underlies neurotoxicity in Alzheimer's disease (AD). To obtain structural information ...

Effects of Oligomer Length, Solvents, and Temperature on the Self-Association of Aromatic Oligoamide Foldamers.

The effects of oligomer length, solvent, and temperature on the self-association of stably folded short aromatic oligoamide are probed. With large flat surfaces, these aromatic oligoamides undergo sta...

Oligo(Ethylene Glycol) Length Effect of Water-Soluble Ru-Based Olefin Metathesis Catalysts on Reactivity and Removability.

A study of reaction kinetics and removal efficiency of a family of ruthenium (Ru)-based olefin metathesis catalysts containing ethylene-glycol-oligomer-tethered N-heterocyclic carbene (NHC) ligands ha...

Revisiting the Vibrational and Optical Properties of P3HT : A Combined Experimental and Theoretical Study.

We demonstrate that DFT-based calculations can provide straightforward means to analyze the effect of aggregation on the optical properties of regioregular P3HT oligomers of different lengths (up to 2...

Hydrothermal Growth of Centimeter-Scale CuO Plates: Planar Chromium(III) Oligomer as a Facet-Directing Agent.

In this work, a simple hydrothermal method was developed to synthesize CuO plates in centimeter scale for the first time. Plates of up to 20 μm thickness and several square millimeters in area have b...

Clinical Trials [3 Associated Clinical Trials listed on BioPortfolio]

Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer's Disease

This is a multi‐center, Phase 1b, randomized, double‐blind, placebo‐controlled parallel‐group trial in adults with mild to moderate AD.

Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal Fluid

AVI-4020 Injection, a phosphorodiamidate Morpholino oligomer (PMO), was found to cross the blood-brain barrier during a study of patients with presumptive West Nile virus disease. AVI-4065...

Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD), a fatal muscle degenerative disorder, arises from mutations in the dystrophin gene. Antisense therapy with the use of antisense oligonucleotides (AON) ha...

Companies [5 Associated Companies listed on BioPortfolio]

Oligomer Oy


Bio-Synthesis, Inc.

Bio-Synthesis Inc was the first commercial company providing DNA and peptides in 1984. We specialize in custom peptide synthesis from small to large scale and we can help you design the optimal pepti...


PolyMedix is the leader in developing biomimetics - novel small molecule, oligomer and polymer protein-mimetic drugs for membrane protein and protein:protein targets. PolyMedix has a proven computatio...

BioChrom Labs, Inc

Established in 1990, BioChrom Labs, Inc., Indiana, USA, is dedicated to developing and manufacturing polymeric materials using patentable and proprietary technologies. HYDROCELL HPLC Columns and packi...

Sarepta Therapeutics

Innovative RNA-Based Technology; First-in-Class Therapeutics Sarepta Therapeutics – formerly AVI BioPharma – remains focused on developing first-in-class, RNA-based therapeutics to imp...

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