Thubrikar Aortic Valve, Inc. Company Profile

14:12 EST 9th December 2018 | BioPortfolio

Thubrikar Aortic Valve, Inc., founded in October 2010, is a privately held medical device company headquartered in Norristown, PA. The Company has developed a low-profile, bovine pericardial, self-expanding percutaneous valve for transcatheter aortic valve implantation (TAVI) - called the “Optimum TAV” - as a treatment option for aortic stenosis. Optimum TAV was designed to mimic the natural aortic valve, improve durability, and to additionally be used in valve-in-valve procedures and bicuspid patients. The Company is also designing delivery systems for transfemoral, transapical, subclavian, and direct aortic access points. More information can be found at

News Articles [421 Associated News Articles listed on BioPortfolio]

Thubrikar and Labcor Strengthen Partnership with Nearly $1 Million Investment in Thubrikar

Thubrikar Aortic Valve, Inc., a privately held medical device company developing a next-generation Transcatheter Aortic Valve Implantation (TAVI) system, announced today the inves...

Valve-in-Valve TAVR Matches 'Benchmark' of Native TAVR

Outcomes were similar or better compared with those of native-valve transcatheter aortic valve replacement, though longer follow-up will tell if it becomes the default strategy for most failed aortic ...

Lipoprotein Levels May Inform Timing of Aortic Valve Replacement

(MedPage Today) -- Linear relationship seen with worsening aortic valve stenosis

Patient Outcomes Tied to Valve Replacement Volume

MONDAY, Nov. 19, 2018 -- Hospitals with high caseloads of both surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) have the best outcomes, according to a study p...

Elevated Blood Pressure Linked to Aortic Valve Disease

WEDNESDAY, Oct. 3, 2018 -- Long-term exposure to elevated blood pressure (BP) is associated with increased risk for aortic valve stenosis (AS) and aortic regurgitation (AR), according to a study publi...

LivaNova completes enrollment for global aortic valve replacement clinical trial

The company welcomed the recently updated interventional procedures guidance for sutureless aortic valve replacement issued by the U.K. National Institute for Health and Care Excellence (NICE), which ...

When Can Surgeons Perform Aortic Valve Replacement Safely After a Stroke?

Interrogation of Danish administrative registry data demonstrated that a stroke within three to four months of aortic valve surgery was associated with a higher rate of perioperative stroke.

In Anticoagulation After Mechanical Aortic-Valve Replacement, How Low Can You Go?

After placement of the On-X mechanical aortic valve, high-risk patients can be managed safely with reduced-intensity warfarin, but dual antiplatelet therapy is not appropriate for low-risk patients.

PubMed Articles [1276 Associated PubMed Articles listed on BioPortfolio]

Aortic Valve-in-Valve in Externally Mounted Bioprosthesis: A Safe Treatment Option for Bioprosthetic Structural Valve Dysfunction.

Aortic valve-in-valve implantation for prosthetic valve dysfunction is a good alternative to reoperative valve replacement. There are some limitations to this approach including the risk of coronary o...

Surgical aortic valve replacement for valve-in-valve trans-catheter aortic valve dysfunction in the patient with a small aortic annulus.

Meta-analysis of Valve-in-Valve Transcatheter versus Redo Surgical Aortic Valve Replacement.

 The objective of this study was to determine whether valve-in-valve transcatheter aortic valve implantation (VIV-TAVI) is associated with better survival than redo surgical aortic valve replacement...

Valve-sparing aortic root replacement combined with bicuspidization for a quadricuspid aortic valve.

Quadricuspid aortic valves are rare congenital malformations. Although aortic valve replacement is the first-choice treatment in most cases, aortic valve repair using a tricuspidization procedure has ...

Reconstruction of regurgitant bicuspid aortic valve (Sievers type 1, L/R, I) with raphe resection and concomitant pericardial patch-augmentation: A standardized approach.

A major limitation of the more widespread application of aortic valve reconstruction is the lack of a common framework for valve assessment that could  be used to guide a standardized approach to ao...

Clinical Trials [1155 Associated Clinical Trials listed on BioPortfolio]

Aortic Root Enlargement in Aortic Valve Replacement

Aortic valve disease is a progressive illness that varies from minor valve thickening lacking obstruction of blood stream to severe calcification and alteration of the valve leading to wea...

Minimally Invasive Aortic Valve Replacement Versus Conventional Aortic Valve Replacement. a Long Term Registry

The aim of the present study is to assess in a "real life" caselist the outcome of three different surgical approches for isolated aortic valve surgery in terms of surgery times, morbidity...

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA

To evaluate the safety and performance of the HLT System in patients with severe aortic stenosis who present at high risk for aortic valve replacement surgery.

Ascending Aortic Dilation in BiAV After TAVR

This study sought to evaluate changes in ascending aorta size after transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve (BiAV) compared with patients with ...

Clinical Investigation Of The Mitroflow Aortic Pericardial Heart Valve

This is a trial to demonstrate the safety and effectiveness of the Mitroflow Aortic Heart Valve when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis.

Companies [81 Associated Companies listed on BioPortfolio]

Thubrikar Aortic Valve, Inc.

Thubrikar Aortic Valve, Inc., founded in October 2010, is a privately held medical device company headquartered in Norristown, PA. The Company has developed a low-profile, bovine ...

BioStable Science & Engineering, Inc.

BioStable Science & Engineering is a cardiovascular device company focused on developing and commercializing proprietary valve repair technologies that provide an alternative to v...

JC Medical, Inc.

JC Medical, Inc. is a private, venture-backed medical device company transforming the treatment of Aortic Valve Disease, a growing clinical need in the face of the prevalence of h...

JenaValve Technology, Inc.

JenaValve Technology, Inc., a U.S. corporation with primary operations in Munich, Germany, develops, manufactures and markets transcatheter aortic valve implantation systems (TAVI...

JenaValve Technology GmbH

JenaValve Technology is a medical device company focused on developing transcatheter-delivered aortic valve systems to treat patients suffering from aortic valve disease. The comp...

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