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Glactone Pharma AB Company Profile

12:04 EDT 25th June 2018 | BioPortfolio

Glactone Pharma AB is developing a drug for the treatment of castration resistant prostate cancer. Research has shown that the natural product galiellalactone can modulate a signaling protein (STAT3) that is over activated in cancer cells. The goal is to develop drugs against metastasizing cancer where galiellalactone is used as a chemical starting point to make new novel, patentable compounds. Glactone is situated in Helsingborg, Sweden.

Prostate cancer is the most common cancer in the western world and affects hundreds of thousands of men each year and 40 percent of all prostate cancerpatients will develop so-called castration resistant prostate cancer (CRPC). There is currently no effective treatment for this phase of the disease and the effect on prolonging the patient’s life is, unfortunately, very limited. Glactone Pharma is developing a new treatment paradigm with a drug for this particular phase of the disease to address a huge unmet medical need and help change patients lives.

Treating CRPC by targeting STAT3

  • Prostate cancer is the most common cancer in the western world
  • castration resistant prostate cancer (CRPC) affects approximately 40 percent of all prostate cancer patients
  • Great need for effective treatment for this phase of the disease
  • STAT3 (signal transducer and activator of transcription 3) is a transcription factor/signaling protein
  • STAT3 regulates cancer cell growth and survival, promote metastatic progression and is associated with drug resistance
  • STAT3 activation is associated with advanced stage of prostate cancer (CRPC) .
  • Inhibition of STAT3 may be a novel and highly promising treatment strategy for patients with advanced prostate cancer and CRPC.

Location

Kullagatan 8
Helsingborg
252 20
Sweden

Contact

Phone: +46 (0) 70-676 00 08
Email: an.tornell@pulsinvest.se


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