Onyx Scientific Limited Company Profile

03:37 EST 18th November 2018 | BioPortfolio

Onyx Scientific is one of the fastest growing pharmaceutical service companies in the UK.
We have more than 40 expert scientists specialising in drug development from medicinal chemistry to early stage GMP production. Our chemistry expertise has an industry leading reputation. If you are sourcing a partner for lead optimisation, process development and scale up synthesis, or just want excellent chemistry support, Onyx Scientific provides a partnership of the highest standard


Silverbriar Enterprise Park East
Tyne and Wear
United Kingdom


Phone: 44 (0)191 516 6516
Fax: 44 (0)191 516 6526

News Articles [470 Associated News Articles listed on BioPortfolio]

North East Pharma Firm Bolsters US Team

Sunderland-based chemistry expert Onyx Scientific has strengthened its US presence with the appointment of a Chicago-based business development director.  Dan Brisard will oversee the contract ma...

Chemistry Firm Boosts US Commercial Team

Sunderland-based chemistry specialist Onyx Scientific has further strengthened its US team with the appointment of another business development professional. Adam Moorhouse joins the contract res...

Amgen Acquiring US Cancer Drug Firm Onyx Pharmaceuticals

Amgen buying Onyx which was earlier targeted by Pfizer and Novartis as well.

'Ridiculous' (in a Good Way) Results With Novel Stent

Both BIONYX and SORT OUT IX trials showed Resolute Onyx and BioFreedom stents noninferior to the Orsiro device, but stent thrombosis with Resolute Onyx was called 'ridiculously low' by one commentator...

[Articles] Thin composite wire strut, durable polymer-coated (Resolute Onyx) versus ultrathin cobalt–chromium strut, bioresorbable polymer-coated (Orsiro) drug-eluting stents in allcomers with coronary artery disease (BIONYX): an international, single-b

The Resolute Onyx stent was non-inferior to Orsiro for a combined safety and efficacy endpoint at 1-year follow-up in allcomers. The low event rate in both groups suggests that both stents are safe, a...

Medtronic Announces One-Month DAPT Clinical Study in the U.S. and Japan with Resolute Onyx DES in High Bleeding Risk Patients

The Onyx ONE Clear Study Builds Upon Body of Clinical Evidence to Inform Individualized DAPT Duration Following Stent Procedures DUBLIN - September 10, 2018 - Medtronic plc (NYSE:MDT) ...

TCT: Studies Suggest Thin May not Always be In for DES

(MedPage Today) -- Resolute Onyx, BioFreedom on par with ultra-thin Orsiro stent

Medtronic Begins U.S. Study of Drug-Eluting Stents to Evaluate Treatment of Bifurcation Lesions in Patients with Coronary Artery Disease

Medtronic Received IDE Approval from FDA to Generate Clinical Evidence with Resolute Onyx DES to Support Future Application for Expanded Indication in U.S. DUBLIN - May 16, 2018 - Me...

PubMed Articles [529 Associated PubMed Articles listed on BioPortfolio]

Preoperative embolization of skull base meningiomas: Outcomes in the Onyx era.

Preoperative embolization may facilitate skull base meningioma resection, but its safety and efficacy in the Onyx era have not been investigated. In this retrospective cohort study, we evaluated the o...

Transarterial embolization of peripheral high-flow arteriovenous malformation with ethylene vinyl alcohol copolymer (Onyx): single-center 10-year experience.

High-flow arteriovenous malformations (AVMs) are complex vascular lesions for which transcatheter embolization is considered as first-choice treatment nowadays. Multiple embolizing agents have been de...

Case report Novel use of Pipeline stent device after inadvertent micro-catheter rupture during AVF Embolization: A Technical Note.

Onyx, a liquid embolic agent, is the mainstay of embolization treatment of arteriovenous malformation [AVM] or fistula [AVF]. Micro catheter retention in embolic cast is a well-known complication. Rup...

Transvenous balloon-assisted Onyx embolization of dural arteriovenous fistulas of hypoglossal canal.

This retrospective study summarized the technique aspects and effectiveness of transvenous balloon-assisted Onyx embolization treating selected dural arteriovenous fistulas of hypoglossal canal (HCDAV...

Embolization with Onyx of an arterial pseudoaneurysm with an arteriovenous fistula complicating a percutaneous nephrolithotomy: A case report and review of literature.

Percutaneous nephrolithotomy (PCNL) has proven very effective in the management of renal stones. However, complications are not so rare, and bleeding is one of the most worrisome; it has a reported in...

Clinical Trials [641 Associated Clinical Trials listed on BioPortfolio]

IRIS-Onyx Cohort in the IRIS-DES Registry

The purpose of this study is to evaluate the relative effectiveness and safety of Onyx stent compared to other (drug eluting stents) DES.

Effect and Efficacy of Onyx™, Zotarolimus-eluting Stent for Coronary Atherosclerosis

The objectives of this study are 1. To establish a prospective registry of the whole patients who received percutaneous coronary intervention with Resolute Onyx™ stent. ...

ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck Cancer

RATIONALE: A specially modified virus called ONYX-015 may be able to kill tumor cells while leaving normal cells undamaged. Drugs used in chemotherapy use different ways to stop tumor cell...

Study Comparing Onyx and TRUFILL in Brain Arteriovenous Malformations (AVMs)

Test whether AVMs treated with Onyx is equivalent to treatment with n-BCA. Success is defined as an AVM size reduction greater than 50%

RESOLUTE ONYX China Single Arm Study

It is a single arm clinical evaluation of safety and efficacy of the Medtronic Resolute Onyx™ zotarolimus-eluting coronary stent system in subjects who are eligible for percutaneous tran...

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