Thubrikar Aortic Valve, Inc. Company Profile

02:03 EDT 18th March 2018 | BioPortfolio

Thubrikar Aortic Valve, Inc., founded in October 2010, is a privately held medical device company headquartered in Norristown, PA. The Company has developed a low-profile, bovine pericardial, self-expanding percutaneous valve for transcatheter aortic valve implantation (TAVI) - called the “Optimum TAV” - as a treatment option for aortic stenosis. Optimum TAV was designed to mimic the natural aortic valve, improve durability, and to additionally be used in valve-in-valve procedures and bicuspid patients. The Company is also designing delivery systems for transfemoral, transapical, subclavian, and direct aortic access points. More information can be found at

News Articles [322 Associated News Articles listed on BioPortfolio]

A New Valve Type for Transcatheter Aortic-Valve Replacement?

In patients with severe aortic stenosis, a new mechanically expanded valve is noninferior to an established self-expanding valve, but problems remain.

JACC publishes appropriate use criteria for treating severe aortic stenosis

Published online Oct. 17

Efficacy of a Repositionable, Retrievable Aortic Valve

This study aimed to confirm the safety and efficacy of the Lotus Valve, a novel repositionable and fully retrievable bioprosthetic aortic valve. European Heart Journal

Aortic Valve Replacement Improves Survival in High-risk Patients

Aortic valve replacement (AVR) improves survival in patients with severe aortic regurgitation and severely reduced left-ventricular ejection fraction (LVEF), according to a database review. Reuters ...

Further Hazards of Mismatched Surgical Aortic Valve Prostheses

Survival suffers after a later transcatheter valve-in-valve procedure, should it be needed, if the failed surgical prosthetic valve wasn't originally up to the patient's cardiac output needs. Medsc...

Researchers ID new subset of patients who may benefit from aortic valve replacement

Clinical guidelines don’t recommend valve replacement for patients with severe aortic stenosis (AS) dem

What’s the Best Technique to Measure Low-flow, Low-gradient Aortic Stenosis?

In patients with low-flow, low-gradient aortic stenosis, current guideline-based criteria for identifying true severe aortic stenosis did not predict aortic stenosis severity or survival. Calculation ...

Depression at Time of Aortic Valve Replacement Tied to Higher Mortality Risk

Older adults undergoing transcatheter or surgical aortic valve replacement (TAVR or SAVR) who are depressed face increased mortality risk in the year after the procedure...

PubMed Articles [1252 Associated PubMed Articles listed on BioPortfolio]

Full metal jacket: transfemoral aortic valve implantation for regurgitant valve after endovascular aortic repair†.

Transfemoral aortic valve implantation has become an almost routine interventional procedure for severe aortic stenosis in high-risk patients. Over time an increased number of experiences has led to u...

The impact of coronary anomalies on the outcome in aortic valve surgery: comparison of bicuspid aortic valve versus tricuspid aortic valve morphotype.

The association of anomalous anatomy of coronary arteries and bicuspid aortic valve (BAV) has been sporadically reported. Our aim was to evaluate the prevalence of coronary anomalies between BAV and t...

TAVI for Failed Valve-Sparing Operations: In-Hospital and Mid-Term Outcome.

Although transcatheter aortic valve implantation (TAVI) is a steadily expanding treatment for the pathology of the aortic valve, its role in the replacement of native aortic valves following valve-spa...

Transcatheter valve-in-valve implantation in a patient with a degenerative sutureless aortic bioprosthesis: case report and literature review.

Sutureless aortic bioprostheses (SAB) provide shorter aortic cross-clamp time and cardiopulmonary bypass duration compared to conventional aortic valve replacement. Similarly to other bioprostheses, r...

Minimally Invasive Versus Transcatheter and Surgical Aortic Valve Replacement: A Propensity Matched Study.

An increasing number of options exist for the treatment of severe symptomatic aortic stenosis. The study aim was to compare short-term outcomes in patients undergoing surgical aortic valve replacement...

Clinical Trials [979 Associated Clinical Trials listed on BioPortfolio]

Minimally Invasive Aortic Valve Replacement Versus Conventional Aortic Valve Replacement. a Long Term Registry

The aim of the present study is to assess in a "real life" caselist the outcome of three different surgical approches for isolated aortic valve surgery in terms of surgery times, morbidity...

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA

To evaluate the safety and performance of the HLT System in patients with severe aortic stenosis who present at high risk for aortic valve replacement surgery.

Ascending Aortic Dilation in BiAV After TAVR

This study sought to evaluate changes in ascending aorta size after transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve (BiAV) compared with patients with ...

Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve

This is a trial to demonstrate the safety and effectiveness of the Mitroflow Aortic Heart Valve when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis.

Finnish Registry of Transcatheter and Surgical Aortic Valve Replacement for Aortic Valve Stenosis: FinnValve Registry

The FinnValve investigators planned a nationwide registry to investigate the early and late outcome of transcatheter aortic valve implantation (TAVI) compared to surgical aortic valve repl...

Companies [79 Associated Companies listed on BioPortfolio]

Thubrikar Aortic Valve, Inc.

Thubrikar Aortic Valve, Inc., founded in October 2010, is a privately held medical device company headquartered in Norristown, PA. The Company has developed a low-profile, bovine ...

BioStable Science & Engineering, Inc.

BioStable Science & Engineering is a cardiovascular device company focused on developing and commercializing proprietary valve repair technologies that provide an alternative to v...

JenaValve Technology, Inc.

JenaValve Technology, Inc., a U.S. corporation with primary operations in Munich, Germany, develops, manufactures and markets transcatheter aortic valve implantation systems (TAVI...

JenaValve Technology GmbH

JenaValve Technology is a medical device company focused on developing transcatheter-delivered aortic valve systems to treat patients suffering from aortic valve disease. The comp...

JenaValve Technology

JenaValve Technology is a medical device company focused on developing transcatheter valve implantation systems to treat patients suffering from aortic valve disease. The c...

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