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Molecular Response LLC Company Profile

20:54 EST 17th January 2019 | BioPortfolio

Molecular Response is a leader in advancing targeted therapeutics through intelligently designed, clinically validated companion diagnostics. Our goal is to reduce risk and cost of therapeutic drug development for our partners by translating clinically relevant molecular response marker data into high-value knowledge while fully integrated into existing pharmaceutical development processes and programs; Our results reduce risk and cost of drug development and allow for the most informed decisions with best chance of success to advance therapeutic programs.


News Articles [916 Associated News Articles listed on BioPortfolio]

Powerful microscope captures first image of nanoscaffold that promotes cell movement

(Sanford Burnham Prebys Medical Discovery Institute) Using one of the most powerful microscopes in the world, scientists from SBP and UNC-Chapel Hill have identified a dense, dynamic and disorganized ...

Molecular links identified between sex and GBM drug response

HMGCLL1 is a predictive biomarker for deep molecular response to imatinib therapy in chronic myeloid leukemia

Keap1–MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa

Publisher Correction: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma

A molecular look at nascent HDL formation

(American Society for Biochemistry and Molecular Biology) Researchers at Boston University pin down a molecular interaction between an apolipoprotein and a lipid transporter that's key to reverse chol...

Neighbor Cell Signals Cause Function Change in Response

A molecular mechanism has been identified that maintains cell identity via an active process, which is mediated by repressive signals...

Molecular switches are not just 'on' or 'off'

(Aarhus University) It is not always easy to see if a switch is on or off! A new study shows that the same can be true of a molecular switch. This knowledge gives a new insight into the molecular swit...

Drugs and Medications [2 Associated Drugs and Medications listed on BioPortfolio]

Nilandron [sanofi-aventis U.S. LLC]

NILANDRON (nilutamide)Tablets

Salsalate [Libertas Pharma, Inc.]

Salsalate Tablets, USP 500 and 750 mgRx Only

PubMed Articles [2527 Associated PubMed Articles listed on BioPortfolio]

Early molecular response ≤1% has strong prognostic impact for CML patients that switch to second-line therapy with BCR-ABL1 ≤10% and no major molecular response.

Dissecting Molecular and Circuit Mechanisms for Inhibition and Delayed Response of ASI Neurons during Nociceptive Stimulus.

The mechanisms by which off-response neurons stay quiescent during stimulation are largely unknown. Here, we dissect underlying molecular and circuit mechanisms for the inhibition of off-response ASI ...

The SOS System: A complex and tightly regulated response to DNA damage.

Genomes of all living organisms are constantly threatened by endogenous and exogenous agents that challenge the chemical integrity of DNA. Most bacteria have evolved a coordinated response to DNA dama...

Comparative analyses of nilotinib versus high-dose imatinib versus sustained standard-dose imatinib in patients with chronic phase chronic myeloid leukemia following suboptimal molecular response to first-line imatinib.

The aim of this study was to investigate the efficacy of nilotinib (NIL) versus high-dose imatinib (IM) versus sustained standard-dose IM for patients with chronic myeloid leukemia (CML) with suboptim...

Molecular signature of response to preoperative radiotherapy in locally advanced breast cancer.

Radiation therapy is an indispensable part of various treatment modalities for breast cancer. Specifically, for non-inflammatory locally advanced breast cancer (LABC) patients, preoperative radiothera...

Clinical Trials [4075 Associated Clinical Trials listed on BioPortfolio]

Study of Molecular Response in Adult Patients on Nilotinib With Philadelphia Chromosome Positive Chronic Myelogenous Leukemia (Ph+ CML) in Chronic Phase and a Suboptimal Molecular Response to Imatinib

This exploratory study will evaluate the change in molecular response in chronic myelogenous leukemia - chronic phase patients with a complete cytogenetic response and have a suboptimal mo...

Imatinib Mesylate and Zoledronic Acid in Patients With Chronic Myeloid Leukaemia in Cytogenetic Response Without Molecular Response

Imatinib mesylate is standard treatment of Chronic myeloid leukaemia, complete cytogenetic response is obtained in most of cases but molecular response concerned only a small part of the p...

Molecular Processes of the Relaxation Response in Older Adults

The purpose of this study is to examine the molecular (nitric oxide) and biochemical (epinephrine, norepinephrine, cortisol and ACTH) parameters that are associated with RR elicitation and...

Retrospective Study Assessing Molecular Features Predicting Response to Cetuximab

The primary objective is to identify molecular features predicting response or resistance to cetuximab

Molecular Response After Concurrent Exercise With Low Glycogen

This is a randomized, counterbalanced crossover design, in which 14 male subjects will complete two experimental trials. Each trial will be separated by a minimum of at least 12 days (rang...

Companies [1309 Associated Companies listed on BioPortfolio]

Molecular Response LLC

Molecular Response is a leader in advancing targeted therapeutics through intelligently designed, clinically validated companion diagnostics. Our goal is to reduce risk and...

Molecular Response

Molecular Response is a leader in advancing targeted therapeutics through intelligently designed, clinically validated companion diagnostics. Our goal is to reduce risk and increa...

Church & Dwight, Co., Inc.

Church and Dwight, Co., Inc., headquartered in Princeton, NJ, distributes First Response Early Result Pregnancy Test and other First Response products, including First Response Gold Digital, First Res...

Gene Network Sciences, Inc.

Gene Network Sciences (http://www.gnsbiotech.com/) is a leader in biosimulation with its ability to derive molecular mechanisms of drugs and diseases directly from molecular profiling and clinical dat...

Nova Molecular Incorporated

Nova Molecular Inc. (NMI) is a Montreal based CNS drug discovery company focused on understanding neuronal degeneration, disease progression, repair mechanisms, therapeutic response and development ba...

More Information about "Molecular Response LLC" on BioPortfolio

We have published hundreds of Molecular Response LLC news stories on BioPortfolio along with dozens of Molecular Response LLC Clinical Trials and PubMed Articles about Molecular Response LLC for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Molecular Response LLC Companies in our database. You can also find out about relevant Molecular Response LLC Drugs and Medications on this site too.

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