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(Children's National Health System) The type of hypoxia that occurs with preterm birth is associated with locomotor miscoordination and long-term cerebellar learning deficits but can be partially alle...
Posttranslational modifications of tubulin are emerging regulators of microtubule functions. We have shown earlier that upregulated polyglutamylation is linked to rapid degeneration of Purkinje cells ...
A set of glutamylases and deglutamylases controls levels of tubulin polyglutamylation, a prominent post-translational modification of neuronal microtubules. Defective tubulin polyglutamylation was fir...
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ARSACS is an early-onset neurodegenerative human disease characterized in part by ataxia and Purkinje cell loss in anterior cerebellar lobules. A knock-out mouse model has been developed that recapitu...
There has always been an appreciation of the role of Purkinje fibers in the fast conduction of the normal cardiac impulse. Here, we briefly update our knowledge of this important set of cardiac cells....
The brain has traditionally been considered to be a target site of peripheral steroid hormones.On the other hand, extensive studies over the past thirty years have demonstrated that the brain is a sit...
Spinocerebellar ataxia type 14 (SCA14) is a dominantly inherited neurodegenerative disease caused by diverse mutations in the Protein Kinase C gamma (PKCγ) gene which is one of the crucial signaling ...
We reviewed the anatomical characteristics of the conduction system in the ventricles of human and ungulate hearts and then raised some questions to be answered by clinical and anatomical studies in t...
The hereditary cerebellar ataxias include diverse neurodegenerative disorders. Hereditary ataxias can be divided into autosomal dominant ataxias (ADCAs), autosomal recessive ataxias (ARCAs...
A cross-border merger in 2005 brought together two companies known for delivering innovative clinical solutions to physician offices and hospitals in the United States and Canada. With over 250 employ...
QTest Labs provides economical and rapid testing between drug discovery and preclinical trials . With a 2 week turn-around time and before conventional elaborate and expensive preclinical trials. QTes...
To provideNon-Clinical drug safety testing and discovery services that accelerate drug development by:Leveraging our extensive experience in evaluating drug-induced effects on ion channels, purkinje f...
We have published hundreds of Purkinje news stories on BioPortfolio along with dozens of Purkinje Clinical Trials and PubMed Articles about Purkinje for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Purkinje Companies in our database. You can also find out about relevant Purkinje Drugs and Medications on this site too.
Mergers & Acquisitions
Commercial and market reports on mergers and acquisitions in the biotechnology, pharmaceutical, medical device and life-science industries. Mergers and acquisitions (abbreviated M&A;) is an aspect of corporate strategy, corporate finance and manageme...
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...