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Shape Pharmaceuticals, Inc. Company Profile

07:47 EDT 21st September 2018 | BioPortfolio

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and psoriasis. Shape has an ongoing Phase 1b clinical study in CTCL patients and has completed a Phase 1b clinical study in psoriasis patients. The development of SHP-141 is being supported through a Therapeutic Accelerator Program partnership with the Leukemia & Lymphoma Society, which is providing funding of up to $3.3 million. Shape is a HealthCare Ventures funded Focused Company founded by James E. Bradner, M.D. of Dana-Farber Cancer Institute and Ralph Mazitschek, Ph.D. of Massachusetts General Hospital.


News Articles [584 Associated News Articles listed on BioPortfolio]

3D analysis of retinal tissue shows how to keep shape during organ growth

During the early development of an embryo, many tissues and organs already form their final shape. This shape has to be maintained while the organism keeps growing. As the correct shape of a tissue i...

Trilobites: How the Shape of Your Ears Affects What You Hear

We’re able to locate sound because our brains grasp the shape of our ears. When that shape changes, we need time and practice to adapt.

GS9 Regulates Rice Grain Shape and Appearance

Identifying genes that determine grain shape can greatly help the breeding of better rice cultivars. Thus, Dong-Sheng Zhao from Yangzhou University in China and team studied the Grain Shape Gene on Ch...

Study: To prevent collapse of tropical forests, protect their shape

(University of Vermont) Scientists have made a fundamental discovery about how fires on the edges of tropical forests control their shape and stability. The study implies that when patches of tropical...

Novel programmed shape-morphing scaffolds developed to facilitate facile 3D endothelialization

Recently, a research team led by Dr. DU Xuemin at the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences created a new shape-morphing scaffold, enabling programmed de...

Novel Embolization Device Uses Shape Memory Technology

A new compressible embolization plug expands to its pre-determined shape once correctly positioned in the peripheral vasculature.

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpent...

Fish body shape holds key to make fishery management cheaper, easier

(Smithsonian) A simple body-shape analysis can reveal what part of the ocean a fish came from, according to a new study from Smithsonian scientists working to develop better tools for managing small-s...

PubMed Articles [542 Associated PubMed Articles listed on BioPortfolio]

Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals.

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects ...

Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: Hourly variation.

The removal efficiency of pharmaceuticals in wastewater treatment plants (WWTPs) is variable and some of these compounds pass these plants almost intact and others presenting a removal efficiency clos...

Letter--Incorporating Real-World Evidence and Patient Value Criteria into Value-Based Frameworks for Relapsed/Refractory Multiple Myeloma.

Orlowski has received research funding from Amgen, BioTheryX, Bristol-Myers Squibb, Celgene Corporation, and Takeda Pharmaceuticals; honoraria from Amgen, Bristol-Myers Squibb, Celgene Corporation, Ja...

Computer-assisted analysis of intracerebral haemorrhage shape and density.

Shape and density of intracerebral haemorrhage (ICH) is associated with higher risk of poor treatment outcome. However, methods of those features assessment are still inconclusive. Therefore, we decid...

Post-production handling and administration of protein pharmaceuticals and potential instability issues.

The safety and efficacy of protein pharmaceuticals depend not only on biological activity, but also on purity levels. Impurities may be process related due to limitations in manufacturing, or product ...

Clinical Trials [422 Associated Clinical Trials listed on BioPortfolio]

Volumetric Three-dimensional Analysis of the Pediatric Upper Airway Shape Using Computed Tomography Imaging.

CT and MRI based measurements of the pediatric airway has changed the age-old cone shape concept of the pediatric airway and define airway shape as elliptical structure. The cone shape was...

Development and Validation of a Cloak Shape Device for Sham Pediatric Tuina

This study aims to evaluate the effectiveness of a Cloak Shape sham Pediatric Tuina device which can be applied in randomized controlled trials for Pediatric Tuina research.

Shape and Dimensions of the Upper Airway in Infants Using Computed Tomography Imaging

Cricoid is considered the narrowest part with the shape of airway defined as elliptical with the subglottis as the narrowest region. This study using imaging modality (2D CT images) is do...

PREVELLE Shape (CX002) Dermal Filler Protocol

The purpose of this study was to assess PREVELLE Shape (CX002), with respect to safety and efficacy for one year following treatment, for correction of facial nasolabial folds and when app...

Safety and Efficacy Study of SHAPE Gel in Alopecia Areata

The purpose of this study is to evaluate the efficacy and safety of SHAPE Gel applied topically to adult patients with alopecia areata of the scalp.

Companies [1448 Associated Companies listed on BioPortfolio]

Shape Pharmaceuticals, Inc.

Shape Pharmaceuticals, Inc. is developing SHP-141, a novel, topical, “soft-drug” HDAC inhibitor for the treatment of patients with cutaneous T cell lymphoma (CTCL) and p...

The Ashwell® Shape Chart

You can use THE ASHWELL® SHAPE CHART to work out the health risk attached to your own shape. This chart has been based on scientific evidence from the Universities of Cambridge and London in the Unit...

Shape Up The Nation

Shape Up The Nation is the first wellness company focused on leveraging the power of trusted social networks to promote healthy living. Founded in 2006, Shape Up The Nation has pi...

Shape Memory Medical Inc.

Shape Memory Medical Inc., based in Santa Clara, California, is committed to developing multiple medical therapies with their novel Shape Memory Polymers for embolization. Visit w...

Deciphera Pharmaceuticals, LLC

Deciphera Pharmaceuticals is a drug discovery and development company whose objective is to design, optimize, and introduce small molecule therapeutics for human clinical trials and the global pharmac...

More Information about "Shape Pharmaceuticals, Inc." on BioPortfolio

We have published hundreds of Shape Pharmaceuticals, Inc. news stories on BioPortfolio along with dozens of Shape Pharmaceuticals, Inc. Clinical Trials and PubMed Articles about Shape Pharmaceuticals, Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Shape Pharmaceuticals, Inc. Companies in our database. You can also find out about relevant Shape Pharmaceuticals, Inc. Drugs and Medications on this site too.

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Pharmacy
Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...


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