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ENDECE Neural Company Profile

22:24 EDT 17th June 2018 | BioPortfolio

ENDECE Neural is a private biotechnology company at the forefront of developing therapies to repair and potentially reverse damage caused by devastating neurological diseases such as multiple sclerosis (MS). A wholly owned subsidiary of ENDECE LLC, ENDECE Neural was founded in 2011 to focus on the development of what could be the first drug capable of inducing remyelination of damaged nerves in patients with MS. The company is leveraging decades of accumulated knowledge about how activation of estrogen receptors in a specific manner affects gene regulation. Researchers at ENDECE Neural have identified small-molecule compounds that upregulate key genes in pathways involved in promoting myelin synthesis. ENDECE Neural is developing NDC-1308, which appears to directly induce OPCs to differentiate into mature oligodendrocytes that restore the depleted myelin sheath in patients with MS. ENDECE Neural discovered and owns the intellectual property surrounding its compounds, and the company’s management team has an extensive track record of successfully taking products from the laboratory through FDA approval and commercial release.


News Articles [273 Associated News Articles listed on BioPortfolio]

Researchers propose a novel tripartite mechanism of neural memory

The overwhelming quest in cognitive science has been (and still is) to scientifically describe mental processes on a molecular level, notably memory and intelligence, and attempt to mimic them technol...

Neural networks everywhere

New chip reduces neural networks’ power consumption by up to 95 percent, making them practical for battery-powered devices. Most recent advances in artificial-intelligence systems such as speech- or...

Infographic: Searching for the Neural Basis of Gender

Brain studies have yielded a mixed picture of the neural similarities and differences between people of different genders.

Putting AI in Your Pocket: MIT Chip Cuts Neural Network Power Consumption by 95%

Neural networks are powerful things, but they need a lot of juice. Engineers at MIT have now developed a new chip that cuts neural nets’ power consumption by up to 95 percent, potentially allowing t...

Neural Implants Inspired by Mosquitos

NewsResearchers have engineered a better way to insert more flexible neural implants into soft brain tissue.Contributed Author: 

This New Chip Design Could Make Neural Nets More Efficient and a Lot Faster

Neural networks running on GPUs have achieved some amazing advances in artificial intelligence, but the two are accidental bedfellows. IBM researchers hope a new chip design tailored specifically to r...

Neural Cells Repair Spinal Cord Damage without Triggering Rejection

Stem cell researchers working with a porcine model have demonstrated the potential for using neural precursor cells (NPCs) – derived...

Formate prevents most folic acid-resistant neural tube defects in mice

(Baylor College of Medicine) A multi-institutional research team has developed a novel folic acid-resistant neural tube defect mouse model of the human condition by silencing the Slc25a32 gene, and, i...

PubMed Articles [995 Associated PubMed Articles listed on BioPortfolio]

Region stability analysis and tracking control of memristive recurrent neural network.

Memristor is firstly postulated by Leon Chua and realized by Hewlett-Packard (HP) laboratory. Research results show that memristor can be used to simulate the synapses of neurons. This paper presents ...

The Neural Border: Induction, Specification and Maturation of the territory that generates Neural Crest cells.

The neural crest is induced at the edge between the neural plate and the nonneural ectoderm, in an area called the neural (plate) border, during gastrulation and neurulation. In recent years, many stu...

Bioprinting for Neural Tissue Engineering.

Bioprinting is a method by which a cell-encapsulating bioink is patterned to create complex tissue architectures. Given the potential impact of this technology on neural research, we review the curren...

Corrigendum to "Hopfield networks as a model of prototype-based category learning: A method to distinguish trained, spurious, and prototypical attractors" Neural Netw. 91 (2017) 76-84.

What Is Neural Plasticity?

"Neural plasticity" refers to the capacity of the nervous system to modify itself, functionally and structurally, in response to experience and injury. As the various chapters in this volume show, pla...

Clinical Trials [602 Associated Clinical Trials listed on BioPortfolio]

Neural Enabled Prosthesis for Upper Limb Amputees

This study is designed to evaluate the feasibility of The Adaptive Neural Systems Neural-Enabled Prosthetic Hand (ANS-NEPH) system.

Cannabinoids, Neural Synchrony, and Information Processing

The study examines the effects of delta-9-tetrahydrocannabinol (Δ9-THC), the principal active ingredient of cannabis, on neural synchrony. Neural synchrony is studied using electroencepha...

Impulsivity, Neural Deficits and Cocaine Addiction

The purpose of this study is to assess neurocognitive and associated neural regions/circuitry disruptions relevant to impulsive relapse in cocaine-addicted subjects, and the relationship o...

Effects of Nervous System Mobilization

This study aims to compare the effect of tension neural mobilization versus sliding neural mobilization of the peroneal nerve on the heat and cold threshold, on pressure pain threshold and...

Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS)

Primary aim of the trial 1. to verify safety and tolerability of expanded human fetal neural stem cells 2. to verify safety and tolerability of a microsurgery human fetal neural stem...

Companies [40 Associated Companies listed on BioPortfolio]

ENDECE Neural

ENDECE Neural is a private biotechnology company at the forefront of developing therapies to repair and potentially reverse damage caused by devastating neurological diseases such...

ENDECE

ENDECE’s core business relies on the in-house rational design of new chemical entities that control molecular “switches” which impact cancer cell growth. The compan...

Neural Analytics, Inc.

Neural Analytics was founded in 2013 to create products and services to measure, diagnose and track brain health. The company’s current focus is on acute ischemic stroke, TBI...

Renovo Neural Inc.

Renovo Neural Inc. (http://www.renovoneural.com/) is a privately held company in Cleveland, OH. The company is a specialized research organization providing services to biotech, ...

Neural Analytics Inc.

Neural Analytics is creating products and services to measure, diagnose and track brain health with a current focus on Traumatic Brain Injury (TBI). NA combines leading edge da...

More Information about "ENDECE Neural" on BioPortfolio

We have published hundreds of ENDECE Neural news stories on BioPortfolio along with dozens of ENDECE Neural Clinical Trials and PubMed Articles about ENDECE Neural for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of ENDECE Neural Companies in our database. You can also find out about relevant ENDECE Neural Drugs and Medications on this site too.

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Relevant Topics

Biotechnology - Biotech
"using living things to create products or to do tasks for humans" About Biotechnology - Biotech Biotechnology is the practice of using plants, animals and micro-organisms such as bacteria, as well as biological processes - such as the ripen...

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The spinal cord is a bundle of nerves that runs down the middle of the back which carry signals back and forth between the body and brain. It is protected by vertebrae, which are the bone disks that make up the spine. An accident that damages the verte...

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