Target Discovery, Inc. Company Profile

07:46 EST 10th December 2018 | BioPortfolio

Target Discovery discovers, validates, and utilizes protein isoforms to improve clinical diagnosis and management of disease. A growing body of scientific literature shows that protein isoforms correlate more precisely with disease state and patient-specific treatment response than current clinical biomarkers. Most protein isoforms (90%) are made by the body after the protein is produced (post-translational modifications). Such protein modifications remain largely inaccessible to current immunodiagnostic and nucleic acid clinical assays. Target Discovery's Isonostic™ products are designed to make this isoform biomarker information accessible to clinicians.


4030 Fabian Way
Palo Alto
United States of America


Phone: 1.650.812.8100
Fax: 1.650.812.8130

News Articles [469 Associated News Articles listed on BioPortfolio]

Most downloaded review Q1 2009: Target discovery from data mining approaches

The most downloaded review article from Drug Discovery Today from the first quarter of 2009 deals with the topic of target discovery from the informatics perspective. It would be difficult to overstat...

Sygnature Discovery Announces Multi-Target Drug Discovery Deal with Sitryx Therapeutics

Sygnature Discovery, a leading independent integrated drug discovery and pre-clinical services company, has today announced a multi-target, integrated drug discovery collaboration with Sitryx Therapeu...

Pfizer and CYTOO develop DMD target discovery platform

The research collaboration will aim to modify CYTOO s existing MyoScreen platform to enable its potential use as a Duchenne muscular dystrophy target discovery platform

Researchers reveal complexity of NMDA receptor drug discovery target

Know your target. Especially if your target is coming into focus for treating diseases such as schizophrenia and treatment-resistant depression.

CYTOO and Pfizer join forces for Duchenne Muscular Dystrophy target discovery platform

Preclinical stage drug discovery company, CYTOO, and biopharmaceutical company, Pfizer, have announced a research collaboration with the aim of developing a target discovery platform for Duchenne Musc...

#jobs #lifescience Sr Scientist Molecular Genomics Early Target Discovery

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Sr Scientist Molecular Genomics Early Target Discovery .CA-San Diego, By clic...

Aclaris Therapeutics to Highlight Drug Discovery Targeting the Human Kinome at 16th Annual Discovery on Target Meeting

WAYNE, Pa., Sept. 17, 2018 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ:ACRS) announced that its subsidiary, Confluence Discovery Technologies, Inc., will present two posters at Cambridge...

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

PubMed Articles [1407 Associated PubMed Articles listed on BioPortfolio]

The power of combining phenotypic and target-focused drug discovery.

A fierce dispute has arisen between the supporters of phenotypic and target-focused screening regarding which path grants the higher probability of successful drug development. A chance to reconcile t...

Importance of target-mediated drug disposition for small molecules.

Target concentration is typically not considered in drug discovery. However, if targets are expressed at relatively high concentrations and compounds have high affinity, such that most of the drug is ...

Microfluidics contribution to pharmaceutical sciences: From drug discovery to post marketing product management.

Drug discovery and development is a long-lasting process in which many challenges have to be addressed at every stage, from the discovery of the target biomolecule to the commercialization of the disc...

Decaprenyl-phosphoryl-ribose 2'-epimerase (DprE1): challenging target for antitubercular drug discovery.

Tuberculosis has proved harmful to the entire history of mankind from past several decades. Decaprenyl-phosphoryl-ribose 2'-epimerase (DprE1) is a recent target which was identified in 2009 but unfort...

Computational Toxicology and Drug Discovery.

The use of computational toxicology methods within drug discovery began in the early 2000s with applications such as predicting bacterial mutagenicity and hERG inhibition. The field has been continuou...

Clinical Trials [1936 Associated Clinical Trials listed on BioPortfolio]

Discovery Elbow Multi-Center Prospective Study

The purpose of this prospective clinical trial is to document the performance and clinical outcomes of Biomet Discovery Elbow.

A Clinical Investigation of the Discovery™ Elbow System

The purpose of this study is to perform a five-year, multi-center prospective evaluation of the Discovery™ Elbow System for outcome and durability. Relief of pain and restoration of fun...

Efficacy and Safety of Imatinib in Scleroderma

In vitro studies have shown that imatinib 1mM inhibits strongly the growth of cutaneous fibroblasts. The hypothesis is that imatinib inhibits PDGFR which is known to be a potential target ...

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain

VVZ-149 is a novel analgesic drug candidate that shows a potential analgesic activity inhibiting GlyT2 and 5HT2A simultaneously. These target receptors have been known to play important ro...

Target Validation and Discovery in Idiopathic Bronchiectasis

Bronchiectasis is a long-term lung condition where the airways become abnormally enlarged, leading to a build-up of mucus and inflammation that makes the lungs more susceptible to recurren...

Companies [1657 Associated Companies listed on BioPortfolio]

Chemocept, Inc.

Chemocept is a service company offering the biotechnology industry discovery chemistry support capabilities for use in biomolecular target validation and small molecule drug discovery. We facilitate ...

Target Discovery, Inc.

Target Discovery discovers, validates, and utilizes protein isoforms to improve clinical diagnosis and management of disease. A growing body of scientific literature shows that protein isoforms correl...

Crystax Pharmaceuticals S.L.

Crystax Pharmaceuticals is a leading structure-based drug discovery company providing a unique service to its partners. Crystax has developed an integrated discovery platform, from the identification ...

Target ALS Foundation

Target ALS is an independent, non-profit, and privately funded consortium of researchers from academic and biotech/pharma laboratories entirely focused on finding a treatment for ...

Vividion Therapeutics, Inc.

Conventional drug discovery is target-centric; a compound library is screened using a target-specific assay and high-affinity binding ligands are optimized to develop a drug candi...

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