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ENDECE Neural Company Profile

10:34 EST 13th December 2018 | BioPortfolio

ENDECE Neural is a private biotechnology company at the forefront of developing therapies to repair and potentially reverse damage caused by devastating neurological diseases such as multiple sclerosis (MS). A wholly owned subsidiary of ENDECE LLC, ENDECE Neural was founded in 2011 to focus on the development of what could be the first drug capable of inducing remyelination of damaged nerves in patients with MS. The company is leveraging decades of accumulated knowledge about how activation of estrogen receptors in a specific manner affects gene regulation. Researchers at ENDECE Neural have identified small-molecule compounds that upregulate key genes in pathways involved in promoting myelin synthesis. ENDECE Neural is developing NDC-1308, which appears to directly induce OPCs to differentiate into mature oligodendrocytes that restore the depleted myelin sheath in patients with MS. ENDECE Neural discovered and owns the intellectual property surrounding its compounds, and the company’s management team has an extensive track record of successfully taking products from the laboratory through FDA approval and commercial release.


News Articles [307 Associated News Articles listed on BioPortfolio]

Single Cell RNA-Seq Scrutinized by Neural Nets

Neural networks and supervised machine learning techniques can efficiently characterize cells that have been studied using single cell RNA-sequencing (scRNA-seq). The post Single Cell RNA-Seq Scrutin...

The protein Matrin-3 determines the fate of neural stem cells in brain development

(Kumamoto University) A Japanese research group has discovered a new neurogenic mechanism responsible for brain development. By applying proprietary technology for detecting trace proteins, they found...

Optical neural network demo

Researchers have made a silicon chip that distributes optical signals precisely across a miniature brain-like grid, showcasing a potential new design for neural networks.

This New Chip Design Could Make Neural Nets More Efficient and a Lot Faster

Neural networks running on GPUs have achieved some amazing advances in artificial intelligence, but the two are accidental bedfellows. IBM researchers hope a new chip design tailored specifically to r...

Neuroscientists study how neural function improves during adolescence

One of the outstanding questions in neurodevelopment research has been identifying how connections in the brain change to improve neural function during childhood and adolescence.

Breakthrough in construction of computers for mimicking human brain

(Frontiers) A computer built to mimic the brain's neural networks produces similar results to that of the best brain-simulation supercomputer software currently used for neural-signaling research. Tes...

Medical News Today: Unraveling the neural code of the anxious brain

By measuring the brain activity of participants across a series of days, scientists have encountered the neural signature of low mood in anxious brains.

Convolutional Neural Network Tops Clinicians for Melanoma ID

FRIDAY, June 1, 2018 -- The diagnostic performance of a deep learning convolutional neural network (CNN) seems better than that of dermatologists, according to a study published online May 28 in the A...

PubMed Articles [1117 Associated PubMed Articles listed on BioPortfolio]

Code Under Construction: Neural Coding Over Development.

Developing animals must begin to interact with the world before their neural development is complete. This means they must build neural codes appropriate for turning sensory inputs into motor outputs ...

The Neural Border: Induction, Specification and Maturation of the territory that generates Neural Crest cells.

The neural crest is induced at the edge between the neural plate and the nonneural ectoderm, in an area called the neural (plate) border, during gastrulation and neurulation. In recent years, many stu...

Corrigendum to "Hopfield networks as a model of prototype-based category learning: A method to distinguish trained, spurious, and prototypical attractors" Neural Netw. 91 (2017) 76-84.

Mechanisms of Neural Crest Migration.

Neural crest cells are a transient embryonic cell population that migrate collectively to various locations throughout the embryo to contribute a number of cell types to several organs. After inductio...

Neural stem cell heterogeneity in the mammalian forebrain.

The brain was long considered an organ that underwent very little change after development. It is now well established that the mammalian central nervous system contains neural stem cells that generat...

Clinical Trials [710 Associated Clinical Trials listed on BioPortfolio]

Neural Enabled Prosthesis for Upper Limb Amputees

This study is designed to evaluate the feasibility of The Adaptive Neural Systems Neural-Enabled Prosthetic Hand (ANS-NEPH) system.

Cannabinoids, Neural Synchrony, and Information Processing

The study examines the effects of delta-9-tetrahydrocannabinol (Δ9-THC), the principal active ingredient of cannabis, on neural synchrony. Neural synchrony is studied using electroencepha...

Impulsivity, Neural Deficits and Cocaine Addiction

The purpose of this study is to assess neurocognitive and associated neural regions/circuitry disruptions relevant to impulsive relapse in cocaine-addicted subjects, and the relationship o...

Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation

The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareuni...

Effects of Nervous System Mobilization

This study aims to compare the effect of tension neural mobilization versus sliding neural mobilization of the peroneal nerve on the heat and cold threshold, on pressure pain threshold and...

Companies [40 Associated Companies listed on BioPortfolio]

ENDECE Neural

ENDECE Neural is a private biotechnology company at the forefront of developing therapies to repair and potentially reverse damage caused by devastating neurological diseases such...

ENDECE

ENDECE’s core business relies on the in-house rational design of new chemical entities that control molecular “switches” which impact cancer cell growth. The compan...

Neural Analytics, Inc.

Neural Analytics was founded in 2013 to create products and services to measure, diagnose and track brain health. The company’s current focus is on acute ischemic stroke, TBI...

Renovo Neural Inc.

Renovo Neural Inc. (http://www.renovoneural.com/) is a privately held company in Cleveland, OH. The company is a specialized research organization providing services to biotech, ...

Neural Analytics Inc.

Neural Analytics is creating products and services to measure, diagnose and track brain health with a current focus on Traumatic Brain Injury (TBI). NA combines leading edge da...

More Information about "ENDECE Neural" on BioPortfolio

We have published hundreds of ENDECE Neural news stories on BioPortfolio along with dozens of ENDECE Neural Clinical Trials and PubMed Articles about ENDECE Neural for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of ENDECE Neural Companies in our database. You can also find out about relevant ENDECE Neural Drugs and Medications on this site too.

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