Proteome Factory AG Company Profile

11:03 EDT 21st March 2018 | BioPortfolio

The Proteome Factory AG is a modern biotech company specialized in proteomics, protein analysis, target validation and bioinformatics. The proteomic key technology platform significantly increases the chances to identify new drug targets in emerging disease and biomarkers of disease state. Additionally, the finding of biomarkers significantly enhances the opportunities for individual disease treatment. The Proteome Factory AG has developed an R&D key technology platform in life sciences and biotechnology. This technology platform is continuously optimized regarding efficiency, quality, and quantity. Combination of the core technologies proteomics, protein analysis, target validation and bioinformatics enables Proteome Factory AG to offer most rapid and reliable analyses of all kind of protein containing samples including body fluids, cells, tissues, and plants. The innovative proteomics platform ensures high sensitive and simultaneous analyses of a vast amount of proteins.Reverse-Proteomics (pharmaco proteomics) facilitates investigation of molecular mode of action and toxicology of drugs and other compounds. Utilization and development of modern bioinformatic technologies are most relevant to the Proteome Factory AG. Integrated data mining and processing enhance quality and speed of interpretation.
Beside high resolution 2D electrophoresis (up to 60x30 cm) latest gel-free LC-MS based techniques are applied to proteome analysis. In combination with new prefractionation techniques low abundant proteins can be analyzed allowing the identification of new high potential targets and biomarkers (e.g. by depletion of albumin from serum samples or analysis of albumin-bound proteins). Furthermore combination of de novo peptide sequencing by state-of-the-art mass spectrometry, HPLC, N-terminal protein and peptide sequencing allows Proteome Factory a reliable identification of post translational modifications (e.g. phosphorylation) and characterization of proteins’ primary structure.
The Proteome Factory AG has filed several patents for proteomic techniques. Selective Peptide Exclusion Chromatography (SPEC) allows a significant reduction of sample complexity while its content of information is not affected. Metal coded tagging (MeCAT) is a novel class of labeling reagents allowing quantitative multiplex analyses of several complex protein samples at the same time. First time MeCAT allows absolute quantification of proteins and biomolecules at a very sensitive level and a linear dynamic detection range of up to 9 orders of magnitude. Thus MeCAT is much more powerful than alternative techniques like stable isotope tagging.




Phone: 49 (0)30 20616265
Fax: 49 (0)30 20616267

News Articles [151 Associated News Articles listed on BioPortfolio]

German team maps 1st-ever proteome of the human heart

The first-ever proteome of the healthy human

Heat Shock Protein Reports on Proteome Stress

Proper regulation of protein homeostasis (proteostasis) is essential to maintain cellular fitness. Proteome stress causes imbalance of the proteostasis, leading to various diseases represented by neur...

Factory CRO acquires MileStone Research Organization

Factory CRO, a leading global CRO focused on medical devices and IVDs, has announced the acquisition of MileStone Research Organization. MileStone, located in San Diego, specializes in clinical resear...

Proteome of the Human Heart Mapped for the First Time

NewsResearchers from the Max Planck Institute of Biochemistry (MPIB) and the German Heart Centre at the Technical University of Munich (TUM) have now determined which and how many individual proteins ...

'Hand of God' saved Indonesian teen from fatal factory fire

TANGERANG, Indonesia (AP) — The explosion came first, shocking 17-year-old Fitriyah and sending her running for the only exit of the Indonesian fireworks factory where she started work just the week...

Advanced Proteome Therapeutics to Attend 2017 BIO-Europe Conference to Discuss Partnership ...

Advanced Proteome Therapeutics to Attend 2017 BIO-Europe Conference to Discuss Partnership Initiatives with Leading Biotechnology Companies

An atlas of the heart: Proteome of the human heart mapped for the first time

(Technical University of Munich (TUM)) A healthy heart beats about two billion times during a lifetime - thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute...

Factory CRO acquires company, building US presence

Global contract research organisation with a focus on medical devices and IVDs, Factory CRO, has acquired MileStone Research Organization — a San Diego based company.

PubMed Articles [244 Associated PubMed Articles listed on BioPortfolio]

The effects of dusts of bartin cement factory on Taurus Cedar (Cedru libani A Rich.) seeds' germination.

The present study effects of pollutant particles from Bartın Cement Factory on development of seeds and leaves of Taurus Cedar (Cedrus libani Rich.) which in plantation area around the factory were e...

Adverse health effects of ferronickel manufacturing factory on local residents: An interrupted time series analysis.

The first ferronickel manufacturing factory of the Republic of Korea was opened in Gwangyang City on October, 23rd, 2008. There has been public concern regarding heavy metal dust blown from the factor...

Rescue workers and trauma: Assessing interaction among risk factors after a firework factory explosion.

This study investigates which factors had the biggest impact on developing distress in rescue workers who were involved in a firework factory explosion.

Proteome Heterogeneity in Colorectal Cancer.

Tumour heterogeneity is an important feature of colorectal cancer (CRC) manifested by dynamic changes in gene expression, protein expression, and availability of different tumour subtypes. Recent publ...

Evaluation of Viral Genome Copies Within Viral Factories on Different DNA Viruses.

This article describes a simple method of measuring the number of viral genomes within viral factories. For this purpose, we use three DNA viruses replicating in the cytoplasm of the infected cells: w...

Clinical Trials [39 Associated Clinical Trials listed on BioPortfolio]

Studying Exposure to Trichloroethylene in Factory Workers in Guangdong Province, China

RATIONALE: Exposure to trichloroethylene in the workplace may increase the risk of damaging white blood cells. Learning about the long-term effects of trichloroethylene exposure in factory...

Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia

The hypothesis of this study is that many plasma proteins are altered in concentration and structure in preeclampsia and the elucidation of these alterations will add to the poorly underst...

Effect of Exercise on Muscle Proteome Signature

The aim of the study is to investigate skeletal muscle proteome signature changes induced by exercise training in young men

Improving Anemia Status of Female Garment Workers in Bangladesh: An Evaluation of Pilot Intervention in Four Factories

The current study is aimed at evaluating nutrition interventions to be implemented for improving health and nutritional status of female garments workers in 4 selected garment factories in...

The Effects of Trout Fed With a Vegetable Based Feed on Cardiovascular Risk Markers and Plasma Proteome

Fish from the aquaculture sector constitutes an increasing part of the fish consumption in Denmark. The most important farmed fish in Denmark is the rainbow trout. Due to limited access of...

Companies [143 Associated Companies listed on BioPortfolio]

Proteome Factory AG

The Proteome Factory AG is a modern biotech company specialized in proteomics, protein analysis, target validation and bioinformatics. The proteomic key technology platform significantly increases the...

Procognia Ltd.

Procognia is helping to develop a fuller understanding of proteins as targets and as therapeutics. Utilising technologies based around proteins arrays, we provide both the means for unraveling disease...

Proteome Sciences plc

Proteome Sciences is a leading company in proteomics, a new scientific discipline which enables correlations to be drawn between the range of proteins produced by a cell or tissue, and the initiation ...

Factory CRO - Medical Devices Factory Reimbursement

Proteome Consult

Proteome Consult offers specific expertise concerning the design and management of proteomics studies. Proteome Consult can draw on extensive expertise relating to the investigation of mammalian tiss...

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