Phage Biotech Ltd. Company Profile

02:33 EST 14th December 2018 | BioPortfolio

Phage-Biotech Ltd. was incorporated in March 2000, as a new player in the emerging field of Phage Therapy. The Company’s mission is to develop proprietary Phage-based anti-infective therapeutics to combat the increasing number of antibiotic-resistant infections worldwide. The Company has two short-term strategic objectives:To identify and formulate proprietary topical Phage preparations from discovery through pre-clinical trials, with an initial focus on anti-Pseudomonas therapeutics, andTo develop and out-license proprietary reagents and buffers to promote Phage stability, adsorption, and infectivity of phage-based therapeutics.The Opportunity. Antibiotic resistant infectious diseases impose a significant burden on society, and surpass $30 billion in annual direct treatment costs in the U.S. alone. The high cost stems from several key factors: (1) Individuals infected with drug resistant organisms usually have a poor prognosis and are more likely to require hospitalization and (2) drug-resistant infections acquired in hospitals nearly triple the cost of hospital stays. The cost of antibiotic resistance is expected to grow larger as medical experts anticipate record increases of antibacterial resistance in the next decade.
Two factors emphasize the urgent need to continue research and development into new and innovative drugs for infectious diseases:Today’s escalating antibiotic crisis is the direct result of large scale and indiscriminant over-use of anti-infective drugs. Both the FDA and the CDC recognize that even if all antibiotic use were indeed to become appropriate, a mission almost impossible to achieve, resistance would not disappear. Pharmaceutical companies have exhausted the arsenal of known antibiotic classes. Currently, the launch of new antibacterial products usually includes stronger dose formulations of old antibiotic classes. This results in the development of more antibiotic resistant strains and increased resistance of current strains. New classes of antibiotics are desperately needed.Phage Therapy. Phage Therapy offers a new effective weapon to combat infectious diseases, for both resistant and sensitive bacteria strains. In Eastern Europe, Phage Therapy has been routinely used to treat a wide range of bacterial infections for over 70 years, with high efficacy and minimal side effects. Studies have demonstrated that commercial phage mixtures can achieve bacterial elimination in up to 80% or higher of clinical strains, a very high success rate compared to currently used new generation antibiotics, which typically reach only 60% success.


4 Pekeris St. Rabin Science Park


Phone: 972-8-9471837
Fax: 972-8-9471845

News Articles [1658 Associated News Articles listed on BioPortfolio]

#jobs #lifescience Paramount Recruitment: Phage Display Scientist – Cambridge – 9 months FTC

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Paramount Recruitment: Phage Display Scientist – Cambridge – 9 mo...

First phage therapy center in the U.S. signals growing acceptance

Phage therapy went out of fashion in the U.S. decades ago. Now a new center at the University of California, San Diego wants to revive it to combat antibiotic-resistant infections.

Phage therapy draws renewed interest to combat drug-resistant microbes

(Children's National Health System) In the face of growing antibiotic resistance and few antibiotics in the development pipeline, phages are drawing renewed research interest as a potential silver bul...

CRISPR-Cas3 Platform Developer Locus Biosciences Acquires EpiBiome Phage Technology

Locus Biosciences, a developer of CRISPR-Cas3-engineered precision antibacterial products, has acquired EpiBiome’s high-throughput bacteriophage phage discovery platform for an undisclosed price, in...

Antibiotic Development Question: Should A Phage Library Equal One Application?

FDA may have to take a personalized medicine approach when deciding how to classify a phage bank used to create...   

Turning a phage

(University of California - San Diego) With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in coll...

Viruses Are the Better Antibiotic

The development of alternative therapies to combat antibiotic-resistant bacteria has attracted more than €4 million in grants and private investments for Vienna-based biotech company PhagoMed Bioph...

Nobel Prize 2018: how the winning chemistry technique helped generate new cancer treatments

Science blog This year’s Nobel Prizes were big for cancer science. First, the Nobel Prize for Physiology or Medicine went to two scientists who laid the groundwork for immunotherapy. And then cam...

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Stelara [Janssen Biotech, Inc.]

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PubMed Articles [148 Associated PubMed Articles listed on BioPortfolio]

Host range and molecular characterization of a lytic Pradovirus-like Ralstonia phage RsoP1IDN isolated from Indonesia.

A lytic Ralstonia solanacearum-infecting phage designated Ralstonia phage RsoP1IDN was isolated from soil in Indonesia. The phage has a linear double-stranded DNA genome of 41,135 bp with 413-bp termi...

Bacteriophages on Dairy Foods.

This review focuses on the impact of bacteriophages on the manufacture of dairy foods. Firstly, the impact of phages of lactic acid bacteria in the dairy industry, where they are considered enemies, i...

Isolation and Complete Genome Sequence of a Novel Marinobacter Phage B23.

We used the double-agar layer method to isolate a novel Marinobacter marina bacteriophage, B23, from the surface water sample of the Bohai sea of China. There is some work to better understand the pha...

Synergistic effect of phage therapy using a cocktail rather than a single phage in the control of severe colibacillosis in quails.

Infections associated with avian pathogenic Escherichia coli (APEC) cause severe economic losses to the poultry industry. The study presented herein investigated the in vivo performance of a single ph...

Phage proteins are expressed on the surface of Neisseria gonorrhoeae and are potential vaccine candidates.

All Neisseria gonorrhoeae strains whose DNA sequences have been determined possess filamentous phage sequences representing their full genomes. The presence of filamentous phage DNA sequences in all s...

Clinical Trials [20 Associated Clinical Trials listed on BioPortfolio]

Evaluation and Detection of Facial Propionibacterium Acnes Bacteria and Phage

This multi-center, outpatient study will extract and evaluate the presence of facial P. acnes bacteria and phage strains using pore strips on up to 400 human subjects.

Ascending Dose Study of the Safety of AB-SA01 When Topically Applied to Intact Skin of Healthy Adults

This study will examine the safety of ascending doses of AB-SA01 when topically applied to intact skin of healthy adults.

A Phase 3 Clinical Trial for a Rabies Vaccine (Vero Cell) for Human Use in Healthy Chinese Subjects

The purpose of this single-centre, randomized, double-blind, parallel control, phase 3 study is to evaluate the safety and immunogenicity of a rabies vaccine (Vero Cell) for human use in h...

Phase I Hepatitis C Vaccine Trial of Virosome-formulated Peptides

Pevion Biotech has designed a therapeutic vaccine to treat patients who suffer from chronic hepatitis C virus infection. The vaccine is based on a combination of the PeviPRO and PeviTER pl...

Phage II Trial of Stathmin as Predictive Biomarker for TPF Induction Chemotherapy in OSCC

To investigate the predictive value of stathmin expression as a predictive biomarker in OSCC patients, who treated with TPF (docetaxel, cisplatin and 5-fluorouracil ) induction chemotherap...

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Phage Biotech Ltd.

Phage-Biotech Ltd. was incorporated in March 2000, as a new player in the emerging field of Phage Therapy. The Company’s mission is to develop proprietary Phage-based anti-infective therapeutics to ...

Adaptive Phage Therapeutics (APT)

Adaptive Phage Therapeutics, Inc. (APT) is a clinical-stage company founded to provide an effective therapeutic response to the global rise of multi-drug resistant (MDR) pathogeni...

Phage Biotechnology Corp

Phage Biotechnology Corporation (Phage) is a Delaware Corporation, incorporated in 1998 and headquartered in Las Vegas, Nevada. The company has a manufacturing plant in Irvine, California, with resear...

Vincogen Corporation

Vincogen Corporation is a RF ID Biochip company established in year 2000 and has developed a proprietary radio-frequency (RF) biochip platform and T4 Phage Display platforms for use in several applica...

Special Phage Services

Few inventions in science and medicine have had such a profound effect on human health as the discovery and subsequent development of antibiotics. Following their introduction during World War II ma...

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