Bionomics Limited Company Profile

02:09 EDT 18th June 2018 | BioPortfolio

Bionomics (ASX: BNO) is an Australian based international biotechnology company which discovers and develops innovative therapeutics for cancer and diseases of the central nervous system. Bionomics has small molecule and antibody product development programs in the areas of cancer, anxiety, and memory loss. Its oncology approach includes cancer stem cell therapeutics as well as vascular disruption in solid tumours.
BNC105, which is undergoing Phase II clinical development in a range of solid tumour types, is based upon the identification of a novel compound that potently and selectively restricts blood flow within tumours. BNC105 offers blockbuster potential if successfully developed. A clinical program is also underway for the treatment of anxiety disorders and depression based on IW-2143(BNC210), a novel compound which stimulates neurite outgrowth. IW-2143 is partnered with Ironwood Pharmaceuticals.

Bionomics' discovery and development activities are driven by its four proprietary technology platforms: Angene®, a drug discovery platform which incorporates a variety of genomics tools to identify and validate novel angiogenesis targets (involved in the formation of new blood vessels); MultiCore®, a diversity orientated chemistry platform for the discovery of small molecule drugs; ionX® , a set of novel technologies for the identification of drugs targeting ion channels for diseases of the central nervous system; and CSC Rx Discovery™, which identifies antibody and small molecule therapeutics that inhibit the growth of cancer stem cells. These platforms drive Bionomics’ pipeline and underpin its established business strategy of securing partners for its key compounds.


Bionomics has a portfolio of drug candidates with potentially significant end-user markets with unmet clinical needs. Bionomics' pipeline includes BNC105, a "best in class" vascular disrupting agent for the treatment of solid tumours which is currently in Phase II clinical trials; BNC210, under development for the treatment of anxiety disorders by Bionomics' partner Ironwood Pharmaceuticals; and Kv1.3 blockers for the treatment of Multiple Sclerosis and other autoimmune conditions in partnership with Merck Serono. The latest addition to the pipeline is the Alpha 7 program which targets conditions where memory is impaired, including Alzheimer's Disease.


31 Dalgleish Street


Phone: +618 8354 6100
Fax: +618 8354 6199

News Articles [39 Associated News Articles listed on BioPortfolio]

Bionomics (BNO) - Phase IIa in agitation of the elderly initiated

Edison Investment Research - Pharmaceutical & healthcare - Bionomics: Bionomics announced on 23 May 2018 it has initiated a Phase IIa study of its α7 nicotinic receptor inhibitor for the treatme...

Bionomics (BNO) - Novel mechanisms in drug discovery

Edison Investment Research - Pharmaceutical & healthcare - Bionomics: We are re-initiating coverage on Bionomics, a pharmaceutical company developing drugs for neuropsychiatric indications and oncolog...

Bionomics begins Phase II trial of BNC210 to treat agitation

Bionomics has started a Phase II clinical trial of BNC210 for treating agitation in elderly patients. The trial will be...Read More... The post Bionomics begins Phase II trial of BNC210 to treat agita...

Hardman & Co Research: Bionomics Ltd (BNO) initiation report: Channelling expertise in CNS drugs

Dow Jones received a payment from EQS/DGAP to publish this press release. Hardman & Co Hardman & Co Research: Bionomics Ltd (BNO) initiation report: Channelling expertise in CNS drugs 07-Feb-2018 ...

Bionomics Ltd BNO Financial and Strategic SWOT Analysis Review [Report Updated: 09032018] Prices from USD $300

SummaryBionomics Ltd Bionomics is a biopharmaceutical company that discovers and develops treatments for cancer, and central nervous system disorders such as anxiety, depression and Alzheimer's diseas...

Genetic Technologies Limited: Update on Strategic Alliance

MELBOURNE, Australia, Feb. 12, 2018 (GLOBE NEWSWIRE) -- Genetic Technologies Limited (ASX:GTG) (NASDAQ:GENE) (“Company”, “GTG”), wishes to advise that the Company is presently in discussi...

Genetic Technologies Limited: Project Shivom Strategic Alliance

MELBOURNE, Australia, March 06, 2018 (GLOBE NEWSWIRE) -- Genetic Technologies Limited (ASX:GTG)  (NASDAQ:GENE) (“Company”, “GTG”) a diversified molecular diagnostics company; provider of...

Hardman & Co Research: Bionomics (BNO): A big deal in oncology?

Hardman & Co Research 04-Jun-2018 / 06:30 GMT/BST Hardman & Co Research: A big deal in oncology? Bionomics (BNO) is an Australian biopharmaceutical company specialising in ion channel dr...

PubMed Articles [4 Associated PubMed Articles listed on BioPortfolio]

Bionomics of Anopheles (Nyssorhynchus) albimanus (Diptera: Culicidae) in two villages of the Wayúu people, Riohacha, La Guajira, Colombia.

Riohacha, capital of the department of La Guajira, reports the highest rates for malaria in the department, and the most vulnerable people are those of the Wayúu indigenous group.

Description of fourth instar larva and pupa of Atrichopogon delpontei Cavalieri and Chiossone (Diptera: Ceratopogonidae) from Brazilian Amazonia.

The fourth instar larva and pupa of Atrichopogon delpontei Cavalieri and Chiossone are described for the first time. The immatures were collected from stream margins in the northern Brazilian states R...

Bionomics of Anopheles subpictus (Diptera: Culicidae) in a Malaria Endemic Area, Southeastern Iran.

Anopheles subpictus Grassi is considered a secondary malaria vector in parts of Asia. The current study determined some ecological and bionomical characteristics of this species in southeastern Iran. ...

Influence of Rearing Substrates and Nontarget Hosts on the Bionomics of the Tachinid Parasitoid Nemorilla maculosa (Diptera: Tachinidae).

The tachinid Nemorilla maculosa Meigen (Diptera: Tachinidae) was introduced from Taiwan to Benin for evaluating its potential as a biocontrol candidate against the cowpea pest Maruca vitrata (Fabriciu...

Clinical Trials [0 Results]


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