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Prion Developmental Laboratories Company Profile

16:09 EDT 21st June 2018 | BioPortfolio

PDL is a late development stage company focused on rapid diagnostic tests for prion diseases using tissue, blood, serum, or other body fluids. Located in Buffalo Grove, Illinois, PDL manufactures its rapid tests according to the requirements of current Good Manufacturing Procedures (cGMP). PDL uses the technologies and facilities of Virotek LLC to produce high quality diagnostic products.
Robert B. Petersen, Ph.D., Executive Vice President and Chief Scientific Officer, has been in academic science for the past 18 years. Over the past ten years, he has studied human prion diseases at Case Western Reserve University as an Associate Professor. His work on the genetics of human prion disease has allowed him to develop an international reputation in the field and has facilitated the organization of the scientific team assembled by PDL.

Location

900 Asbury Drive
Buffalo Grove
Illinois
60089
United States of America

Contact

Phone: 847-634-6400
Fax: 847-634-0476


News Articles [322 Associated News Articles listed on BioPortfolio]

Mice study illustrates potential risks associated with prion transmission

Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations.

Microglia may play key role in slowing progression of prion diseases, research suggests

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have...

Transmission risk of familial human prion diseases to mice

Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations. To determine whether three of the unstudied mutations are transmissible, scientists e...

Prion protein is essential for the RE1 silencing transcription factor (REST)-dependent developmental switch in synaptic NMDA receptors

NIAID scientists assess transmission risk of familial human prion diseases to mice

(NIH/National Institute of Allergy and Infectious Diseases) Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations. To determine whether thre...

Microglia are key defenders against prion diseases

(NIH/National Institute of Allergy and Infectious Diseases) Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available,...

Researchers suggest microglia key defenders against prion diseases

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have...

Newly Created Prion Seen As Exciting Research Tool

A neurodegenerative disease research team has created an exciting new research tool by synthesizing a fully functional, infectious human prion,...

PubMed Articles [974 Associated PubMed Articles listed on BioPortfolio]

Mechanism of aggregation and membrane interactions of mammalian prion protein.

The cellular prion protein (PrP), which is present ubiquitously in all mammalian neurons, is normally found to be linked to the cell membrane through a glycosylphosphatidylinositol (GPI) anchor. The c...

Novel Amplification Mechanism of Prions through Disrupting Sortilin-Mediated Trafficking.

Conformational conversion of the cellular prion protein, PrP(C), into the abnormally folded isoform of prion protein, PrP(Sc), which leads to marked accumulation of PrP(Sc) in brains, is a key pathoge...

Anti - Prion Systems in Yeast and inositol polyphosphates.

The amyloid-based yeast prions are folded in-register parallel beta sheet polymers. Each prion can exist in a wide array of variants, with different biological properties resulting from different self...

A brief overview of the Swi1 prion-SWI+.

Prion and prion-like phenomena are involved in the pathology of numerous human neurodegenerative diseases. The budding yeast, Saccharomyces cerevisiae, has a number of endogenous yeast prions-epigenet...

Mammalian amyloidogenic proteins promote prion nucleation in yeast.

Fibrous cross-β aggregates (amyloids) and their transmissible forms (prions) cause diseases in mammals (including humans) and control heritable traits in yeast. Initial nucleation of a yeast prion by...

Clinical Trials [671 Associated Clinical Trials listed on BioPortfolio]

PRION-1: Quinacrine for Human Prion Disease

PRION-1 aims to assess the activity and safety of Quinacrine (Mepacrine hydrochloride) in human prion disease. It also aims to establish an appropriate framework for the clinical assessmen...

Enhanced CJD Surveillance in the Older Population

The purpose of this study to investigate if cases of Creutzfeldt-Jakob Disease (CJD) and other forms of prion disease are being missed in older adults living within Lothian.

Translating Evidence Based Developmental Screening Into Pediatric Primary Care

The purpose of this study is to examine the feasibility, acceptability and effectiveness of implementing the AAP's recommendation that clinicians provide developmental surveillance at all ...

The Role of the Coagulation Pathway at the Synapse in Prion Diseases

The study hypothesis is that that the deleterious effect of prions on the brain may be mediated (at least partially) by activation of serine proteases involved in the coagulation system. I...

Developmental Dyslexia and Functional Maturation of Auditory Cortex

Developmental dyslexia is a frequent learning disability. The aim of this study is to compare auditory evoked cortical responses to syllables and tones in developmental dyslexia and contro...

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Prion Developmental Laboratories

PDL is a late development stage company focused on rapid diagnostic tests for prion diseases using tissue, blood, serum, or other body fluids. Located in Buffalo Grove, Illinois, PDL manufactures its ...

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North Carolina Council on Developmental Disabilities

The North Carolina Council on Developmental Disabilities (NCCDD) works to assure that people with intellectual and other developmental disabilities (I/DD) and their families parti...

Georgia Council on Developmental Disabilities

GCDD is a federally funded, independent state agency that meets quarterly throughout Georgia to collaborate with citizens, public and private advocacy organizations, and policy makers to positively in...

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Chronix Biomedical is a functional genomics company whose products address the chronic disease markets both human and veterinary. The company's product line is based on its proprietary approach to dev...

More Information about "Prion Developmental Laboratories" on BioPortfolio

We have published hundreds of Prion Developmental Laboratories news stories on BioPortfolio along with dozens of Prion Developmental Laboratories Clinical Trials and PubMed Articles about Prion Developmental Laboratories for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Prion Developmental Laboratories Companies in our database. You can also find out about relevant Prion Developmental Laboratories Drugs and Medications on this site too.

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