Thubrikar Aortic Valve, Inc. Company Profile

16:17 EDT 21st June 2018 | BioPortfolio

Thubrikar Aortic Valve, Inc., founded in October 2010, is a privately held medical device company headquartered in Norristown, PA. The Company has developed a low-profile, bovine pericardial, self-expanding percutaneous valve for transcatheter aortic valve implantation (TAVI) - called the “Optimum TAV” - as a treatment option for aortic stenosis. Optimum TAV was designed to mimic the natural aortic valve, improve durability, and to additionally be used in valve-in-valve procedures and bicuspid patients. The Company is also designing delivery systems for transfemoral, transapical, subclavian, and direct aortic access points. More information can be found at

News Articles [321 Associated News Articles listed on BioPortfolio]

A New Valve Type for Transcatheter Aortic-Valve Replacement?

In patients with severe aortic stenosis, a new mechanically expanded valve is noninferior to an established self-expanding valve, but problems remain.

Researchers build molecular networks of calcific aortic valve disease

Calcific aortic valve disease - a disease that leaves the aortic valve stiff and calcified, preventing blood flow from the heart into the aorta - affects one quarter of the U.S. population aged 65 and...

Self-Expanding Heart Valve Treats Severe Aortic Stenosis

A novel transcatheter heart valve (THV) valve aids treats patients with severe aortic stenosis requiring aortic valve replacement (AVR).

Efficacy of a Repositionable, Retrievable Aortic Valve

This study aimed to confirm the safety and efficacy of the Lotus Valve, a novel repositionable and fully retrievable bioprosthetic aortic valve. European Heart Journal

Rapid Deployment Valve for Aortic Stenosis Ups Stroke Risk

FRIDAY, April 13, 2018 -- For patients with aortic valve stenosis, treatment with a rapid deployment valve (RDV) is associated with increased rates of new-onset pacemaker implantation and disabling st...

A molecular atlas of calcific aortic valve disease

(Brigham and Women's Hospital) A team of researchers from BWH has comprehensively analyzed gene expression and protein distribution in human aortic valves obtained from valve replacement surgery. Thei...

Further Hazards of Mismatched Surgical Aortic Valve Prostheses

Survival suffers after a later transcatheter valve-in-valve procedure, should it be needed, if the failed surgical prosthetic valve wasn't originally up to the patient's cardiac output needs. Medsc...

In Anticoagulation After Mechanical Aortic-Valve Replacement, How Low Can You Go?

After placement of the On-X mechanical aortic valve, high-risk patients can be managed safely with reduced-intensity warfarin, but dual antiplatelet therapy is not appropriate for low-risk patients.

PubMed Articles [1241 Associated PubMed Articles listed on BioPortfolio]

Aortic Valve-in-Valve in Externally Mounted Bioprosthesis: A Safe Treatment Option for Bioprosthetic Structural Valve Dysfunction.

Aortic valve-in-valve implantation for prosthetic valve dysfunction is a good alternative to reoperative valve replacement. There are some limitations to this approach including the risk of coronary o...

Transcaval Valve-in-Valve-in-Valve Aortic Valve Replacement for Bioprosthetic Valve Degeneration.

A 74-year-old man presented with progressive dyspnea on exertion. History included peripheral arterial disease and coronary artery bypass grafting with aortic valve replacement 12 years ago. Subsequen...

The impact of coronary anomalies on the outcome in aortic valve surgery: comparison of bicuspid aortic valve versus tricuspid aortic valve morphotype.

The association of anomalous anatomy of coronary arteries and bicuspid aortic valve (BAV) has been sporadically reported. Our aim was to evaluate the prevalence of coronary anomalies between BAV and t...

Transcatheter valve-in-valve implantation in a patient with a degenerative sutureless aortic bioprosthesis: case report and literature review.

Sutureless aortic bioprostheses (SAB) provide shorter aortic cross-clamp time and cardiopulmonary bypass duration compared to conventional aortic valve replacement. Similarly to other bioprostheses, r...

Diagnostic significance of three-dimensional echocardiography in asymptomatic unicuspid aortic valve.

Unicuspid aortic valve (UAV) is a rare congenital anomaly of aorta associated with a faster progress of valvular dysfunction, aortic dilatation and with necessity for more frequent controls and precis...

Clinical Trials [1029 Associated Clinical Trials listed on BioPortfolio]

Minimally Invasive Aortic Valve Replacement Versus Conventional Aortic Valve Replacement. a Long Term Registry

The aim of the present study is to assess in a "real life" caselist the outcome of three different surgical approches for isolated aortic valve surgery in terms of surgery times, morbidity...

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA

To evaluate the safety and performance of the HLT System in patients with severe aortic stenosis who present at high risk for aortic valve replacement surgery.

Ascending Aortic Dilation in BiAV After TAVR

This study sought to evaluate changes in ascending aorta size after transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve (BiAV) compared with patients with ...

Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve

This is a trial to demonstrate the safety and effectiveness of the Mitroflow Aortic Heart Valve when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis.

Finnish Registry of Transcatheter and Surgical Aortic Valve Replacement for Aortic Valve Stenosis: FinnValve Registry

The FinnValve investigators planned a nationwide registry to investigate the early and late outcome of transcatheter aortic valve implantation (TAVI) compared to surgical aortic valve repl...

Companies [80 Associated Companies listed on BioPortfolio]

Thubrikar Aortic Valve, Inc.

Thubrikar Aortic Valve, Inc., founded in October 2010, is a privately held medical device company headquartered in Norristown, PA. The Company has developed a low-profile, bovine ...

BioStable Science & Engineering, Inc.

BioStable Science & Engineering is a cardiovascular device company focused on developing and commercializing proprietary valve repair technologies that provide an alternative to v...

JC Medical, Inc.

JC Medical, Inc. is a private, venture-backed medical device company transforming the treatment of Aortic Valve Disease, a growing clinical need in the face of the prevalence of h...

JenaValve Technology, Inc.

JenaValve Technology, Inc., a U.S. corporation with primary operations in Munich, Germany, develops, manufactures and markets transcatheter aortic valve implantation systems (TAVI...

JenaValve Technology GmbH

JenaValve Technology is a medical device company focused on developing transcatheter-delivered aortic valve systems to treat patients suffering from aortic valve disease. The comp...

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