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Bionomics (ASX: BNO) is an Australian based international biotechnology company which discovers and develops innovative therapeutics for cancer and diseases of the central nervous system. Bionomics has small molecule and antibody product development programs in the areas of cancer, anxiety, and memory loss. Its oncology approach includes cancer stem cell therapeutics as well as vascular disruption in solid tumours.
BNC105, which is undergoing Phase II clinical development in a range of solid tumour types, is based upon the identification of a novel compound that potently and selectively restricts blood flow within tumours. BNC105 offers blockbuster potential if successfully developed. A clinical program is also underway for the treatment of anxiety disorders and depression based on IW-2143(BNC210), a novel compound which stimulates neurite outgrowth. IW-2143 is partnered with Ironwood Pharmaceuticals.
Bionomics' discovery and development activities are driven by its four proprietary technology platforms: Angene®, a drug discovery platform which incorporates a variety of genomics tools to identify and validate novel angiogenesis targets (involved in the formation of new blood vessels); MultiCore®, a diversity orientated chemistry platform for the discovery of small molecule drugs; ionX® , a set of novel technologies for the identification of drugs targeting ion channels for diseases of the central nervous system; and CSC Rx Discovery™, which identifies antibody and small molecule therapeutics that inhibit the growth of cancer stem cells. These platforms drive Bionomics’ pipeline and underpin its established business strategy of securing partners for its key compounds.
Bionomics has a portfolio of drug candidates with potentially significant end-user markets with unmet clinical needs. Bionomics' pipeline includes BNC105, a "best in class" vascular disrupting agent for the treatment of solid tumours which is currently in Phase II clinical trials; BNC210, under development for the treatment of anxiety disorders by Bionomics' partner Ironwood Pharmaceuticals; and Kv1.3 blockers for the treatment of Multiple Sclerosis and other autoimmune conditions in partnership with Merck Serono. The latest addition to the pipeline is the Alpha 7 program which targets conditions where memory is impaired, including Alzheimer's Disease.
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Edison Investment Research - Pharmaceutical & healthcare - Bionomics: Bionomics announced on 23 May 2018 it has initiated a Phase IIa study of its α7 nicotinic receptor inhibitor for the treatme...
In this episode of PharmaTelevision News Review, Fintan Walton talks to Dr Deborah Rathjen, CEO and MD of Bionomics Ltd.
Edison Investment Research - Pharmaceutical & healthcare - Bionomics: Bionomics announced on 9 July 2018 that it had completed treatment in its 193-patient Phase II clinical study of BNC210 for post-t...
Edison Investment Research - Pharmaceutical & healthcare - Bionomics: The fiscal year 2018, which ended in June, was a major transition for Bionomics as it realigned itself to focus on disorders of th...
Edison Investment Research - Pharmaceutical & healthcare - Bionomics: We are re-initiating coverage on Bionomics, a pharmaceutical company developing drugs for neuropsychiatric indications and oncolog...
In this episode of PharmaTelevision News Review, Fintan Walton talks to Deborah Rathjen, CEO and Managing Director of Bionomics Ltd.
Bionomics has started a Phase II clinical trial of BNC210 for treating agitation in elderly patients. The trial will be...Read More... The post Bionomics begins Phase II trial of BNC210 to treat agita...
In this episode of PharmaTelevision News Review, filmed at AusBio 2012 in Melbourne, Australia, Fintan Walton talks to Deborah Rathjen, CEO and MD at Bionomics
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Bionomics (ASX: BNO) is an Australian based international biotechnology company which discovers and develops innovative therapeutics for cancer and diseases of the central nervous system. Biono...
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We have published hundreds of Bionomics Limited news stories on BioPortfolio along with dozens of Bionomics Limited Clinical Trials and PubMed Articles about Bionomics Limited for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Bionomics Limited Companies in our database. You can also find out about relevant Bionomics Limited Drugs and Medications on this site too.
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