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Human Protein Atlas (HPA) Company Profile

13:26 EDT 18th September 2018 | BioPortfolio

The protein atlas contains histological images from sections of human tissue. These images are equivalent to what is seen in a microscope when examining sections of tissue on glass slides. Each antibody in the database has been used for immunohistochemical staining of both normal and cancer tissue. The immunohistochemical protocols used result in a brown-black staining, localized where an antibody has bound to its corresponding antigen. The tissue section is furthermore histochemically stained with hematoxylin to enable visualization of microscopical features. Hematoxylin staining is unspecific and results in a blue coloring of both cells and extracellular material.Tissue microarrays have been used to enable immunohistochemical staining of a large number and variety of normal and cancerous tissues. The design of used tissue microarrays include samples of 48 different normal tissue types and 20 different types of cancer. For each antibody, protein expression patterns in normal tissue can be viewed as triplicates from 144 different individuals and in cancer tissue viewed as duplicates from 216 different patients. Normally, a fraction of the 576 images are missing for each antibody due to technical issues. Samples of normal and cancer tissue have been collected from anonymized paraffin embedded material of surgical specimens, in accordance with approval from the local ethics committee

Location

Stockholm
Uppsala
Sweden

Contact

Email: contact@hpr.se


News Articles [1458 Associated News Articles listed on BioPortfolio]

Reddit AMA: The Human Cell Atlas

On Thursday, April 26, the Human Cell Atlas Organizing Committee and Reddit Science will discuss "The Human Cell Atlas". Cells are the most fundamental unit of life, yet we know surprisingly little a...

Experimental and computational framework for a dynamic protein atlas of human cell division

Scientists generate an atlas of the human genome using stem cells

(The Hebrew University of Jerusalem) Scientists from the Hebrew University of Jerusalem have generated an atlas of the human genome that illuminates the roles our genes play in health and disease. Th...

Blod och hjärna - två nya atlasprojekt på väg

Under veckans symposium om precision medicine i Stockholm, passar Scilifelab på att redogöra för vad som händer inom området i Sverige. Linn Fagerberg från protein-atlas-projektet avslöjar fler...

Blod och hjärna - nya atlasprojekt på väg

Under veckans symposium om precision medicine i Stockholm, passar Scilifelab på att redogöra för vad som händer inom området i Sverige. Linn Fagerberg från protein-atlas-projektet avslöjar fler...

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

Ambitious ‘Human Cell Atlas’ Aims to Catalog Every Type of Cell in the Body

(NPR) – For the last two years Regev, a professor of biology at MIT, has been co-leading a massive international effort to get that answer. Called the Human Cell Atlas Consortium, the effort aim...

ATLAS FINANCIAL SHAREHOLDER ALERT: CLAIMSFILER Reminds Investors with Losses in Excess of ...

Atlas investors should visit us at https://www.claimsfiler.com/cases/view-atlas-financial-holdings-inc-securities-litigationor call to speak to our claim center toll-free at (844) 367-9658.   Abou...

PubMed Articles [5036 Associated PubMed Articles listed on BioPortfolio]

Mapping human development at single-cell resolution.

Human development is regulated by spatiotemporally restricted molecular programmes and is pertinent to many areas of basic biology and human medicine, such as stem cell biology, reproductive medicine ...

Book Review: The Breastfeeding Atlas Wilson-Clay B. Hoover K. ( 2017 ). The Breastfeeding Atlas ( 6th ed.) . Manchaca, TX : LactNews Press . 206 pp. $80.00 (spiral bound paperback), ISBN-13: 978-0-9672758-4-0 .

From the Human Cell Atlas to dynamic immune maps in human disease.

A probabilistic atlas of the human thalamic nuclei combining ex vivo MRI and histology.

The human thalamus is a brain structure that comprises numerous, highly specific nuclei. Since these nuclei are known to have different functions and to be connected to different areas of the cerebral...

Can atlas-based auto-segmentation ever be perfect? Insights from Extreme Value Theory.

Atlas-based segmentation is used in radiotherapy planning to accelerate the delineation of organs at risk (OARs). Atlas selection has been proposed to improve the performance of segmentation, assuming...

Clinical Trials [4676 Associated Clinical Trials listed on BioPortfolio]

Atlas of Human Cognition by SEEG (MAPCOG-SEEG)

The main objective of MAPCOG_SEEG is to create a database including brain recordings of cognition performed in clinical routine in patients during the pre-surgical SEEG assessment. This ai...

European Post-Market Study for Medial Knee Osteoarthritis Treated With the Atlas Knee System for Load Reduction

The objective of this study is to collect post market data on safety and performance of the Atlas Knee System in patients with osteoarthritis (OA) of the medial knee compartment through a ...

Developing an Atlas to Teach Nurses to Clean Micro-instruments Used in Cataract Surgery: Effect on Patient Safety

Aims and objectives The purpose of this study was to develop an atlas to explore the effect of micro-instrument cleaning on the safety of cataract surgery. Background Cataract surgery saf...

Noninferiority Trial of Liquid Human Milk Fortifier (HMF) Hydrolyzed Protein Versus Liquid HMF With Supplemental Liquid Protein

Breast milk is readily accepted as the ideal source of nutrition for almost all infants, including premature or very low birth weight infants. However, these high-risk infants require the ...

Atlas Predicted DBS Settings in Essential Tremor

Programming Deep Brain Stimulation for the treatment of Essential Tremor can be a time intensive process. Using an atlas created using functional tremor responses in the operating room to ...

Companies [1710 Associated Companies listed on BioPortfolio]

Confirmant Limited

Formed in June 2001, Confirmant is a joint venture between OGS and Marconi. It was conceived to develop, commercialise and market the output from OGS high throughput proteomics process.The first produ...

Human Protein Atlas (HPA)

The protein atlas contains histological images from sections of human tissue. These images are equivalent to what is seen in a microscope when examining sections of tissue on glass slides. Each antibo...

Atlas Medical Software

Atlas Medical delivers cost-effective outreach solutions for the healthcare enterprise that include integrated CPOE for Laboratory, Radiology, ePrescribing and other disciplines, ...

Atlas Development Corporation

ATLAS Medical delivers cost-effective outreach and clinical solutions for the healthcare enterprise that include integrated CPOE for Laboratory, Radiology, ePrescribing and ...

Padlock Therapeutics

Padlock Therapeutics is a private, Cambridge, Massachusetts-based biotechnology company dedicated to creating new medicines to treat destructive autoimmune diseases. The company l...

More Information about "Human Protein Atlas (HPA)" on BioPortfolio

We have published hundreds of Human Protein Atlas (HPA) news stories on BioPortfolio along with dozens of Human Protein Atlas (HPA) Clinical Trials and PubMed Articles about Human Protein Atlas (HPA) for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Human Protein Atlas (HPA) Companies in our database. You can also find out about relevant Human Protein Atlas (HPA) Drugs and Medications on this site too.

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