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ENDECE Neural Company Profile

05:00 EDT 22nd September 2018 | BioPortfolio

ENDECE Neural is a private biotechnology company at the forefront of developing therapies to repair and potentially reverse damage caused by devastating neurological diseases such as multiple sclerosis (MS). A wholly owned subsidiary of ENDECE LLC, ENDECE Neural was founded in 2011 to focus on the development of what could be the first drug capable of inducing remyelination of damaged nerves in patients with MS. The company is leveraging decades of accumulated knowledge about how activation of estrogen receptors in a specific manner affects gene regulation. Researchers at ENDECE Neural have identified small-molecule compounds that upregulate key genes in pathways involved in promoting myelin synthesis. ENDECE Neural is developing NDC-1308, which appears to directly induce OPCs to differentiate into mature oligodendrocytes that restore the depleted myelin sheath in patients with MS. ENDECE Neural discovered and owns the intellectual property surrounding its compounds, and the company’s management team has an extensive track record of successfully taking products from the laboratory through FDA approval and commercial release.


News Articles [310 Associated News Articles listed on BioPortfolio]

Researchers propose a novel tripartite mechanism of neural memory

The overwhelming quest in cognitive science has been (and still is) to scientifically describe mental processes on a molecular level, notably memory and intelligence, and attempt to mimic them technol...

Neural Implants Inspired by Mosquitos

NewsResearchers have engineered a better way to insert more flexible neural implants into soft brain tissue.Contributed Author: 

Optical neural network demo

Researchers have made a silicon chip that distributes optical signals precisely across a miniature brain-like grid, showcasing a potential new design for neural networks.

This New Chip Design Could Make Neural Nets More Efficient and a Lot Faster

Neural networks running on GPUs have achieved some amazing advances in artificial intelligence, but the two are accidental bedfellows. IBM researchers hope a new chip design tailored specifically to r...

Neural Cells Repair Spinal Cord Damage without Triggering Rejection

Stem cell researchers working with a porcine model have demonstrated the potential for using neural precursor cells (NPCs) – derived...

Formate prevents most folic acid-resistant neural tube defects in mice

(Baylor College of Medicine) A multi-institutional research team has developed a novel folic acid-resistant neural tube defect mouse model of the human condition by silencing the Slc25a32 gene, and, i...

When we sign, we build phrases with similar neural mechanisms as when we speak

Differences between signed and spoken languages are significant, yet the underlying neural processes we use to create complex expressions are quite similar for both, a team of researchers has found.

Glycosphingolipid metabolic reprogramming drives neural differentiation

Neural development is accomplished by differentiation events leading to metabolic reprogramming. Glycosphingolipid metabolism is reprogrammed during neural development with a switch from globo- to gan...

PubMed Articles [1084 Associated PubMed Articles listed on BioPortfolio]

Code Under Construction: Neural Coding Over Development.

Developing animals must begin to interact with the world before their neural development is complete. This means they must build neural codes appropriate for turning sensory inputs into motor outputs ...

The Neural Border: Induction, Specification and Maturation of the territory that generates Neural Crest cells.

The neural crest is induced at the edge between the neural plate and the nonneural ectoderm, in an area called the neural (plate) border, during gastrulation and neurulation. In recent years, many stu...

Corrigendum to "Hopfield networks as a model of prototype-based category learning: A method to distinguish trained, spurious, and prototypical attractors" Neural Netw. 91 (2017) 76-84.

Cre-driver lines used for genetic fate mapping of neural crest cells in the mouse: An overview.

The neural crest is one of the embryonic structures with the broadest developmental potential in vertebrates. Morphologically, neural crest cells emerge during neurulation in the dorsal folds of the n...

Neural stem cell heterogeneity in the mammalian forebrain.

The brain was long considered an organ that underwent very little change after development. It is now well established that the mammalian central nervous system contains neural stem cells that generat...

Clinical Trials [666 Associated Clinical Trials listed on BioPortfolio]

Neural Enabled Prosthesis for Upper Limb Amputees

This study is designed to evaluate the feasibility of The Adaptive Neural Systems Neural-Enabled Prosthetic Hand (ANS-NEPH) system.

Cannabinoids, Neural Synchrony, and Information Processing

The study examines the effects of delta-9-tetrahydrocannabinol (Δ9-THC), the principal active ingredient of cannabis, on neural synchrony. Neural synchrony is studied using electroencepha...

Impulsivity, Neural Deficits and Cocaine Addiction

The purpose of this study is to assess neurocognitive and associated neural regions/circuitry disruptions relevant to impulsive relapse in cocaine-addicted subjects, and the relationship o...

Effects of Nervous System Mobilization

This study aims to compare the effect of tension neural mobilization versus sliding neural mobilization of the peroneal nerve on the heat and cold threshold, on pressure pain threshold and...

Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS)

Primary aim of the trial 1. to verify safety and tolerability of expanded human fetal neural stem cells 2. to verify safety and tolerability of a microsurgery human fetal neural stem...

Companies [40 Associated Companies listed on BioPortfolio]

ENDECE Neural

ENDECE Neural is a private biotechnology company at the forefront of developing therapies to repair and potentially reverse damage caused by devastating neurological diseases such...

ENDECE

ENDECE’s core business relies on the in-house rational design of new chemical entities that control molecular “switches” which impact cancer cell growth. The compan...

Neural Analytics, Inc.

Neural Analytics was founded in 2013 to create products and services to measure, diagnose and track brain health. The company’s current focus is on acute ischemic stroke, TBI...

Renovo Neural Inc.

Renovo Neural Inc. (http://www.renovoneural.com/) is a privately held company in Cleveland, OH. The company is a specialized research organization providing services to biotech, ...

Neural Analytics Inc.

Neural Analytics is creating products and services to measure, diagnose and track brain health with a current focus on Traumatic Brain Injury (TBI). NA combines leading edge da...

More Information about "ENDECE Neural" on BioPortfolio

We have published hundreds of ENDECE Neural news stories on BioPortfolio along with dozens of ENDECE Neural Clinical Trials and PubMed Articles about ENDECE Neural for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of ENDECE Neural Companies in our database. You can also find out about relevant ENDECE Neural Drugs and Medications on this site too.

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Relevant Topics

Biotechnology - Biotech
"using living things to create products or to do tasks for humans" About Biotechnology - Biotech Biotechnology is the practice of using plants, animals and micro-organisms such as bacteria, as well as biological processes - such as the ripen...

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The spinal cord is a bundle of nerves that runs down the middle of the back which carry signals back and forth between the body and brain. It is protected by vertebrae, which are the bone disks that make up the spine. An accident that damages the verte...

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Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...


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