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Proteostasis Therapeutics, Inc. Company Profile

06:47 EDT 22nd September 2018 | BioPortfolio

Proteostasis Therapeutics (PTI) is developing novel disease-modifying therapeutics that target the cellular pathways regulating protein folding, trafficking, and clearance. The Proteostasis Network (PN) is comprised of these interconnected cellular pathways and can become imbalanced by the cumulative effects of aging, disease, genetics and environmental factors. The Company is focused on improving outcomes for patients with neurodegenerative and orphan diseases with lead programs in cystic fibrosis and Parkinson’s disease. For more information, please visit www.proteostasis.com.


News Articles [762 Associated News Articles listed on BioPortfolio]

Proteostasis Therapeutics Announces Withdrawal of Equity Offering Due to Market Conditions

About Proteostasis Therapeutics, Inc. Proteostasis Therapeutics, Inc. is a clinical stage biopharmaceutical company developing small molecule therapeutics to treat cystic fibrosis (CF) and other di...

Proteostasis Therapeutics Snags Breakthrough Designation

The U.S. Food and Drug Administration granted Proteostasis Therapeutics' investigational cystic fibrosis add-on therapy the Breakthrough Therapy Designation.

SHAREHOLDER ALERT: Bronstein, Gewirtz Grossman, LLC Announces Investigation of Proteostasis ...

On March 20, 2018, Kerrisdale Capital Management published a report entitled "Proteostasis Therapeutics, Inc.: Hyped-Up Lung Data? Just a Lot of Hot Air."  The Read more...

Active-Investors: Blog Exposure - FDA Granted Fast Track Designation to Proteostasis Therapeutics' Triple Combination Program for Cystic Fibrosis

Stock Monitor: Red Hat Post Earnings Reporting LONDON, UK / ACCESSWIRE / April 6, 2018 / Active-Investors.com has just released a free research report on Proteostasis Therapeutics, Inc. (NASDAQ: P...

Breakthrough status in cystic fibrosis sends Proteostasis up by half

The cystic fibrosis (CF) specialist Proteostasis Therapeutics made gains of 47% in Tuesday morning’s…

FDA breakthrough therapy status granted to Proteostasis' cystic fibrosis drug

The FDA gave therapy status to Proteostasis Therapeutics' PTI-428, which is being developed as a treatment for patients with  -More- 

FDA grants orphan status to Proteostasis' cystic fibrosis drug

Proteostasis Therapeutics' PTI-428, which is being developed as a treatment for patients with cystic fibrosis who have two co -More- 

Scott+Scott Attorneys at Law LLP Announces Investigation into Proteostasis Therapeutics, Inc. (PTI)

Proteostasis is a biopharmaceutical company.  The investigation centers around the Company's cystic-fibrosis drug, PTI-428. On March 20, 2018, Kerrisdale Capital Management LLC published a Read ...

PubMed Articles [485 Associated PubMed Articles listed on BioPortfolio]

Molecular Chaperones: From Proteostasis to Pathogenesis.

Maintaining protein homeostasis (proteostasis) is essential for a functional proteome. A wide range of extrinsic and intrinsic factors perturb proteostasis, causing protein misfolding, misassembly and...

Protein Turnover in Aging and Longevity.

Progressive loss of proteostasis is a hallmark of aging that is marked by declines in various components of proteostasis machinery, including: autophagy, ubiquitin-mediated degradation, protein synthe...

Roles of the nucleotide exchange factor and chaperone Hsp110 in cellular proteostasis and diseases of protein misfolding.

Cellular protein homeostasis (proteostasis) is maintained by a broad network of proteins involved in synthesis, folding, triage, repair and degradation. Chief among these are molecular chaperones and ...

Protein aggregation in cell biology: An aggregomics perspective of health and disease.

Maintaining protein homeostasis (proteostasis) is essential for cellular health and is governed by a network of quality control machinery comprising over 800 genes. When proteostasis becomes imbalance...

Impaired proteostasis during skeletal muscle aging.

Aging is a complex phenomenon that has detrimental effects on tissue homeostasis. The skeletal muscle is one of the earliest tissues to be affected and to manifest age-related changes such as function...

Clinical Trials [155 Associated Clinical Trials listed on BioPortfolio]

Impact of Ibis on Patients With Advanced COPD

The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients wi...

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Assess the effect on coronary atheroma of serial infusions of autologous selectively delipidated HDL/preβ enriched plasma following use of HDL Therapeutics PDS-2™ System

Ontogenesis of the P-Glycoprotein in Human Lymphocytes Influence of HIV and Antiretroviral Therapeutics

The P-glycoprotein (P-gp) is a membranous transporter that modulates the intracellular concentrations of many drugs and plays thus a major role in the efficacy of the therapeutics that act...

A Trial to Find Safe and Active Doses of an Investigational Drug CX-072 for Patients With Solid Tumors or Lymphomas

The purpose of this first-in-human study of CX-072 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-072 administered i...

Identification of Proteostasis-related Biomarkers in Alzheimer´s Dementia

At the time of biomarker-substantiated diagnosis for a given AD patient it remains unclear to what extent the disease will devastate cognitive abilities within the next years. This is not ...

Companies [1256 Associated Companies listed on BioPortfolio]

Proteostasis Therapeutics

Proteostasis Therapeutics is discovering “Proteostasis Regulators” (PRs), small molecule drugs that restore proper protein function to treat neurodegenerative, metabolic...

Proteostasis Therapeutics, Inc.

Proteostasis Therapeutics (PTI) is developing novel disease-modifying therapeutics that target the cellular pathways regulating protein folding, trafficking, and clearance. The Pr...

Proteostasis Therapeutics and Elan Corporation

Proteostasis Therapeutics is developing “Proteostasis Regulators” (PRs), small molecule drugs that restore proper protein function or remove misfolded and aggregated pro...

Aeris Therapeutics

Aeris Therapeutics is an emerging medical therapeutics company specializing in the development and commercialization of novel treatments for patients with emphysema and other adva...

Altair Therapeutics, Inc.

Based in San Diego, Altair Therapeutics, Inc. is a privately-held biopharmaceutical company developing novel therapeutics to treat human respiratory diseases. Altair Therap...

More Information about "Proteostasis Therapeutics, Inc." on BioPortfolio

We have published hundreds of Proteostasis Therapeutics, Inc. news stories on BioPortfolio along with dozens of Proteostasis Therapeutics, Inc. Clinical Trials and PubMed Articles about Proteostasis Therapeutics, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Proteostasis Therapeutics, Inc. Companies in our database. You can also find out about relevant Proteostasis Therapeutics, Inc. Drugs and Medications on this site too.

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