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Protein Structure Factory Company Profile

04:48 EDT 21st June 2018 | BioPortfolio

The term "Protein Structure Factory" stands for a common initiative of structural biologists from the Berlin area and the German Human Genome Project (DHGP). The Protein Structure Factory represents an integrative approach to the high-throughput analysis of three-dimensional protein structures.We have set out to establish an analytical infrastructure to characterize human proteins whose cDNA sequences are available at the Resource Center of the DHGP in Berlin. Target proteins are selected on grounds of predicted novelty of the structure as well as medical or biological relevance. We combine sequence analysis with bioinformatics, automated gene expression and protein purification, determination of a biophysical fingerprint and finally the three-dimensional protein structure analysis by either NMR spectroscopy or X-ray diffraction techniques. The crystal structure analysis will use the synchrotron radiation of the storage ring BESSY in Berlin

Location

Robert-Roessle-Str. 10
Berlin
D-13092
Germany

Contact

Phone: 49 (0)30 9406 2987
Fax: 49 (0)30 9406 2925
Email: psf@fu-berlin.de


News Articles [945 Associated News Articles listed on BioPortfolio]

One point for crowdsourcing: Gamers solve protein structure of AIDS-like protein

A small group of enthusiastic gamers on a site called Foldit recently solved the structure of a protein found in an AIDS-like monkey virus. The structure had stumped scientists for over a decade; the ...

Natural GMOs Part 272. Cells Talk in a Language That Looks Like Viruses | Quanta Magazine

Raw Materials for EvolutionWhen the neuroscientist Jason Shepherd and his postdoc Elissa Pastuzyn at the University of Utah began trying to decode the detailed structure of the Arc protein, they knew ...

Structure of protein pair provides blueprint for future drugs

(Walter and Eliza Hall Institute) Walter and Eliza Hall Institute researchers have visualized for the first time how the protein SOCS1 'switches off' cell signalling to dampen immune responses and blo...

A chink in bacteria's armor

Scientists have untangled the structure of a recently discovered bacterial wall-building protein, found in nearly all bacteria. The discovery unveils potential weak spots in the protein's molecular ma...

Decoding the structure of huntingtin

(Max-Planck-Gesellschaft) Determining the three dimensional structure of the protein could help to develop new treatments of Huntington's disease.

A protein that self-replicates

(ETH Zurich) ETH scientists have been able to prove that a protein structure widespread in nature -- the amyloid -- is theoretically capable of multiplying itself. This makes it a potential predecesso...

GE creates ready-to-run factory for viral vector drugs

GE Healthcare has created a ‘factory-in-a-box’ facility for the production of viral vector-based drugs, including viral vector vaccines, oncolytic viruses,...Read More... The post GE creat...

Artificial leaf as mini-factory for medicine

(Eindhoven University of Technology) Using sunlight for sustainable and cheap production of, for example, medicines. The 'mini-factory' in the form of a leaf that chemical engineers from Eindhoven Uni...

PubMed Articles [3638 Associated PubMed Articles listed on BioPortfolio]

mTM-align: an algorithm for fast and accurate multiple protein structure alignment.

As protein structure is more conserved than sequence during evolution, multiple structure alignment can be more informative than multiple sequence alignment, especially for distantly related proteins....

The impact of ERAD on recombinant protein secretion in Pichia pastoris (syn Komagataella spp.).

The yeast Pichia pastoris (syn. Komagataella spp.) is a popular cell factory for recombinant protein production. Yeasts in general provide a good starting point for cell factory engineering. They are ...

Changes in bacterial community structure and antibiotic resistance genes in soil in the vicinity of a pharmaceutical factory.

China is the largest global producer of antibiotics. With the demand for antibiotics increasing every year, it is necessary to assess potential environmental risks and the spread of antibiotic resista...

Protein super-secondary structure and quaternary structure topology: theoretical description and application.

This review comprises theoretical approaches and recent developments to describe the super-secondary and quaternary structure topology of a protein in a mathematically unique way. Based on the advance...

The effects of dusts of bartin cement factory on Taurus Cedar (Cedru libani A Rich.) seeds' germination.

The present study effects of pollutant particles from Bartın Cement Factory on development of seeds and leaves of Taurus Cedar (Cedrus libani Rich.) which in plantation area around the factory were e...

Clinical Trials [2622 Associated Clinical Trials listed on BioPortfolio]

Studying Exposure to Trichloroethylene in Factory Workers in Guangdong Province, China

RATIONALE: Exposure to trichloroethylene in the workplace may increase the risk of damaging white blood cells. Learning about the long-term effects of trichloroethylene exposure in factory...

Meat and Whey Protein Supplementation in Athletes

The aim of this project is to investigate the potential benefits of combining a new protein meat hydrolysates extract with a regular resistance training programme on (a) body composition (...

Beef Protein Supplementation in Endurance Athletes

The aim of this project is to investigate the potential benefits of combining a new protein beef hydrolysates extract with a regular endurance training programme on (a) body composition (b...

Improving Anemia Status of Female Garment Workers in Bangladesh: An Evaluation of Pilot Intervention in Four Factories

The current study is aimed at evaluating nutrition interventions to be implemented for improving health and nutritional status of female garments workers in 4 selected garment factories in...

Meat and Whey Protein Supplementation in Endurance Athletes

The aim of this project is to investigate the potential benefits of combining a new protein meat hydrolysates extract with a regular endurance training programme on (a) body composition (b...

Companies [1128 Associated Companies listed on BioPortfolio]

Protein Structure Factory

The term "Protein Structure Factory" stands for a common initiative of structural biologists from the Berlin area and the German Human Genome Project (DHGP). The Protein Structure Factory represents a...

Protein Structure Factory Bio tech A G

Since 1996 we helped shape a new science: Structural Genomics. By 1998, theProtein Structure Factory started to set up a massive infrastructure with robots,synchrotron beamlines and high-field NMR fac...

PSF biotech AG

PSF biotech (the protein structure factory™) combines state-of-the-art expertise and resources for structure supported drug discovery. Based on our high throughput crystallography platform we offer ...

Biodesy, Inc.

Biodesy is developing the first products and systems to rapidly and inexpensively measure both protein structure and function in real time, with applications including drug discov...

GeneFormatics Incorporated

GeneFormatics is founded on leading-edge technology developed by a world-class scientific team. These scientists have developed ground-breaking methods for the analysis and prediction of protein struc...

More Information about "Protein Structure Factory" on BioPortfolio

We have published hundreds of Protein Structure Factory news stories on BioPortfolio along with dozens of Protein Structure Factory Clinical Trials and PubMed Articles about Protein Structure Factory for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Protein Structure Factory Companies in our database. You can also find out about relevant Protein Structure Factory Drugs and Medications on this site too.

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