Adnexus Therapeutics, Inc Company Profile

19:43 EDT 20th March 2018 | BioPortfolio

Adnexus Therapeutics, Inc. (formerly Compound Therapeutics, Inc.) is focused on generating vital medicines through the discovery, development, and commercialization of our broadly applicable new therapeutic class, AdNectins™.
AdNectins have the potential to become a dominant class of protein therapeutics, overcoming the limitations of current protein classes, including antibodies and soluble receptors. AdNectins are designed and optimized using PROfusion™, Adnexus' proprietary protein design technology that uniquely enables selection of molecules with ideal product characteristics. Together, AdNectins and PROfusion are a powerful combination that enables the design and production of product candidates with desired drug properties for a wide variety of targets and therapeutic areas.

Adnexus is developing a portfolio of AdNectin therapeutic products. Angiocept™ (CT-322), an AdNectin that inhibits the activation of human vascular endothelial growth factor receptor 2 (VEGFR-2), is Adnexus' first product that was designed using this proprietary approach. Angiocept (CT-322) is scheduled to begin Phase I clinical studies in oncology in 2006.

Adnexus Therapeutics is led by a management team and Board of Directors with extensive industry experience covering all aspects of building successful biopharmaceutical companies. Collectively, the team has developed and launched over 20 marketed biologic products. The Company is backed by four leading venture firms: Atlas Venture, Flagship Ventures, Polaris Venture Partners, and Venrock Associates.


100 Beaver Street
United States of America


Phone: (781) 891-3745
Fax: (781) 891-3796

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