F-star Company Profile

23:27 EDT 20th March 2018 | BioPortfolio

F-star is a biopharmaceutical company developing novel bispecific antibody products to improve the treatment of cancer.

F-star is a leader in the development of novel bispecific antibodies

F-star is an oncology-focused biopharmaceutical company dedicated to developing novel bispecific antibody products that significantly improve the standard of care for patients.

Our Modular Antibody Technology™ allows us to rapidly discover and develop bispecific antibodies by introducing additional binding sites to the constant region of an antibody. It combines the power of our Fcab™ technology with traditional antibodies to identify the most appropriate target combinations, thus providing the opportunity to deliver products with the greatest therapeutic advantage to patients.

Developing genuine bispecific monoclonal antibodies

Our technology capitalizes on decades of experience with traditional antibody technology, while overcoming the limitations in the development and manufacture of bispecific antibodies.

Our experienced and proven team is well-positioned to leverage the strength of our proprietary bispecific antibody platform and to lead the advancement of Fcab-based antibodies to the clinic.

F-star funding secured through investors and strategic partnerships

To date F-star has raised more than €38 million in venture capital from VC investors: Aescap Venture, Atlas Venture, Novo Ventures, and TVM Capital; as well as from corporate investors: Merck Serono Ventures, MP Healthcare Venture Management, and SR One.

The company has two major alliances with Boehringer Ingelheim and Merck Serono, each covering multiple targets. The partnerships provide F-star with technology access fees, research funding, plus development and commercialization milestones, and royalties.

An asset-centric vehicle (“F-star Alpha Ltd.”) has been established to create greater commercial and financial flexibility for F-star, the investors, and future partners.


Schwarzenbergplatz 7


Phone: 44 7881 244 040

News Articles [376 Associated News Articles listed on BioPortfolio]

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Marine researchers say recent sea star wasting disease epidemic defies prediction

(University of California - Santa Cruz) Beginning in 2013, a mysterious disease crippled sea star populations up and down the U.S. west coast. Over a matter of months, many sea star species died in re...

Regal E-Walk Is Your Official Star Wars Command Center for Star Wars: The Last Jedi

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CMS Updates Hospital Star Rating Formula on Hospital Compare

The Centers for Medicare & Medicaid Services recently announced its updated Hospital Compare star rating system. The agency had postponed the release of the ratings for more than five months to ad...

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PubMed Articles [106 Associated PubMed Articles listed on BioPortfolio]

Free Surface Relaxations of Star-Shaped Polymer Films.

The surface relaxation dynamics of supported star-shaped polymer thin films are shown to be slower than the bulk, persisting up to temperatures at least 50 K above the bulk glass transition temperatu...

An Extended Kalman Filter-Based Attitude Tracking Algorithm for Star Sensors.

Efficiency and reliability are key issues when a star sensor operates in tracking mode. In the case of high attitude dynamics, the performance of existing attitude tracking algorithms degenerates rapi...

STAR syndrome plus: The first description of a female patient with the lethal form.

The STAR syndrome is a rare X-linked dominant developmental disorder caused by point mutations in the single FAM58A gene or deletions involving FAM58A and its flanking genes. The STAR phenotype is cha...

Black-hole-regulated star formation in massive galaxies.

Supermassive black holes, with masses more than a million times that of the Sun, seem to inhabit the centres of all massive galaxies. Cosmologically motivated theories of galaxy formation require feed...

Involvement of Adenosine Monophosphate Activated Kinase in Interleukin-6 Regulation of Steroidogenic Acute Regulatory Protein and Cholesterol Side Chain Cleavage Enzyme in the Bovine Zona Fasciculata and Zona Reticularis.

In bovine adrenal zona fasciculata (ZF) and NCI-H295R cells, interleukin-6 (IL-6) increases cortisol release, increases expression of steroidogenic acute regulatory protein (StAR), cholesterol side ch...

Clinical Trials [73 Associated Clinical Trials listed on BioPortfolio]

Outcomes From Home in Patients Recovering From Major Gynecologic Cancer Surgery: Measuring Symptoms and Health-related Quality of Life

This study is being done to see if most patients are willing and able to report how they are feeling after surgery using the internet, and if this information can help doctors and nurses d...

Cognitive Aging - STAR

Cognitive outcomes in Co-STAR participants will be compared with those from participants in a parallel study of the effects of HT on cognitive outcomes, WHISCA. A comparison of the Co-STAR...

Feasibility Study of the Head and Neck Survivorship Tool: Assessment and Recommendations (HN-STAR)

This study is being done to understand how survivors of head and neck cancer think they can make HN-STAR (the Survivor Self-Assessment, the survivorship clinic experience, and the Survivor...

ID Administration of fIPV Using Intradermal Adapters vs. BCG Syringe

The investigators will assess the usability and immune response following fractional dose inactivated polio virus vaccine (fIPV) administration with two novel intradermal adapters (ID adap...

Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™

Prospective, multicenter, bilaterally-treated, open-label, non-randomized clinical trial.

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F-star is a biopharmaceutical company dedicated to developing novel bispecific antibody products that provide a significant improvement over the current standard of care. Given it...

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