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Human Protein Atlas (HPA) Company Profile

06:46 EDT 21st June 2018 | BioPortfolio

The protein atlas contains histological images from sections of human tissue. These images are equivalent to what is seen in a microscope when examining sections of tissue on glass slides. Each antibody in the database has been used for immunohistochemical staining of both normal and cancer tissue. The immunohistochemical protocols used result in a brown-black staining, localized where an antibody has bound to its corresponding antigen. The tissue section is furthermore histochemically stained with hematoxylin to enable visualization of microscopical features. Hematoxylin staining is unspecific and results in a blue coloring of both cells and extracellular material.Tissue microarrays have been used to enable immunohistochemical staining of a large number and variety of normal and cancerous tissues. The design of used tissue microarrays include samples of 48 different normal tissue types and 20 different types of cancer. For each antibody, protein expression patterns in normal tissue can be viewed as triplicates from 144 different individuals and in cancer tissue viewed as duplicates from 216 different patients. Normally, a fraction of the 576 images are missing for each antibody due to technical issues. Samples of normal and cancer tissue have been collected from anonymized paraffin embedded material of surgical specimens, in accordance with approval from the local ethics committee

Location

Stockholm
Uppsala
Sweden

Contact

Email: contact@hpr.se


News Articles [1449 Associated News Articles listed on BioPortfolio]

Reddit AMA: The Human Cell Atlas

On Thursday, April 26, the Human Cell Atlas Organizing Committee and Reddit Science will discuss "The Human Cell Atlas". Cells are the most fundamental unit of life, yet we know surprisingly little a...

Scientists generate an atlas of the human genome using stem cells

(The Hebrew University of Jerusalem) Scientists from the Hebrew University of Jerusalem have generated an atlas of the human genome that illuminates the roles our genes play in health and disease. Th...

Blod och hjärna - två nya atlasprojekt på väg

Under veckans symposium om precision medicine i Stockholm, passar Scilifelab på att redogöra för vad som händer inom området i Sverige. Linn Fagerberg från protein-atlas-projektet avslöjar fler...

Blod och hjärna - nya atlasprojekt på väg

Under veckans symposium om precision medicine i Stockholm, passar Scilifelab på att redogöra för vad som händer inom området i Sverige. Linn Fagerberg från protein-atlas-projektet avslöjar fler...

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

Building better tiny kidneys to test drugs and help people avoid dialysis

(University of Southern California) A free online kidney atlas built by USC researchers empowers stem cell scientists everywhere to generate more human-like tiny kidneys for testing new drugs and crea...

Researchers map out the atlas of gene regulators in human cardiac cells for the first time

Information for building cells is stored in our genetic material, otherwise known as DNA. It is here that you find all the blueprints for the more than 20,000 different proteins in the human body. Eac...

ATLAS FINANCIAL SHAREHOLDER ALERT: CLAIMSFILER Reminds Investors with Losses in Excess of ...

Atlas investors should visit us at https://www.claimsfiler.com/cases/view-atlas-financial-holdings-inc-securities-litigationor call to speak to our claim center toll-free at (844) 367-9658.   Abou...

PubMed Articles [5051 Associated PubMed Articles listed on BioPortfolio]

The Human Cell Atlas: Technical approaches and challenges.

The Human Cell Atlas is a large, international consortium that aims to identify and describe every cell type in the human body. The comprehensive cellular maps that arise from this ambitious effort ha...

Mapping human development at single-cell resolution.

Human development is regulated by spatiotemporally restricted molecular programmes and is pertinent to many areas of basic biology and human medicine, such as stem cell biology, reproductive medicine ...

CASTp 3.0: computed atlas of surface topography of proteins.

Geometric and topological properties of protein structures, including surface pockets, interior cavities and cross channels, are of fundamental importance for proteins to carry out their functions. Co...

The Cancer Genome Atlas: Creating Lasting Value beyond Its Data.

The Cancer Genome Atlas (TCGA) team now presents the Pan-Cancer Atlas, investigating different aspects of cancer biology by analyzing the data generated during the 10+ years of the TCGA project.

Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas.

Group A Streptococcus (GAS) remains one of the top 10 deadliest human pathogens worldwide despite its sensitivity to penicillin. Although the most common GAS infection is pharyngitis (strep throat), i...

Clinical Trials [4439 Associated Clinical Trials listed on BioPortfolio]

European Post-Market Study for Medial Knee Osteoarthritis Treated With the Atlas Knee System for Load Reduction

The objective of this study is to collect post market data on safety and performance of the Atlas Knee System in patients with osteoarthritis (OA) of the medial knee compartment through a ...

Developing an Atlas to Teach Nurses to Clean Micro-instruments Used in Cataract Surgery: Effect on Patient Safety

Aims and objectives The purpose of this study was to develop an atlas to explore the effect of micro-instrument cleaning on the safety of cataract surgery. Background Cataract surgery saf...

Noninferiority Trial of Liquid Human Milk Fortifier (HMF) Hydrolyzed Protein Versus Liquid HMF With Supplemental Liquid Protein

Breast milk is readily accepted as the ideal source of nutrition for almost all infants, including premature or very low birth weight infants. However, these high-risk infants require the ...

Atlas Predicted DBS Settings in Essential Tremor

Programming Deep Brain Stimulation for the treatment of Essential Tremor can be a time intensive process. Using an atlas created using functional tremor responses in the operating room to ...

Neuroform Atlas Stent for Intracranial Aneurysm Treatment

The primary objective of this study is to demonstrate effectiveness and safety of the NeuroForm Atlas stent system for use in patients requiring stent assisted intracranial aneurysm treatm...

Companies [1692 Associated Companies listed on BioPortfolio]

Confirmant Limited

Formed in June 2001, Confirmant is a joint venture between OGS and Marconi. It was conceived to develop, commercialise and market the output from OGS high throughput proteomics process.The first produ...

Human Protein Atlas (HPA)

The protein atlas contains histological images from sections of human tissue. These images are equivalent to what is seen in a microscope when examining sections of tissue on glass slides. Each antibo...

Atlas Medical Software

Atlas Medical delivers cost-effective outreach solutions for the healthcare enterprise that include integrated CPOE for Laboratory, Radiology, ePrescribing and other disciplines, ...

Atlas Development Corporation

ATLAS Medical delivers cost-effective outreach and clinical solutions for the healthcare enterprise that include integrated CPOE for Laboratory, Radiology, ePrescribing and ...

Padlock Therapeutics

Padlock Therapeutics is a private, Cambridge, Massachusetts-based biotechnology company dedicated to creating new medicines to treat destructive autoimmune diseases. The company l...

More Information about "Human Protein Atlas (HPA)" on BioPortfolio

We have published hundreds of Human Protein Atlas (HPA) news stories on BioPortfolio along with dozens of Human Protein Atlas (HPA) Clinical Trials and PubMed Articles about Human Protein Atlas (HPA) for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Human Protein Atlas (HPA) Companies in our database. You can also find out about relevant Human Protein Atlas (HPA) Drugs and Medications on this site too.

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