Resolve Therapeutics, LLC Company Profile

02:22 EST 26th February 2020 | BioPortfolio

Resolve Therapeutics is a privately held biotechnology company based in Seattle that is dedicated to helping patients with lupus through the development of RSLV-125, its novel targeted biologic therapy. RSLV-125 represents a new approach to inhibiting the production of interferon-alpha at a proximal step in the inflammatory cascade. A multitude of evidence points to interferon-alpha as a critical mediator of the inflammation present in lupus patients. Development efforts in this field are greatly enhanced by the recent clinical validation of a biomarker called the “interferon signature” which tracks the activation level of the interferon pathway in lupus patients. The interferon signature provides a valuable pharmacodynamic endpoint which greatly enhances the early clinical evaluation of drugs acting to inhibit the interferon pathway. RSLV-125 is currently in advanced preclinical development, and Resolve expects to begin human clinical studies with this compound in the near future. For more information please visit the Resolve Therapeutics website at

News Articles [886 Associated News Articles listed on BioPortfolio]

Coming in Friday's "The Pink Sheet" DAILY

Takeda Pharmaceuticals has inked an option agreement with Resolve Therapeutics for a pre-clinical lupus drug.

Two Charities to Pay $6 Mln to Resolve U.S. Pharma Kickback Probe

Two charities will pay $6 million to resolve claims they operated as pass-throughs for seven pharmaceutical companies to pay kickbacks to Medicare patients using their high-priced medications, the U.S...

Two charities to pay $6 million to resolve U.S. pharma kickback probe

Two charities will pay $6 million to resolve claims that they operated as pass-throughs for seven pharmaceutical companies to pay kickbacks to Medicare patients using their high-priced medications, th...

Reports: Sackler family offers to relinquish reins of Purdue Pharma to resolve opioid suits

Citing anonymous sources familiar with the matter, news outlets reported that the family would pay $3 billion toward a proposed $10-12 billion settlement to resolve the more than 2,000 lawsuits.

Dyne Therapeutics Announces Support for ReSolve Natural History Study of Patients with Facioscapulohumeral Muscular Dystrophy (FSHD)

Dyne Therapeutics, a biotechnology company pioneering targeted therapies for patients with serious muscle diseases, today announced its support for the ReSolve study, an ongoing natural history study...

Charity to pay $4 million to resolve U.S. pharma kickback probe

A Florida-based charity will pay $4 million to resolve claims that it acted as a conduit for companies including Biogen Inc and Novartis AG to pay kickbacks to Medicare patients using their high-pri...

Statement on the agency’s ongoing efforts to resolve safety issue with ARB medications

The FDA is issuing an update regarding the ongoing efforts to resolve safety issues with ARB medications.

Reckitt to resolve Indivior’s opioid probe with $1.4bn settlement

Reckitt Benckiser has agreed to pay up to $1.4bn to the US Department of Justice (DoJ) and the Federal Trade...Read More... The post Reckitt to resolve Indivior’s opioid probe with $1.4bn settle...

PubMed Articles [550 Associated PubMed Articles listed on BioPortfolio]

Digital Therapeutics: Emerging New Therapy for Neurologic Deficits after Stroke.

Digital therapeutics is an evidence-based intervention using high-quality software, with the sole purpose of treatment. As many healthcare systems are encountering high demands of quality outcomes, th...

Do anatomic changes found in the throwing arm after a season of pitching resolve with off-season rest? A dynamic ultrasound study.

Our hypothesis was that seasonal adaptive changes in the ulnar collateral ligament (UCL), ulnohumeral joint space (UHJS), and glenohumeral internal rotation deficit (GIRD) of the pitching extremity wo...

Measurement of mRNA therapeutics: method development and validation challenges.

The progression of chemically modified mRNA therapeutics through development pipelines is accelerating for many disease indications and the need to assess these analytes is becoming more routine for t...

Dr E. Keith Borden: Inaugural President of the Canadian Association for Population Therapeutics.

Pharmacovigilance 2030: Invited Commentary for the January 2020 "Futures" Edition of Clinical Pharmacology and Therapeutics.

Clinical Trials [380 Associated Clinical Trials listed on BioPortfolio]

Long-term Follow-Up Study Following Treatment With Fate Therapeutics' Engineered Cellular Immunotherapy

The purpose of the study is to assess long-term side effects from subjects who receive a Fate Therapeutics genetically modified NK cell product. Subjects who previously took part in a Fate...

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

RESOLVE II Clinical Evaluation of Safety and Efficacy of S8 Sinus Implant in Chronic Sinusitis Patients

The RESOLVE II Study will assess the safety and efficacy of the steroid-releasing S8 Sinus Implant when used in post-sinus surgery patients who present with recurrent sinus obstruction. Th...

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act...

Companies [1475 Associated Companies listed on BioPortfolio]

Resolve Therapeutics, LLC

Resolve Therapeutics is a privately held biotechnology company based in Seattle that is dedicated to helping patients with lupus through the development of RSLV-125, its novel tar...

ReSolve Research Solutions Inc

ReSolve Research Solutions Inc. is a Site Management Organization (SMO) with corporate offices in Ontario and British Columbia, Canada. We work with a network of qualified and experienced Principal In...


CELLMADE: A CELL-BASED DIAGNOSTICS COMPANY CellMade was established in 2007 by Ronald Bronsaer with support from Sofimac Partners and a group of private investors. In 2009, it established an agr...

Serological Services Limited

provides laboratory testing to resolve paternity, maternity, sibling relationships and other biological family relationships.

Aeris Therapeutics

Aeris Therapeutics is an emerging medical therapeutics company specializing in the development and commercialization of novel treatments for patients with emphysema and other adva...

More Information about "Resolve Therapeutics, LLC" on BioPortfolio

We have published hundreds of Resolve Therapeutics, LLC news stories on BioPortfolio along with dozens of Resolve Therapeutics, LLC Clinical Trials and PubMed Articles about Resolve Therapeutics, LLC for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Resolve Therapeutics, LLC Companies in our database. You can also find out about relevant Resolve Therapeutics, LLC Drugs and Medications on this site too.

Quick Search

Relevant Topics

Biotechnology - Biotech
"using living things to create products or to do tasks for humans" About Biotechnology - Biotech Biotechnology is the practice of using plants, animals and micro-organisms such as bacteria, as well as biological processes - such as the ripen...

Arthritis Fibromyalgia Gout Lupus Rheumatic Rheumatology is the medical specialty concerned with the diagnosis and management of disease involving joints, tendons, muscles, ligaments and associated structures (Oxford Medical Diction...

Lupus is a complex and poorly understood condition that affects many parts of the body and causes symptoms ranging from mild to life-threatening. There are several types of lupus. The main types are: discoid lupus erythematosus drug-induced lu...

Corporate Database Quicklinks

Searches Linking to this Company Record