OTAVA, Ltd. offers unique Receptor-Based Target-Focused libraries. These libraries are created from an extensive compound stock collection (490,000 compounds) and a rigorous process of refinement that involves harnessing the most current methods of theoretical medicinal chemistry.
All of the Receptor-Based Target-Focused libraries of compounds are available in-house, and come with docking scores and values for drug-like properties.
Using Sharp Focusing approach, we could focus our combined 490,000-compound stock collection on your specific target(s), on an exclusive basis.
Our company can also create an exclusive receptor-based target-focused library based on your own collection of compounds!
We sell novel CK2 inhibitors developed by our scientists as well as potent and selective inhibitors of IKK-å, SIRT1, SIRT2, STAT3, JNK3, GSK-3, CDK9, HDAC, HIF-1, eEF-2 kinase, CFTR chloride channel & MORE. These compounds are available in milligram and gram quantities. We also sell intermediates on route to the synthesis of these compounds. Custom and bulk quotes for final products and intermediates are available too.
OTAVA offers unique ProHit compounds displaying inhibitory activity (< 1 uM for the most active compounds) against distinct protein kinases. The compounds of each Kinase ProHit set are free of Intellectual property and belong to the single chemical class. ProHit compound sets can be used in the development of drugs targeting protein kinase enzymes.
Contract research is one of the main activities of OTAVA.
We specialize in development and preparing fluorescent dyes mainly used in life sciences: Cell Biology, Biochemistry, Molecular Biology and Neuroscience. Years of experience enables us to serve our customers with products of excellent high quality at very competitive price level. More than 300 synthetic dyes of various classes covering the absorbance range 350-1100 nm are presented in the product list.
Our In-house Stock Collection contains more than 120,000 compounds and all compounds have undergone quality control to confirm their chemical structures. All compounds are for prompt delivery.
About 148,000 compounds are available from our Tangible Compounds collection. External compound suppliers are the main source of Tangible Compounds. ANY compound ordered from this library can be delivered in about 2-4 weeks. This is a unique opportunity to enrich your company's collection of compounds for screening purposes or to order new building blocks not available from other suppliers.
Our company offers about 75,000 Building Blocks in multi-gram quantities and purity higher than 95%. These diverse compounds could be used for high-throughput and combinatorial synthesis of pharmaceutical libraries or scale-up of lead compounds for further development.
Nuclear factor-κB (NF-κB) transcription factors represent a conserved family of proteins that regulate not only immune cells, but also heart cells, glial cells and neurons, playing a fundamental rol...
Monitoring the contamination level in aquatic environments and assessing the impact on aquatic life occurs throughout the world. In the present study, an approach based on a combination of biomarkers ...
OTAVA, Ltd. offers unique Receptor-Based Target-Focused libraries. These libraries are created from an extensive compound stock collection (490,000 compounds) and a rigorous process of refinement that...
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Drug Discovery Clinical Approvals
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are dis...