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Shape Pharmaceuticals, Inc. Company Profile

20:21 EDT 17th June 2018 | BioPortfolio

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and psoriasis. Shape has an ongoing Phase 1b clinical study in CTCL patients and has completed a Phase 1b clinical study in psoriasis patients. The development of SHP-141 is being supported through a Therapeutic Accelerator Program partnership with the Leukemia & Lymphoma Society, which is providing funding of up to $3.3 million. Shape is a HealthCare Ventures funded Focused Company founded by James E. Bradner, M.D. of Dana-Farber Cancer Institute and Ralph Mazitschek, Ph.D. of Massachusetts General Hospital.


News Articles [713 Associated News Articles listed on BioPortfolio]

Trilobites: How the Shape of Your Ears Affects What You Hear

We’re able to locate sound because our brains grasp the shape of our ears. When that shape changes, we need time and practice to adapt.

Shape-shifting organic crystals use memory to improve plastic electronics

(University of Illinois at Urbana-Champaign) Researchers have identified a mechanism that triggers shape-memory phenomena in organic crystals used in plastic electronics. Shape-shifting structural mat...

Study: To prevent collapse of tropical forests, protect their shape

(University of Vermont) Scientists have made a fundamental discovery about how fires on the edges of tropical forests control their shape and stability. The study implies that when patches of tropical...

Novel programmed shape-morphing scaffolds developed to facilitate facile 3D endothelialization

Recently, a research team led by Dr. DU Xuemin at the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences created a new shape-morphing scaffold, enabling programmed de...

How the most common DNA mutation happens

Shape-shifters aren't just the stuff of fiction, they're real -- and they're inside our DNA. Researchers now describe how two mismatched bases in human DNA are able to change shape in order to avoid t...

Taurine deficiency in sperm causes male infertility

Sperm cells have a unique shape that allows them to travel. During fertilization, sperm pass through several physiological environments while still maintaining their shape, using poorly understood mec...

Getting Back in Shape in 2018? Great, but Do It Safely

TUESDAY, Jan. 2, 2018 -- Getting into shape or losing a few pounds is a worthy New Year's resolution, but one that comes with a warning: Take it slow. Jumping whole-hog into an exercise regime is a go...

Discovery of Gene Controlling Shape and Size of Wheat Spikelets Could Shape Future Crops

A new study conducted by a research team from John Innes Centre (JIC) has isolated a gene that controls the shape and size of wheat spikelets. The study focused on the genetics behind a specific mutan...

PubMed Articles [552 Associated PubMed Articles listed on BioPortfolio]

Letter--Incorporating Real-World Evidence and Patient Value Criteria into Value-Based Frameworks for Relapsed/Refractory Multiple Myeloma.

Orlowski has received research funding from Amgen, BioTheryX, Bristol-Myers Squibb, Celgene Corporation, and Takeda Pharmaceuticals; honoraria from Amgen, Bristol-Myers Squibb, Celgene Corporation, Ja...

Genetics of familial hypercholesterolemia: a tool for development of novel lipid lowering pharmaceuticals?

Familial hypercholesterolemia is characterized by high LDL cholesterol and an elevated risk to develop coronary heart disease. Mutations in LDL receptor-mediated cholesterol uptake are the main cause ...

Post-production handling and administration of protein pharmaceuticals and potential instability issues.

The safety and efficacy of protein pharmaceuticals depend not only on biological activity, but also on purity levels. Impurities may be process related due to limitations in manufacturing, or product ...

A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines and Pharmaceuticals.

Methods to incorporate deuterium and tritium atoms into organic molecules are valuable for medicinal chemistry. The prevalence of pyridines and diazines in pharmaceuticals means that new ways to label...

Eyebrow Position and Shape Favored by Korean Women.

The shape and position of the eyebrows are among the most important facial features from an esthetic point of view. However, significant cultural differences exist with respect to the eyebrow shape an...

Clinical Trials [396 Associated Clinical Trials listed on BioPortfolio]

Volumetric Three-dimensional Analysis of the Pediatric Upper Airway Shape Using Computed Tomography Imaging.

CT and MRI based measurements of the pediatric airway has changed the age-old cone shape concept of the pediatric airway and define airway shape as elliptical structure. The cone shape was...

Development and Validation of a Cloak Shape Device for Sham Pediatric Tuina

This study aims to evaluate the effectiveness of a Cloak Shape sham Pediatric Tuina device which can be applied in randomized controlled trials for Pediatric Tuina research.

Shape and Dimensions of the Upper Airway in Infants Using Computed Tomography Imaging

Cricoid is considered the narrowest part with the shape of airway defined as elliptical with the subglottis as the narrowest region. This study using imaging modality (2D CT images) is do...

PREVELLE Shape (CX002) Dermal Filler Protocol

The purpose of this study was to assess PREVELLE Shape (CX002), with respect to safety and efficacy for one year following treatment, for correction of facial nasolabial folds and when app...

Safety and Efficacy Study of SHAPE Gel in Alopecia Areata

The purpose of this study is to evaluate the efficacy and safety of SHAPE Gel applied topically to adult patients with alopecia areata of the scalp.

Companies [1439 Associated Companies listed on BioPortfolio]

Shape Pharmaceuticals, Inc.

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and p...

The Ashwell® Shape Chart

You can use THE ASHWELL® SHAPE CHART to work out the health risk attached to your own shape. This chart has been based on scientific evidence from the Universities of Cambridge and London in the Unit...

Shape Up The Nation

Shape Up The Nation is the first wellness company focused on leveraging the power of trusted social networks to promote healthy living. Founded in 2006, Shape Up The Nation has pi...

Shape Memory Medical Inc.

Shape Memory Medical Inc., based in Santa Clara, California, is committed to developing multiple medical therapies with their novel Shape Memory Polymers for embolization. Visit w...

Deciphera Pharmaceuticals, LLC

Deciphera Pharmaceuticals is a drug discovery and development company whose objective is to design, optimize, and introduce small molecule therapeutics for human clinical trials and the global pharmac...

More Information about "Shape Pharmaceuticals, Inc." on BioPortfolio

We have published hundreds of Shape Pharmaceuticals, Inc. news stories on BioPortfolio along with dozens of Shape Pharmaceuticals, Inc. Clinical Trials and PubMed Articles about Shape Pharmaceuticals, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Shape Pharmaceuticals, Inc. Companies in our database. You can also find out about relevant Shape Pharmaceuticals, Inc. Drugs and Medications on this site too.

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Pharmacy
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...


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