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Shape Pharmaceuticals, Inc. Company Profile

14:10 EST 17th December 2018 | BioPortfolio

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and psoriasis. Shape has an ongoing Phase 1b clinical study in CTCL patients and has completed a Phase 1b clinical study in psoriasis patients. The development of SHP-141 is being supported through a Therapeutic Accelerator Program partnership with the Leukemia & Lymphoma Society, which is providing funding of up to $3.3 million. Shape is a HealthCare Ventures funded Focused Company founded by James E. Bradner, M.D. of Dana-Farber Cancer Institute and Ralph Mazitschek, Ph.D. of Massachusetts General Hospital.


News Articles [563 Associated News Articles listed on BioPortfolio]

3D analysis of retinal tissue shows how to keep shape during organ growth

During the early development of an embryo, many tissues and organs already form their final shape. This shape has to be maintained while the organism keeps growing. As the correct shape of a tissue i...

GS9 Regulates Rice Grain Shape and Appearance

Identifying genes that determine grain shape can greatly help the breeding of better rice cultivars. Thus, Dong-Sheng Zhao from Yangzhou University in China and team studied the Grain Shape Gene on Ch...

Researchers discover genes that give vegetables their shape

Novel Embolization Device Uses Shape Memory Technology

A new compressible embolization plug expands to its pre-determined shape once correctly positioned in the peripheral vasculature.

Scientists Identify Protein that Influence Leaf Growth and Shape

Scientists at the Max Planck Institute for Plant Breeding Research in Cologne have discovered how a protein called LMI1 controls leaf growth and shape. Francesco Vuolo and colleagues are investigating...

Shape-shifting cell breakthrough

A new computational model gives a clearer picture of the structure and mechanics of soft, shape-changing cells that could provide a better understanding of cancerous tumor growth, wound healing, and e...

Studying Neanderthal Brain Development, One (Indirect) CT Scan at a Time

When you were born, your brain was more elongated than it is now; it rounded out into its more globular shape as you grew up and crammed it full of knowledge. Neanderthals, it appears, were born with ...

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpent...

PubMed Articles [551 Associated PubMed Articles listed on BioPortfolio]

Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals.

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects ...

Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective.

Chiral pharmaceuticals (CPs), including non-steroid anti-inflammatory drugs (NSAIDs), β-blockers and some herbicide and pesticides, are widely used in aquaculture, clinical treatment and many other f...

Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: Hourly variation.

The removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency clos...

Computer-assisted analysis of intracerebral haemorrhage shape and density.

Shape and density of intracerebral haemorrhage (ICH) is associated with higher risk of poor treatment outcome. However, methods of those features assessment are still inconclusive. Therefore, we decid...

Effects of pharmaceuticals on microbial communities and activity of soil enzymes in mesocosm-scale constructed wetlands.

Cyperus alternifolius based mesocosm-scale constructed wetland was employed to remove pharmaceuticals. We investigated the microbial community composition using phosphor lipid fatty acids (PFLAs) anal...

Clinical Trials [439 Associated Clinical Trials listed on BioPortfolio]

Volumetric Three-dimensional Analysis of the Pediatric Upper Airway Shape Using Computed Tomography Imaging.

CT and MRI based measurements of the pediatric airway has changed the age-old cone shape concept of the pediatric airway and define airway shape as elliptical structure. The cone shape was...

Development and Validation of a Cloak Shape Device for Sham Pediatric Tuina

This study aims to evaluate the effectiveness of a Cloak Shape sham Pediatric Tuina device which can be applied in randomized controlled trials for Pediatric Tuina research.

Shape and Dimensions of the Upper Airway in Infants Using Computed Tomography Imaging

Cricoid is considered the narrowest part with the shape of airway defined as elliptical with the subglottis as the narrowest region. This study using imaging modality (2D CT images) is do...

PREVELLE Shape (CX002) Dermal Filler Protocol

The purpose of this study was to assess PREVELLE Shape (CX002), with respect to safety and efficacy for one year following treatment, for correction of facial nasolabial folds and when app...

Safety and Efficacy Study of SHAPE Gel in Alopecia Areata

The purpose of this study is to evaluate the efficacy and safety of SHAPE Gel applied topically to adult patients with alopecia areata of the scalp.

Companies [1461 Associated Companies listed on BioPortfolio]

Shape Pharmaceuticals, Inc.

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and p...

The Ashwell® Shape Chart

You can use THE ASHWELL® SHAPE CHART to work out the health risk attached to your own shape. This chart has been based on scientific evidence from the Universities of Cambridge and London in the Unit...

Shape Up The Nation

Shape Up The Nation is the first wellness company focused on leveraging the power of trusted social networks to promote healthy living. Founded in 2006, Shape Up The Nation has pi...

Shape Memory Medical Inc.

Shape Memory Medical Inc., based in Santa Clara, California, is committed to developing multiple medical therapies with their novel Shape Memory Polymers for embolization. Visit w...

Deciphera Pharmaceuticals, LLC

Deciphera Pharmaceuticals is a drug discovery and development company whose objective is to design, optimize, and introduce small molecule therapeutics for human clinical trials and the global pharmac...

More Information about "Shape Pharmaceuticals, Inc." on BioPortfolio

We have published hundreds of Shape Pharmaceuticals, Inc. news stories on BioPortfolio along with dozens of Shape Pharmaceuticals, Inc. Clinical Trials and PubMed Articles about Shape Pharmaceuticals, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Shape Pharmaceuticals, Inc. Companies in our database. You can also find out about relevant Shape Pharmaceuticals, Inc. Drugs and Medications on this site too.

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Pharmacy
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...


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