Prion Developmental Laboratories Company Profile

13:32 EST 22nd January 2019 | BioPortfolio

PDL is a late development stage company focused on rapid diagnostic tests for prion diseases using tissue, blood, serum, or other body fluids. Located in Buffalo Grove, Illinois, PDL manufactures its rapid tests according to the requirements of current Good Manufacturing Procedures (cGMP). PDL uses the technologies and facilities of Virotek LLC to produce high quality diagnostic products.
Robert B. Petersen, Ph.D., Executive Vice President and Chief Scientific Officer, has been in academic science for the past 18 years. Over the past ten years, he has studied human prion diseases at Case Western Reserve University as an Associate Professor. His work on the genetics of human prion disease has allowed him to develop an international reputation in the field and has facilitated the organization of the scientific team assembled by PDL.


900 Asbury Drive
Buffalo Grove
United States of America


Phone: 847-634-6400
Fax: 847-634-0476

News Articles [263 Associated News Articles listed on BioPortfolio]

Researchers discover prion-like viral proteins that open new targets for antiviral drugs

Researchers at the Human Microbiology Institute and Tetz Laboratories have discovered thousands of prion-like domains in human viruses, prompting research that opens new ways of viral pathogenicity, ...

Possible molecular pathway for neurodegeneration in prion diseases

A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.

Not All Prion Strains Interfere with Each Other

NewsThe first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought.

BU researchers define possible molecular pathway for neurodegeneration in prion diseases

(Boston University School of Medicine) A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.

Possible Molecular Pathway for Neurodegeneration in Prion Diseases Defined

NewsA new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.

Prion Disease Harms Neurons via Stress Pathway

Prions beget prions, we know, but we lack a good understanding of prion diseases. We can follow the progress of prion diseases up to a certain point—the accumulation of misfolded proteins. To press ...

Discovering Prion-like Proteins in Eukaryotic Viruses

Dr. George Tetz discusses the discovery of prion-like domains in eukaryotic viruses, and the implications of this study on gene therapies and common neurological diseases such as Alzheimer's Disease.

Creutzfeldt-Jakob disease spreads prions throughout the eyes, researchers find

(American Society for Microbiology) Researchers recently studied the eyes of 11 people with sporadic Creutzfeldt-Jakob disease (sCJD), the most common and well-known prion disorder. This week in mBio,...

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PubMed Articles [977 Associated PubMed Articles listed on BioPortfolio]

Amyloid- and tau-PET imaging in a familial prion kindred.

To study the in vivo binding properties of F-AV-1451 (tau-PET) and Pittsburgh compound B (PiB-PET) in a unique kindred with a familial prion disorder known to produce amyloid plaques composed of prion...

A brief overview of the Swi1 prion-SWI+.

Prion and prion-like phenomena are involved in the pathology of numerous human neurodegenerative diseases. The budding yeast, Saccharomyces cerevisiae, has a number of endogenous yeast prions-epigenet...

Poly-L-histidine inhibits prion propagation in a prion-infected cell line.

Transmissible spongiform encephalopathies (TSEs) are a group of lethal neurodegenerative diseases involving the structural conversion of cellular prion protein (PrP) into the pathogenic isoform (PrP) ...

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity.

Antibodies to the prion protein, PrP, represent a promising therapeutic approach against prion diseases but the neurotoxicity of certain anti-PrP antibodies has caused concern. Here we describe scPOM-...

How graphene affects the misfolding of human prion protein: A combined experimental and molecular dynamics simulation study.

As the broad application of graphene in the biomedical field, it is urgent and important to evaluate how the graphene affects the structure and function of the proteins in our body, especially the amy...

Clinical Trials [758 Associated Clinical Trials listed on BioPortfolio]

PRION-1: Quinacrine for Human Prion Disease

PRION-1 aims to assess the activity and safety of Quinacrine (Mepacrine hydrochloride) in human prion disease. It also aims to establish an appropriate framework for the clinical assessmen...

Enhanced CJD Surveillance in the Older Population

The purpose of this study to investigate if cases of Creutzfeldt-Jakob Disease (CJD) and other forms of prion disease are being missed in older adults living within Lothian.

Translating Evidence Based Developmental Screening Into Pediatric Primary Care

The purpose of this study is to examine the feasibility, acceptability and effectiveness of implementing the AAP's recommendation that clinicians provide developmental surveillance at all ...

The Role of the Coagulation Pathway at the Synapse in Prion Diseases

The study hypothesis is that that the deleterious effect of prions on the brain may be mediated (at least partially) by activation of serine proteases involved in the coagulation system. I...

Developmental Dyslexia and Functional Maturation of Auditory Cortex

Developmental dyslexia is a frequent learning disability. The aim of this study is to compare auditory evoked cortical responses to syllables and tones in developmental dyslexia and contro...

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We have published hundreds of Prion Developmental Laboratories news stories on BioPortfolio along with dozens of Prion Developmental Laboratories Clinical Trials and PubMed Articles about Prion Developmental Laboratories for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Prion Developmental Laboratories Companies in our database. You can also find out about relevant Prion Developmental Laboratories Drugs and Medications on this site too.

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