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Proteome Factory AG Company Profile

09:06 EDT 19th September 2018 | BioPortfolio

The Proteome Factory AG is a modern biotech company specialized in proteomics, protein analysis, target validation and bioinformatics. The proteomic key technology platform significantly increases the chances to identify new drug targets in emerging disease and biomarkers of disease state. Additionally, the finding of biomarkers significantly enhances the opportunities for individual disease treatment. The Proteome Factory AG has developed an R&D key technology platform in life sciences and biotechnology. This technology platform is continuously optimized regarding efficiency, quality, and quantity. Combination of the core technologies proteomics, protein analysis, target validation and bioinformatics enables Proteome Factory AG to offer most rapid and reliable analyses of all kind of protein containing samples including body fluids, cells, tissues, and plants. The innovative proteomics platform ensures high sensitive and simultaneous analyses of a vast amount of proteins.Reverse-Proteomics (pharmaco proteomics) facilitates investigation of molecular mode of action and toxicology of drugs and other compounds. Utilization and development of modern bioinformatic technologies are most relevant to the Proteome Factory AG. Integrated data mining and processing enhance quality and speed of interpretation.
Beside high resolution 2D electrophoresis (up to 60x30 cm) latest gel-free LC-MS based techniques are applied to proteome analysis. In combination with new prefractionation techniques low abundant proteins can be analyzed allowing the identification of new high potential targets and biomarkers (e.g. by depletion of albumin from serum samples or analysis of albumin-bound proteins). Furthermore combination of de novo peptide sequencing by state-of-the-art mass spectrometry, HPLC, N-terminal protein and peptide sequencing allows Proteome Factory a reliable identification of post translational modifications (e.g. phosphorylation) and characterization of proteins’ primary structure.
The Proteome Factory AG has filed several patents for proteomic techniques. Selective Peptide Exclusion Chromatography (SPEC) allows a significant reduction of sample complexity while its content of information is not affected. Metal coded tagging (MeCAT) is a novel class of labeling reagents allowing quantitative multiplex analyses of several complex protein samples at the same time. First time MeCAT allows absolute quantification of proteins and biomolecules at a very sensitive level and a linear dynamic detection range of up to 9 orders of magnitude. Thus MeCAT is much more powerful than alternative techniques like stable isotope tagging.

Location

Dorotheenstr.94
Berlin
D-10117
Germany

Contact

Phone: 49 (0)30 20616265
Fax: 49 (0)30 20616267
Email: info@proteomefactory.com


News Articles [124 Associated News Articles listed on BioPortfolio]

Alzheimer disease pathology and the cerebrospinal fluid proteome

Altered proteome profiles have been reported in both postmortem brain tissues and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with AD pathology, amyloid patholog...

GE creates ready-to-run factory for viral vector drugs

GE Healthcare has created a ‘factory-in-a-box’ facility for the production of viral vector-based drugs, including viral vector vaccines, oncolytic viruses,...Read More... The post GE creat...

Artificial leaf as mini-factory for medicine

(Eindhoven University of Technology) Using sunlight for sustainable and cheap production of, for example, medicines. The 'mini-factory' in the form of a leaf that chemical engineers from Eindhoven Uni...

Thermal Protein Profiling May Offer New Insights on Antibiotic Resistance

Scientists from the European Molecular Biology Laboratory (EMBL) say they have adapted an existing technique to study the melting behavior of proteins so that it can be used for the study of bact...

EU officials clash with Chinese firm on drug factory inspection

European medicines regulators have issued a notice that an ingredient for a generic brain cancer drug made in China does not meet manufacturing standards, after inspectors were refused entry to a fact...

Hengtong High Voltage manufactures the world's longest length of 500kV AC XLPE submarine power ...

The 18.15km of 500 kV XLPE submarine cable without factory joints successfully passed the complete Factory Acceptance Test on the 10 thMarch 2018. Read more...

Lonza's virus factory shows gene therapy's Texas-sized promise

ZURICH (Reuters) - Swiss drugmaker-for-hire Lonza is betting that trillions of customized viruses made at a giant factory in Texas will be the lucrative raw materials of a medical revolution.

DXC Technology Launches Analytics Migration Factory to Accelerate Global Client Workload Migration to Microsoft Azure

New factory model with advanced artificial intelligence and machine learning capabilities debuts in Bangalore, India, to help clients gain significantly greater value from their data and analytics...

PubMed Articles [239 Associated PubMed Articles listed on BioPortfolio]

Adverse health effects of ferronickel manufacturing factory on local residents: An interrupted time series analysis.

The first ferronickel manufacturing factory of the Republic of Korea was opened in Gwangyang City on October, 23rd, 2008. There has been public concern regarding heavy metal dust blown from the factor...

Merged Map of the Yeast Proteome.

A comprehensive reference map of protein abundances in budding yeast is generated by combining the 21 largest quantitative proteome datasets currently available for this model organism.

Comparison of the Rat and Human Dorsal Root Ganglion Proteome.

Dorsal root ganglion (DRG) are a key tissue in the nervous system that have a role in neurological disease, particularly pain. Despite the importance of this tissue, the proteome of DRG is poorly unde...

Analysis of PNGase F-resistant N-glycopeptides using SugarQb for Proteome Discoverer 2.1 reveals cryptic substrate specificities.

SugarQb (www.imba.oeaw.ac.at/sugarqb) is a freely available collection of computational tools for the automated identification of intact glycopeptides from high-resolution HCD MS/MS data-sets in the P...

Salivary proteome patterns of individuals exposed to High Altitude.

Identification of molecular signatures having key roles in hypobaric hypoxia by analysing the salivary proteome. Saliva holds a promising future in the search for new clinical biomarkers that are easi...

Clinical Trials [44 Associated Clinical Trials listed on BioPortfolio]

Studying Exposure to Trichloroethylene in Factory Workers in Guangdong Province, China

RATIONALE: Exposure to trichloroethylene in the workplace may increase the risk of damaging white blood cells. Learning about the long-term effects of trichloroethylene exposure in factory...

Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia

The hypothesis of this study is that many plasma proteins are altered in concentration and structure in preeclampsia and the elucidation of these alterations will add to the poorly underst...

Effect of Exercise on Muscle Proteome Signature

The aim of the study is to investigate skeletal muscle proteome signature changes induced by exercise training in young men

Improving Anemia Status of Female Garment Workers in Bangladesh: An Evaluation of Pilot Intervention in Four Factories

The current study is aimed at evaluating nutrition interventions to be implemented for improving health and nutritional status of female garments workers in 4 selected garment factories in...

The Effects of Trout Fed With a Vegetable Based Feed on Cardiovascular Risk Markers and Plasma Proteome

Fish from the aquaculture sector constitutes an increasing part of the fish consumption in Denmark. The most important farmed fish in Denmark is the rainbow trout. Due to limited access of...

Companies [144 Associated Companies listed on BioPortfolio]

Proteome Factory AG

The Proteome Factory AG is a modern biotech company specialized in proteomics, protein analysis, target validation and bioinformatics. The proteomic key technology platform significantly increases the...

Procognia Ltd.

Procognia is helping to develop a fuller understanding of proteins as targets and as therapeutics. Utilising technologies based around proteins arrays, we provide both the means for unraveling disease...

Proteome Sciences plc

Proteome Sciences is a leading company in proteomics, a new scientific discipline which enables correlations to be drawn between the range of proteins produced by a cell or tissue, and the initiation ...

Factory CRO - Medical Devices Factory Reimbursement

Proteome Consult

Proteome Consult offers specific expertise concerning the design and management of proteomics studies. Proteome Consult can draw on extensive expertise relating to the investigation of mammalian tiss...

More Information about "Proteome Factory AG" on BioPortfolio

We have published hundreds of Proteome Factory AG news stories on BioPortfolio along with dozens of Proteome Factory AG Clinical Trials and PubMed Articles about Proteome Factory AG for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Proteome Factory AG Companies in our database. You can also find out about relevant Proteome Factory AG Drugs and Medications on this site too.

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