TiGenix NV Company Profile

09:32 EDT 26th September 2018 | BioPortfolio

TiGenix NV (NYSE Euronext: TIG) is a leading European cell therapy company with a commercial product and an advanced clinical stage pipeline of adult stem cell programs.
The company’s lead product, ChondroCelect®, for cartilage repair in the knee, is the only approved cell-based product in Europe, and is currently being launched in different European countries.
TiGenix’s stem cell programs are based on a validated platform of allogeneic expanded adipose-derived stem cells (eASCs) targeting autoimmune and inflammatory diseases. Built on solid pre-clinical and CMC packages, they are being developed in close consultation with the European Medicines Agency.  The company has initiated a Phase III clinical trial in complex perianal fistulas in patients with Crohn’s disease, is conducting a Phase IIa trial in rheumatoid arthritis, and successfully concluded a Phase I trial to investigate the potential of intra-lymphatic administration of eASCs for autoimmune disorders.
TiGenix is based out of Leuven (Belgium), and has operations in Madrid (Spain), and Sittard-Geleen (the Netherlands).


Haasrode Researchpark 1724
Romeinse straat 12 bus 2


Phone: +32 (0) 16 39 60 60
Fax: +32 (0) 16 39 79 70

News Articles [50 Associated News Articles listed on BioPortfolio]

Takeda and TiGenix Announce Results of First Acceptance Period for the Voluntary and Conditional Public Takeover Bid of TiGenix

Takeda Pharmaceutical (TSE:4502) and TiGenix (Euronext Brussels and Nasdaq:TIG) today announced the results of the first acceptance period of Takeda’s previously announced tender offer in cash f...

Takeda closes TiGenix acquisition for about $608m

Takeda Pharmaceutical has completed its purchase of all outstanding ordinary shares of Belgium-based TiGenix for approximately $608.84m (€520m), representing €1.78...Read More... The post Takeda c...

TiGenix, Takeda's allogeneic stem cell therapy wins EU nod

The European Commission approved TiGenix and Takeda Pharmaceutical's Alofisel, or darvadstrocel, as a treatment for adult pat -More- 

Takeda finalises buyout of TiGenix

Japanese pharma giant Takeda has completed its buyout of TiGenix. Takeda’s main R&D focus is in oncology, gastroenterology and neuroscience therapeutic areas, and vaccines. The company employs ...

Tigenix: Maria Pascual. ChondroCelect®, Europe's first and only approved cell-based product

In this episode of PharmaTelevision News Review, filmed at BioPartnering Future Europe in Brussels, Fintan Walton talks to Maria Pascual, VP of Regulatory Affairs and Corporate QA at Tigenix

EU Yes For TiGenix Marks Tenth ATMP Approval in Ten Years

TiGenix says its treatment for complex perianal fistulae in Crohn’s disease is the first allogeneic stem cell to be approved...   

TiGenix and Takeda Get EU Nod for Crohn’s Therapy

TiGenix and Takeda’s Alofisel has won clearance from the European Commission, making it the first allogeneic stem cell therapy to be approved for use in Europe. Alofisel, previously known as ...

Takeda Secures TiGenix But Investor Shire Concerns Bubble Up

Takeda has closed its $630m acquisition of European regenerative medicine company TiGenix following a successful bid process, but is facing...  

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Companies [2 Associated Companies listed on BioPortfolio]

TiGenix NV

TiGenix NV (NYSE Euronext: TIG) is a leading European cell therapy company with a commercial product and an advanced clinical stage pipeline of adult stem cell programs. The company’s lead pr...

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Autoimmune Disorders
Autoimmune disorders are conditions that occurs when the immune system mistakenly attacks and destroys healthy body tissue. There are more than 80 different types of autoimmune disorders. Normally the immune system's white blood cells help protect ...

Clincial Trials
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...

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