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Protein Structure Factory Company Profile

14:17 EST 9th December 2018 | BioPortfolio

The term "Protein Structure Factory" stands for a common initiative of structural biologists from the Berlin area and the German Human Genome Project (DHGP). The Protein Structure Factory represents an integrative approach to the high-throughput analysis of three-dimensional protein structures.We have set out to establish an analytical infrastructure to characterize human proteins whose cDNA sequences are available at the Resource Center of the DHGP in Berlin. Target proteins are selected on grounds of predicted novelty of the structure as well as medical or biological relevance. We combine sequence analysis with bioinformatics, automated gene expression and protein purification, determination of a biophysical fingerprint and finally the three-dimensional protein structure analysis by either NMR spectroscopy or X-ray diffraction techniques. The crystal structure analysis will use the synchrotron radiation of the storage ring BESSY in Berlin

Location

Robert-Roessle-Str. 10
Berlin
D-13092
Germany

Contact

Phone: 49 (0)30 9406 2987
Fax: 49 (0)30 9406 2925
Email: psf@fu-berlin.de


News Articles [924 Associated News Articles listed on BioPortfolio]

One point for crowdsourcing: Gamers solve protein structure of AIDS-like protein

A small group of enthusiastic gamers on a site called Foldit recently solved the structure of a protein found in an AIDS-like monkey virus. The structure had stumped scientists for over a decade; the ...

New insights into the structure of a killer protein

(Ruhr-University Bochum) Researchers at Ruhr-Universität Bochum and the University of Tübingen have gained new insights into the structure of the killer protein Bax. The protein induces programmed c...

Cryo-EM reveals structure of protein responsible for regulating body temperature

Scientists have revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and bipolar disorder.

Structure of Protein Responsible for Body Temperature Revealed

NewsFor the first time, scientists have revealed the atomic-level structure of a protein that may be a promising drug target for Alzheimer's and bipolar disorder.

BeiGene adopts GE ‘turnkey’ factory for anti-PD-1 mAb production

BeiGene will use GE Healthcare Life Sciencesâ âoff-the-shelfâ factory to manufacture monoclonal antibodies in Guangdong Province, China.

Structure and key features of critical immune-surveillance protein in humans

Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections. The identification of two human-specific va...

Why two? Structure of protein FAT10 analyzed

FAT10 is a small protein with a huge effect. Its attachment to a target protein is a signal for its degradation. FAT10 is a marking system for degradation that seems to be inefficient. In contrast to ...

The Latest on Protein Folding

The results of the biannual CASP (Critical Assessment of Structure Prediction) effort have been released. This is a widely-watched competition between different groups (and different programs, methods...

PubMed Articles [3590 Associated PubMed Articles listed on BioPortfolio]

POPPeT: a New Method to Predict the Protection Factor of Backbone Amide Hydrogens.

Hydrogen exchange (HX) has become an important tool to monitor protein structure and dynamics. The interpretation of HX data with respect to protein structure requires understanding of the factors tha...

mTM-align: a server for fast protein structure database search and multiple protein structure alignment.

With the rapid increase of the number of protein structures in the Protein Data Bank, it becomes urgent to develop algorithms for efficient protein structure comparisons. In this article, we present t...

MDockPeP: An ab-initio protein-peptide docking server.

Protein-peptide interactions play a crucial role in a variety of cellular processes. The protein-peptide complex structure is a key to understand the mechanisms underlying protein-peptide interactions...

Topology independent structural matching discovers novel templates for protein interfaces.

Protein-protein interactions (PPI) are essential for the function of the cellular machinery. The rapid growth of protein-protein complexes with known 3D structures offers a unique opportunity to study...

De novo protein structure prediction using ultra-fast molecular dynamics simulation.

Modern genomics sequencing techniques have provided a massive amount of protein sequences, but experimental endeavor in determining protein structures is largely lagging far behind the vast and unexpl...

Clinical Trials [2928 Associated Clinical Trials listed on BioPortfolio]

Studying Exposure to Trichloroethylene in Factory Workers in Guangdong Province, China

RATIONALE: Exposure to trichloroethylene in the workplace may increase the risk of damaging white blood cells. Learning about the long-term effects of trichloroethylene exposure in factory...

Meat and Whey Protein Supplementation in Athletes

The aim of this project is to investigate the potential benefits of combining a new protein meat hydrolysates extract with a regular resistance training programme on (a) body composition (...

Beef Protein Supplementation in Endurance Athletes

The aim of this project is to investigate the potential benefits of combining a new protein beef hydrolysates extract with a regular endurance training programme on (a) body composition (b...

Improving Anemia Status of Female Garment Workers in Bangladesh: An Evaluation of Pilot Intervention in Four Factories

The current study is aimed at evaluating nutrition interventions to be implemented for improving health and nutritional status of female garments workers in 4 selected garment factories in...

Meat and Whey Protein Supplementation in Endurance Athletes

The aim of this project is to investigate the potential benefits of combining a new protein meat hydrolysates extract with a regular endurance training programme on (a) body composition (b...

Companies [1150 Associated Companies listed on BioPortfolio]

Protein Structure Factory

The term "Protein Structure Factory" stands for a common initiative of structural biologists from the Berlin area and the German Human Genome Project (DHGP). The Protein Structure Factory represents a...

Protein Structure Factory Bio tech A G

Since 1996 we helped shape a new science: Structural Genomics. By 1998, theProtein Structure Factory started to set up a massive infrastructure with robots,synchrotron beamlines and high-field NMR fac...

PSF biotech AG

PSF biotech (the protein structure factory™) combines state-of-the-art expertise and resources for structure supported drug discovery. Based on our high throughput crystallography platform we offer ...

Biodesy, Inc.

Biodesy is developing the first products and systems to rapidly and inexpensively measure both protein structure and function in real time, with applications including drug discov...

GeneFormatics Incorporated

GeneFormatics is founded on leading-edge technology developed by a world-class scientific team. These scientists have developed ground-breaking methods for the analysis and prediction of protein struc...

More Information about "Protein Structure Factory" on BioPortfolio

We have published hundreds of Protein Structure Factory news stories on BioPortfolio along with dozens of Protein Structure Factory Clinical Trials and PubMed Articles about Protein Structure Factory for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Protein Structure Factory Companies in our database. You can also find out about relevant Protein Structure Factory Drugs and Medications on this site too.

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